21 items (Odobenus rosmarus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IRS2	Insulin receptor substrate 2. (1327 aa)
	SNX1	Sorting nexin-1 isoform X1. (520 aa)
	SNX4	Sorting nexin-4 isoform X1. (450 aa)
	BRWD3	Bromodomain and WD repeat-containing protein 3 isoform X1. (1800 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	CCDC88A	Girdin isoform X1. (1873 aa)
	LOC101378833	Insulin receptor substrate 2-like. (528 aa)
	ELP6	Elongator complex protein 6. (266 aa)
	IRS4	LOW QUALITY PROTEIN: insulin receptor substrate 4. (1307 aa)
	PHIP	PH-interacting protein. (1821 aa)
	LMBRD1	Probable lysosomal cobalamin transporter. (544 aa)
	ENPP1	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (925 aa)
	SNX2	Sorting nexin-2 isoform X1. (523 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1304 aa)
	SHC1	SHC-transforming protein 1 isoform X1. (609 aa)
	SORBS1	Sorbin and SH3 domain-containing protein 1 isoform X1. (1291 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
	GRB10	Growth factor receptor-bound protein 10. (586 aa)
	BRWD1	Bromodomain and WD repeat-containing protein 1 isoform X1. (2276 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
	IRS1	Insulin receptor substrate 1. (1233 aa)

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRWD1	PHIP	A0A2U3WQD0	A0A2U3VWY9	Bromodomain and WD repeat-containing protein 1 isoform X1.	PH-interacting protein.	0.741
BRWD3	PHIP	A0A2U3WFG9	A0A2U3VWY9	Bromodomain and WD repeat-containing protein 3 isoform X1.	PH-interacting protein.	0.518
GRB10	IGF1R	A0A2U3WZI7	A0A2U3ZLZ8	Growth factor receptor-bound protein 10.	Tyrosine-protein kinase receptor.	0.984
GRB10	INS	A0A2U3WZI7	A0A2U3W6R9	Growth factor receptor-bound protein 10.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.746
GRB10	IRS1	A0A2U3WZI7	A0A2U3WLJ5	Growth factor receptor-bound protein 10.	Insulin receptor substrate 1.	0.490
GRB10	IRS2	A0A2U3WZI7	A0A2U3WL54	Growth factor receptor-bound protein 10.	Insulin receptor substrate 2.	0.490
GRB10	LOC101378833	A0A2U3WZI7	A0A2U3VUV5	Growth factor receptor-bound protein 10.	Insulin receptor substrate 2-like.	0.490
GRB10	PIK3R1	A0A2U3WZI7	A0A2U3X1Z3	Growth factor receptor-bound protein 10.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.951
GRB10	SHC1	A0A2U3WZI7	A0A2U3ZJC4	Growth factor receptor-bound protein 10.	SHC-transforming protein 1 isoform X1.	0.411
IGF1R	GRB10	A0A2U3ZLZ8	A0A2U3WZI7	Tyrosine-protein kinase receptor.	Growth factor receptor-bound protein 10.	0.984
IGF1R	INS	A0A2U3ZLZ8	A0A2U3W6R9	Tyrosine-protein kinase receptor.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.998
IGF1R	IRS1	A0A2U3ZLZ8	A0A2U3WLJ5	Tyrosine-protein kinase receptor.	Insulin receptor substrate 1.	0.980
IGF1R	IRS2	A0A2U3ZLZ8	A0A2U3WL54	Tyrosine-protein kinase receptor.	Insulin receptor substrate 2.	0.980
IGF1R	IRS4	A0A2U3ZLZ8	A0A2U3VWM9	Tyrosine-protein kinase receptor.	LOW QUALITY PROTEIN: insulin receptor substrate 4.	0.980
IGF1R	LOC101378833	A0A2U3ZLZ8	A0A2U3VUV5	Tyrosine-protein kinase receptor.	Insulin receptor substrate 2-like.	0.980
IGF1R	PIK3R1	A0A2U3ZLZ8	A0A2U3X1Z3	Tyrosine-protein kinase receptor.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.971
IGF1R	PTPN11	A0A2U3ZLZ8	A0A2U3WN02	Tyrosine-protein kinase receptor.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.632
IGF1R	SHC1	A0A2U3ZLZ8	A0A2U3ZJC4	Tyrosine-protein kinase receptor.	SHC-transforming protein 1 isoform X1.	0.975
INS	GRB10	A0A2U3W6R9	A0A2U3WZI7	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Growth factor receptor-bound protein 10.	0.746
INS	IGF1R	A0A2U3W6R9	A0A2U3ZLZ8	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.998