STRINGSTRING
SMU1 SMU1 SF3B3 SF3B3 SF3B1 SF3B1 SART1 SART1 BUD31 BUD31 PLRG1 PLRG1 SYF2 SYF2 PRPF40A PRPF40A CASC3 CASC3 SF3B6 SF3B6 CWC25 CWC25 CCDC94 CCDC94 AMH AMH LSM7 LSM7 SF3A2 SF3A2 LSM3 LSM3 ISY1 ISY1 PRPF4 PRPF4 LOC101375442 LOC101375442 SF3B5 SF3B5 NHP2L1 NHP2L1 PHF5A PHF5A ZMAT2 ZMAT2 IK IK SNRPB SNRPB RBM8A RBM8A LOC101373629 LOC101373629 SNRPG SNRPG CCDC12 CCDC12 SNW1 SNW1 SNRNP200 SNRNP200 SF3A1 SF3A1 PRPF40B PRPF40B SNRPD2 SNRPD2 BCAS2 BCAS2 CWC27 CWC27 LOC101375942 LOC101375942 SNIP1 SNIP1 PPIE PPIE RBM22 RBM22 DHX15 DHX15 CWC22 CWC22 EIF4A3 EIF4A3 LSM4 LSM4 RNF113A RNF113A SNRPA1 SNRPA1 SNRNP40 SNRNP40 CDC40 CDC40 DHX8 DHX8 LOC101378288 LOC101378288 LSM8 LSM8 AQR AQR DHX16 DHX16 PRPF18 PRPF18 PRPF19 PRPF19 PRPF6 PRPF6 SNRPD1 SNRPD1 MFAP1 MFAP1 XAB2 XAB2 TFIP11 TFIP11 LOC101376578 LOC101376578 LOC101372449 LOC101372449 PRPF39 PRPF39 SNRNP70 SNRNP70 LSM2 LSM2 BUD13 BUD13 SNRPN SNRPN SNRPB2 SNRPB2 CDC5L CDC5L TXNL4A TXNL4A LOC101376975 LOC101376975 LUC7L3 LUC7L3 GCFC2 GCFC2 CCDC130 CCDC130 PRPF38A PRPF38A SNRPD3 SNRPD3 SF3A3 SF3A3 LUC7L LUC7L SRRM2 SRRM2 PRPF8 PRPF8 PRPF3 PRPF3 U2AF2 U2AF2 WBP4 WBP4 EFTUD2 EFTUD2 SNRPC SNRPC PRPF31 PRPF31 HTATSF1 HTATSF1 CRNKL1 CRNKL1 SF3B2 SF3B2 LOC101386064 LOC101386064
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMU1WD40 repeat-containing protein SMU1. (513 aa)
SF3B3Splicing factor 3B subunit 3. (1217 aa)
SF3B1Splicing factor 3B subunit 1 isoform X1. (1304 aa)
SART1U4/U6.U5 tri-snRNP-associated protein 1 isoform X1. (806 aa)
BUD31Protein BUD31 homolog. (144 aa)
PLRG1Pleiotropic regulator 1 isoform X1. (515 aa)
SYF2pre-mRNA-splicing factor SYF2. (246 aa)
PRPF40Apre-mRNA-processing factor 40 homolog A isoform X1. (994 aa)
CASC3Protein CASC3. (703 aa)
SF3B6Splicing factor 3B subunit 6. (125 aa)
CWC25pre-mRNA-splicing factor CWC25 homolog. (425 aa)
CCDC94Coiled-coil domain-containing protein 94. (324 aa)
AMHMuellerian-inhibiting factor. (578 aa)
LSM7U6 snRNA-associated Sm-like protein LSm7. (103 aa)
SF3A2Splicing factor 3A subunit 2. (471 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
ISY1pre-mRNA-splicing factor ISY1 homolog. (285 aa)
PRPF4U4/U6 small nuclear ribonucleoprotein Prp4. (521 aa)
LOC101375442Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
NHP2L1Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (163 aa)
PHF5APHD finger-like domain-containing protein 5A. (110 aa)
ZMAT2Zinc finger matrin-type protein 2. (199 aa)
IKProtein Red. (563 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
LOC101373629Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (123 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
CCDC12Coiled-coil domain-containing protein 12. (166 aa)
SNW1SNW domain-containing protein 1 isoform X1. (536 aa)
SNRNP200U5 small nuclear ribonucleoprotein 200 kDa helicase. (2136 aa)
SF3A1Splicing factor 3A subunit 1. (793 aa)
PRPF40Bpre-mRNA-processing factor 40 homolog B isoform X1. (871 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
BCAS2pre-mRNA-splicing factor SPF27. (225 aa)
CWC27Peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform X1. (472 aa)
LOC101375942RING finger protein 113A-like. (344 aa)
SNIP1Smad nuclear-interacting protein 1. (397 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
RBM22pre-mRNA-splicing factor RBM22. (419 aa)
DHX15pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15. (795 aa)
CWC22pre-mRNA-splicing factor CWC22 homolog isoform X1. (908 aa)
EIF4A3Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (411 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa)
RNF113ARING finger protein 113A. (344 aa)
SNRPA1U2 small nuclear ribonucleoprotein A. (255 aa)
SNRNP40U5 small nuclear ribonucleoprotein 40 kDa protein. (358 aa)
CDC40pre-mRNA-processing factor 17. (579 aa)
DHX8ATP-dependent RNA helicase DHX8. (1220 aa)
LOC101378288Dentin sialophosphoprotein-like. (1380 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1491 aa)
DHX16Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16. (1043 aa)
PRPF18pre-mRNA-splicing factor 18. (342 aa)
PRPF19pre-mRNA-processing factor 19. (504 aa)
PRPF6pre-mRNA-processing factor 6 isoform X1. (941 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
MFAP1Microfibrillar-associated protein 1. (439 aa)
XAB2pre-mRNA-splicing factor SYF1. (855 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa)
LOC101376578Small nuclear ribonucleoprotein F-like. (86 aa)
LOC101372449Putative RNA-binding protein Luc7-like 2 isoform X1. (392 aa)
PRPF39pre-mRNA-processing factor 39 isoform X1. (667 aa)
SNRNP70U1 small nuclear ribonucleoprotein 70 kDa isoform X1. (438 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
BUD13BUD13 homolog. (490 aa)
SNRPNSmall nuclear ribonucleoprotein-associated protein. (240 aa)
SNRPB2U2 small nuclear ribonucleoprotein B'' isoform X1. (225 aa)
CDC5LCell division cycle 5-like protein isoform X1. (802 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
LOC101376975pre-mRNA-splicing factor SYF2-like. (265 aa)
LUC7L3Luc7-like protein 3 isoform X1. (489 aa)
GCFC2GC-rich sequence DNA-binding factor 2 isoform X1. (783 aa)
CCDC130Coiled-coil domain-containing protein 130 isoform X1. (476 aa)
PRPF38Apre-mRNA-splicing factor 38A isoform X1. (319 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
SF3A3Splicing factor 3A subunit 3 isoform X1. (583 aa)
LUC7LPutative RNA-binding protein Luc7-like 1 isoform X1. (377 aa)
SRRM2Serine/arginine repetitive matrix protein 2. (195 aa)
PRPF8pre-mRNA-processing-splicing factor 8. (2335 aa)
PRPF3U4/U6 small nuclear ribonucleoprotein Prp3 isoform X1. (683 aa)
U2AF2U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (475 aa)
WBP4WW domain-binding protein 4 isoform X1. (392 aa)
EFTUD2116 kDa U5 small nuclear ribonucleoprotein component isoform X1. (972 aa)
SNRPCU1 small nuclear ribonucleoprotein C isoform X1. (171 aa)
PRPF31U4/U6 small nuclear ribonucleoprotein Prp31 isoform X1. (499 aa)
HTATSF1HIV Tat-specific factor 1 isoform X1. (767 aa)
CRNKL1LOW QUALITY PROTEIN: crooked neck-like protein 1. (829 aa)
SF3B2Splicing factor 3B subunit 2 isoform X1. (896 aa)
LOC101386064LOW QUALITY PROTEIN: pre-mRNA-processing factor 40 homolog A-like. (914 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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