STRINGSTRING
ATF4 ATF4 PGM5 PGM5 H6PD H6PD KAT2B KAT2B PIK3CA PIK3CA GDPGP1 GDPGP1 TP53 TP53 HK2 HK2 MDH2 MDH2 ALDOC ALDOC AKT3 AKT3 GPD1 GPD1 HK3 HK3 PDHA1 PDHA1 SLC39A14 SLC39A14 LOC101366299 LOC101366299 TFAP2E TFAP2E PPARGC1A PPARGC1A LOC101380793 LOC101380793 IGF2 IGF2 INS INS KCNQ1 KCNQ1 LOC101373832 LOC101373832 LOC101365418 LOC101365418 FAM132A FAM132A FBP2 FBP2 FBP1 FBP1 PRKAA1 PRKAA1 PFKP PFKP GALM GALM SDS SDS G6PC G6PC PFKL PFKL PGK1 PGK1 WDR5 WDR5 PDHB PDHB KCNJ11 KCNJ11 CRY1 CRY1 SLC37A4 SLC37A4 PGM1 PGM1 ADIPOQ ADIPOQ GPI GPI TPI1 TPI1 GAPDH GAPDH PGK2 PGK2 KBTBD2 KBTBD2 ATF3 ATF3 PDX1 PDX1 TNF TNF TIGAR TIGAR TFAP2B TFAP2B GAPDHS GAPDHS LOC101379418 LOC101379418 WDTC1 WDTC1 PGM2 PGM2 LOC101372056 LOC101372056 LOC101382994 LOC101382994 PCK2 PCK2 FOXK2 FOXK2 LOC101385013 LOC101385013 CDV3 CDV3 LEPR LEPR KAT2A KAT2A LOC101376545 LOC101376545 G6PC3 G6PC3 HK1 HK1 GCK GCK G6PD G6PD NPY1R NPY1R OMA1 OMA1 ADPGK ADPGK LOC101366853 LOC101366853 LRP5 LRP5 PCK1 PCK1 LOC101366862 LOC101366862 PDHA2 PDHA2 PGM2L1 PGM2L1 APOD APOD LOC101376965 LOC101376965 HKDC1 HKDC1 FABP5 FABP5 PC PC BRAT1 BRAT1 FOXK1 FOXK1 BAD BAD SERPINA12 SERPINA12 AKT1 AKT1 PFKM PFKM AKT2 AKT2 FBN1 FBN1 G6PC2 G6PC2 LOC101363102 LOC101363102
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
PGM5Phosphoglucomutase-like protein 5; Belongs to the phosphohexose mutase family. (567 aa)
H6PDGDH/6PGL endoplasmic bifunctional protein. (804 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
GDPGP1GDP-D-glucose phosphorylase 1. (385 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
HK2Hexokinase-2. (917 aa)
MDH2Malate dehydrogenase. (338 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (349 aa)
HK3Hexokinase-3. (924 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
SLC39A14Zinc transporter ZIP14 isoform X2. (490 aa)
LOC101366299Glyceraldehyde-3-phosphate dehydrogenase-like; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)
TFAP2ETranscription factor AP-2-epsilon. (440 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (803 aa)
LOC101380793Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
IGF2LOW QUALITY PROTEIN: insulin-like growth factor II. (198 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (671 aa)
LOC101373832L-xylulose reductase. (244 aa)
LOC101365418LOW QUALITY PROTEIN: carbonyl reductase [NADPH] 2-like. (244 aa)
FAM132AAdipolin. (307 aa)
FBP2Fructose-1,6-bisphosphatase isozyme 2; Belongs to the FBPase class 1 family. (335 aa)
FBP1Fructose-1,6-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
PRKAA1Non-specific serine/threonine protein kinase. (528 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (790 aa)
GALMAldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (342 aa)
SDSL-serine dehydratase/L-threonine deaminase. (328 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
PGK1Phosphoglycerate kinase. (417 aa)
WDR5WD repeat-containing protein 5. (334 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
KCNJ11ATP-sensitive inward rectifier potassium channel 11. (390 aa)
CRY1Cryptochrome-1. (534 aa)
SLC37A4Glucose-6-phosphate translocase isoform X1. (451 aa)
PGM1Phosphoglucomutase-1 isoform X1; Belongs to the phosphohexose mutase family. (580 aa)
ADIPOQAdiponectin isoform X1. (266 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (557 aa)
TPI1Triosephosphate isomerase. (286 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
PGK2Phosphoglycerate kinase. (417 aa)
KBTBD2Kelch repeat and BTB domain-containing protein 2. (623 aa)
ATF3Cyclic AMP-dependent transcription factor ATF-3. (181 aa)
PDX1Pancreas/duodenum homeobox protein 1. (283 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
TIGARFructose-2,6-bisphosphatase TIGAR. (270 aa)
TFAP2BTranscription factor AP-2-beta isoform X1. (469 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (409 aa)
LOC101379418Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (155 aa)
WDTC1WD and tetratricopeptide repeats protein 1 isoform X1. (681 aa)
PGM2Phosphoglucomutase-2. (615 aa)
LOC101372056Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
LOC101382994Glyceraldehyde-3-phosphate dehydrogenase-like; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)
PCK2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1. (668 aa)
FOXK2Forkhead box protein K2. (555 aa)
LOC101385013Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
CDV3Protein CDV3 homolog isoform X1. (107 aa)
LEPRLeptin receptor isoform X1. (1166 aa)
KAT2AHistone acetyltransferase KAT2A isoform X1. (838 aa)
LOC101376545Malate dehydrogenase. (320 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
HK1Hexokinase-1 isoform X1. (935 aa)
GCKPhosphotransferase. (458 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (555 aa)
NPY1RNeuropeptide Y receptor type 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
OMA1Metalloendopeptidase OMA1, mitochondrial. (525 aa)
ADPGKADP-dependent glucokinase isoform X1. (497 aa)
LOC101366853Glyceraldehyde-3-phosphate dehydrogenase-like; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (327 aa)
LRP5Low-density lipoprotein receptor-related protein 5. (1451 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP] isoform X1. (622 aa)
LOC101366862Malate dehydrogenase. (338 aa)
PDHA2Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (391 aa)
PGM2L1Glucose 1,6-bisphosphate synthase. (622 aa)
APODApolipoprotein D. (212 aa)
LOC101376965Malate dehydrogenase. (338 aa)
HKDC1Putative hexokinase HKDC1. (917 aa)
FABP5Fatty acid-binding protein, epidermal; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1178 aa)
BRAT1BRCA1-associated ATM activator 1. (822 aa)
FOXK1Forkhead box protein K1. (611 aa)
BADBcl2-associated agonist of cell death. (168 aa)
SERPINA12Serpin A12; Belongs to the serpin family. (416 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (859 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
FBN1Fibrillin-1. (2868 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (356 aa)
LOC101363102Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
Server load: low (18%) [HD]