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| | WDR48 | WD repeat-containing protein 48 isoform X1. (677 aa) |
| | NSMCE1 | Non-structural maintenance of chromosomes element 1 homolog isoform X1. (283 aa) |
| | SLX1A | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (274 aa) |
| | PAGR1 | PAXIP1-associated glutamate-rich protein 1. (254 aa) |
| | INO80E | INO80 complex subunit E isoform X1. (244 aa) |
| | SMC5 | Structural maintenance of chromosomes protein 5. (1107 aa) |
| | RAD51B | DNA repair protein RAD51 homolog 2 isoform X2. (350 aa) |
| | ZFYVE26 | Zinc finger FYVE domain-containing protein 26. (2542 aa) |
| | BRIP1 | Fanconi anemia group J protein. (1216 aa) |
| | KIAA1841 | Uncharacterized protein KIAA1841 homolog. (718 aa) |
| | RAD51C | DNA repair protein RAD51 homolog 3 isoform X1. (371 aa) |
| | MCM9 | DNA helicase MCM9; Belongs to the MCM family. (1142 aa) |
| | AP5S1 | AP-5 complex subunit sigma-1. (200 aa) |
| | MCM8 | DNA helicase MCM8 isoform X1; Belongs to the MCM family. (833 aa) |
| | BLM | Bloom syndrome protein isoform X1. (1428 aa) |
| | RPAIN | LOW QUALITY PROTEIN: RPA-interacting protein. (281 aa) |
| | PALB2 | Partner and localizer of BRCA2. (1178 aa) |
| | SWSAP1 | ATPase SWSAP1. (253 aa) |
| | CCDC36 | Coiled-coil domain-containing protein 36. (592 aa) |
| | BATF | Basic leucine zipper transcriptional factor ATF-like. (125 aa) |
| | ATAD5 | ATPase family AAA domain-containing protein 5. (1847 aa) |
| | INO80 | DNA helicase INO80. (1562 aa) |
| | RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa) |
| | RAD54L | DNA repair and recombination protein RAD54-like. (747 aa) |
| | TONSL | Tonsoku-like protein. (1372 aa) |
| | RECQL4 | ATP-dependent DNA helicase Q4. (1183 aa) |
| | LIG1 | DNA ligase. (915 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa) |
| | RMI2 | recQ-mediated genome instability protein 2. (161 aa) |
| | SYCP1 | Synaptonemal complex protein 1. (977 aa) |
| | XRCC5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa) |
| | CCR6 | C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | NABP2 | SOSS complex subunit B1. (211 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) |
| | STAT6 | Signal transducer and activator of transcription. (844 aa) |
| | EPC1 | Enhancer of polycomb homolog. (844 aa) |
| | POLL | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (575 aa) |
| | MCMDC2 | MCM domain-containing protein 2. (681 aa) |
| | MND1 | Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (205 aa) |
| | CDC7 | Cell division cycle 7-related protein kinase isoform X1. (575 aa) |
| | SFPQ | Splicing factor, proline- and glutamine-rich. (700 aa) |
| | NHEJ1 | Non-homologous end-joining factor 1. (296 aa) |
| | INTS3 | Integrator complex subunit 3. (1041 aa) |
| | MEIOB | Meiosis-specific with OB domain-containing protein isoform X2. (471 aa) |
| | EME2 | Probable crossover junction endonuclease EME2. (381 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1364 aa) |
| | PAXIP1 | PAX-interacting protein 1. (1034 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | NIPBL | Nipped-B protein. (2803 aa) |
| | NSMCE4A | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (385 aa) |
| | STRA13 | Centromere protein X. (79 aa) |
| | ANKLE1 | LOW QUALITY PROTEIN: ankyrin repeat and LEM domain-containing protein 1. (672 aa) |
| | PGBD5 | piggyBac transposable element-derived protein 5. (409 aa) |
| | TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (983 aa) |
| | MSH3 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1126 aa) |
| | XRCC4 | DNA repair protein XRCC4. (333 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | HSF2BP | Heat shock factor 2-binding protein. (972 aa) |
| | HMGB1 | High mobility group protein B1. (207 aa) |
| | BRCA2 | Breast cancer type 2 susceptibility protein. (3150 aa) |
| | REV3L | DNA polymerase zeta catalytic subunit. (3128 aa) |
| | MMS22L | Protein MMS22-like. (1241 aa) |
| | LOC101383118 | Uncharacterized protein C17orf53 homolog. (724 aa) |
| | SMC6 | Structural maintenance of chromosomes protein 6. (1097 aa) |
| | GEN1 | Flap endonuclease GEN homolog 1. (907 aa) |
| | RAD51AP2 | RAD51-associated protein 2. (1154 aa) |
| | RMI1 | recQ-mediated genome instability protein 1. (638 aa) |
| | REC114 | Meiotic recombination protein REC114. (213 aa) |
| | UBR2 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1755 aa) |
| | XRCC1 | DNA repair protein XRCC1. (630 aa) |
| | RAD50 | DNA repair protein RAD50 isoform X1. (1312 aa) |
| | WRN | Werner syndrome ATP-dependent helicase. (1405 aa) |
| | XRCC2 | DNA repair protein XRCC2. (280 aa) |
| | ERCC4 | DNA repair endonuclease XPF. (916 aa) |
| | RAG2 | V(D)J recombination-activating protein 2. (527 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |
| | TFPT | TCF3 fusion partner isoform X1. (253 aa) |
| | HDAC10 | Histone deacetylase 10. (670 aa) |
| | FAN1 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1023 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (487 aa) |
| | CCDC155 | Protein KASH5. (565 aa) |
| | SHFM1 | 26S proteasome complex subunit DSS1. (70 aa) |
| | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14. (310 aa) |
| | NSMCE2 | E3 SUMO-protein ligase NSE2. (247 aa) |
| | LOC101380618 | mutS protein homolog 4. (501 aa) |
| | CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (260 aa) |
| | CNTD1 | Cyclin N-terminal domain-containing protein 1. (329 aa) |
| | PSMC3IP | Homologous-pairing protein 2 homolog isoform X1. (217 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (808 aa) |
| | DMC1 | Meiotic recombination protein DMC1/LIM15 homolog isoform X1; Belongs to the RecA family. (340 aa) |
| | LOC101386320 | Centromere protein S. (165 aa) |
| | UCHL5 | Ubiquitin carboxyl-terminal hydrolase. (329 aa) |
| | ACTR8 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa) |
| | TRIP13 | Pachytene checkpoint protein 2 homolog; Belongs to the AAA ATPase family. (432 aa) |
| | FBXO18 | F-box only protein 18. (972 aa) |
| | RAD52 | DNA repair protein RAD52 homolog. (431 aa) |
| | LOC101369098 | Uncharacterized protein C9orf84 homolog. (1446 aa) |
| | FOXP3 | Forkhead box protein P3 isoform X1. (455 aa) |
| | POLN | DNA polymerase nu. (871 aa) |
| | PRKDC | DNA-dependent protein kinase catalytic subunit isoform X1; Belongs to the PI3/PI4-kinase family. (4136 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (903 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | XRCC3 | DNA repair protein XRCC3. (338 aa) |
| | BCL11B | B-cell lymphoma/leukemia 11B isoform X1. (897 aa) |
| | RPA3 | Replication protein A 14 kDa subunit. (121 aa) |
| | TCF3 | Transcription factor E2-alpha isoform X1. (654 aa) |
| | MBTD1 | MBT domain-containing protein 1. (628 aa) |
| | EME1 | Crossover junction endonuclease EME1 isoform X2. (580 aa) |
| | TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1534 aa) |
| | AUNIP | Aurora kinase A and ninein-interacting protein. (357 aa) |
| | SWAP70 | Switch-associated protein 70 isoform X1. (585 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | RECQL5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (985 aa) |
| | AP5Z1 | AP-5 complex subunit zeta-1. (808 aa) |
| | MUS81 | Crossover junction endonuclease MUS81. (552 aa) |
| | SUPV3L1 | ATP-dependent RNA helicase SUPV3L1, mitochondrial. (789 aa) |
| | EXOSC6 | Exosome complex component MTR3. (272 aa) |
| | SAMHD1 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1. (627 aa) |
| | FANCD2 | Fanconi anemia group D2 protein. (1446 aa) |
| | NABP1 | SOSS complex subunit B2. (204 aa) |
| | GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (570 aa) |
| | TM4SF19 | Transmembrane 4 L6 family member 19 isoform X1. (209 aa) |
| | HELQ | LOW QUALITY PROTEIN: helicase POLQ-like. (1094 aa) |
| | TOP2B | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1614 aa) |
| | LOC105758394 | LOW QUALITY PROTEIN: uncharacterized protein LOC105758394. (351 aa) |
| | LOC101364550 | LOW QUALITY PROTEIN: uncharacterized protein C11orf80 homolog. (661 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (728 aa) |
| | FANCM | Fanconi anemia group M protein. (2051 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (555 aa) |
| | MRE11A | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (708 aa) |
| | LEF1 | Lymphoid enhancer-binding factor 1 isoform X1. (413 aa) |
| | LOC105758093 | LOW QUALITY PROTEIN: uncharacterized protein LOC105758093. (490 aa) |
| | VPRBP | Protein VPRBP isoform X1. (1510 aa) |
| | RTEL1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1305 aa) |
| | MSH4 | LOW QUALITY PROTEIN: mutS protein homolog 4; Belongs to the eukaryotic ribosomal protein eL42 family. (550 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein isoform X1. (1881 aa) |
| | PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (641 aa) |
| | RECQL | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (646 aa) |
| | TCF7 | Transcription factor 7 isoform X1. (419 aa) |
| | LOC101381859 | X-ray repair cross-complementing protein 6-like isoform X1. (607 aa) |
| | NUCKS1 | Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 isoform X1. (248 aa) |
| | SWI5 | LOW QUALITY PROTEIN: DNA repair protein SWI5 homolog. (127 aa) |
| | SLX4 | Structure-specific endonuclease subunit SLX4. (1757 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) |
| | LOC101368346 | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (311 aa) |
| | LOC101373553 | LOW QUALITY PROTEIN: double-strand-break repair protein rad21 homolog. (625 aa) |
| | SFR1 | Swi5-dependent recombination DNA repair protein 1 homolog isoform X1. (250 aa) |
| | LOC101378352 | Uncharacterized protein C1orf146 homolog. (181 aa) |
| | HFM1 | Probable ATP-dependent DNA helicase HFM1 isoform X1. (1480 aa) |
| | RNF212B | RING finger protein 212B. (300 aa) |
| | REC8 | Meiotic recombination protein REC8 homolog. (593 aa) |
| | ERCC1 | DNA excision repair protein ERCC-1 isoform X1. (350 aa) |
| | EXOSC3 | Exosome complex component RRP40. (164 aa) |
| | MEI4 | Meiosis-specific protein MEI4-like. (386 aa) |
| | LOC101370016 | Uncharacterized protein C19orf57 homolog. (707 aa) |
| | TPRKB | EKC/KEOPS complex subunit TPRKB isoform X1; Belongs to the CGI121/TPRKB family. (175 aa) |
| | LOC101386769 | E3 ubiquitin-protein ligase RNF138. (209 aa) |
| | TEX11 | Testis-expressed sequence 11 protein. (954 aa) |
| | PPP4C | Serine/threonine-protein phosphatase. (307 aa) |
| | INIP | SOSS complex subunit C. (116 aa) |
| | SPIDR | DNA repair-scaffolding protein. (794 aa) |
| | RNF212 | Probable E3 SUMO-protein ligase RNF212. (286 aa) |
| | LOC105757205 | LOW QUALITY PROTEIN: uncharacterized protein LOC105757205. (486 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | HMGB2 | High mobility group protein B2. (210 aa) |
| | XRCC6 | LOW QUALITY PROTEIN: X-ray repair cross-complementing protein 6. (607 aa) |
| | LOC101378834 | Double-strand-break repair protein rad21 homolog. (152 aa) |
| | FANCB | Fanconi anemia group B protein. (864 aa) |
| | RAD51D | DNA repair protein RAD51 homolog 4 isoform X1. (328 aa) |
| | LIG3 | DNA ligase. (999 aa) |
| | SPO11 | Meiotic recombination protein SPO11 isoform X1. (396 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | UNG | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (313 aa) |
| | ANKRD31 | LOW QUALITY PROTEIN: putative ankyrin repeat domain-containing protein 31. (1873 aa) |
| | RAD51AP1 | RAD51-associated protein 1 isoform X1. (354 aa) |
| | LOC101367731 | Breast cancer type 2 susceptibility protein homolog. (342 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa) |
| | LOC101368602 | Protein SIX6OS1. (588 aa) |
| | EXO1 | Exonuclease 1. (841 aa) |
| | MSH5 | mutS protein homolog 5 isoform X1. (833 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | CDC45 | Cell division control protein 45 homolog isoform X1. (570 aa) |
| | APEX2 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (515 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | EID3 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (370 aa) |
| | RBBP8 | DNA endonuclease RBBP8 isoform X1. (897 aa) |
| | RAD54B | DNA repair and recombination protein RAD54B isoform X1. (819 aa) |
| | BCL6 | B-cell lymphoma 6 protein. (706 aa) |
| | RAD21 | Double-strand-break repair protein rad21 homolog. (402 aa) |
| | LOC101384378 | Checkpoint protein; Belongs to the HUS1 family. (245 aa) |
| | CCNB1IP1 | E3 ubiquitin-protein ligase CCNB1IP1. (277 aa) |
| | RFWD3 | E3 ubiquitin-protein ligase RFWD3. (774 aa) |
| | APEX1 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (317 aa) |
| | TEP1 | Telomerase protein component 1. (2629 aa) |
| | DCLRE1C | LOW QUALITY PROTEIN: protein artemis. (692 aa) |
| | RHNO1 | RAD9, HUS1, RAD1-interacting nuclear orphan protein 1. (255 aa) |
