47 items (Odobenus rosmarus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101378833	Insulin receptor substrate 2-like. (528 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1304 aa)
	SHC1	SHC-transforming protein 1 isoform X1. (609 aa)
	SH2B2	LOW QUALITY PROTEIN: SH2B adapter protein 2. (813 aa)
	PDK2	Protein-serine/threonine kinase. (423 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
	STXBP4	Syntaxin-binding protein 4. (558 aa)
	CSRP3	Cysteine and glycine-rich protein 3 isoform X1. (194 aa)
	GRB10	Growth factor receptor-bound protein 10. (586 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (427 aa)
	INSR	Tyrosine-protein kinase receptor. (1381 aa)
	IRS1	Insulin receptor substrate 1. (1233 aa)
	IRS2	Insulin receptor substrate 2. (1327 aa)
	RARRES2	Retinoic acid receptor responder protein 2 isoform X1. (163 aa)
	CAV2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (416 aa)
	GSK3A	Glycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (483 aa)
	APPL1	DCC-interacting protein 13-alpha. (708 aa)
	GPLD1	Phosphatidylinositol-glycan-specific phospholipase D. (843 aa)
	NCOA5	Nuclear receptor coactivator 5 isoform X1. (579 aa)
	PIK3R2	Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	GSK3B	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
	RHOQ	Rho-related GTP-binding protein RhoQ. (205 aa)
	INSRR	Tyrosine-protein kinase receptor. (1300 aa)
	BCAR3	Breast cancer anti-estrogen resistance protein 3 isoform X1. (835 aa)
	SLC39A14	Zinc transporter ZIP14 isoform X2. (490 aa)
	APC	Adenomatous polyposis coli protein isoform X1. (2844 aa)
	PIK3R3	Phosphatidylinositol 3-kinase regulatory subunit gamma. (507 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	ZNF106	Zinc finger protein 106 isoform X1. (1917 aa)
	PHIP	PH-interacting protein. (1821 aa)
	IRS4	LOW QUALITY PROTEIN: insulin receptor substrate 4. (1307 aa)
	FOXO1	Forkhead box protein O1. (662 aa)
	SMARCC1	SWI/SNF complex subunit SMARCC1. (1050 aa)
	NDEL1	Nuclear distribution protein nudE-like 1 isoform X1. (345 aa)
	PTPRA	Receptor-type tyrosine-protein phosphatase alpha. (813 aa)
	GRB14	Growth factor receptor-bound protein 14 isoform X1. (540 aa)
	FOXO4	Forkhead box protein O4. (509 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	GRB2	Growth factor receptor-bound protein 2 isoform X1. (217 aa)
	PDK4	Protein-serine/threonine kinase. (406 aa)
	EIF4EBP2	Eukaryotic translation initiation factor 4E-binding protein 2. (120 aa)
	SOGA1	Protein SOGA1 isoform X1. (1650 aa)
	SLC2A8	Solute carrier family 2, facilitated glucose transporter member 8 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (478 aa)
	DNAI1	Dynein intermediate chain 1, axonemal. (697 aa)

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	A0A2U3VLF0	A0A2U3VMY7	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.900
AKT1	AKT3	A0A2U3VLF0	A0A2U3VY63	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.917
AKT1	APPL1	A0A2U3VLF0	A0A2U3WDH4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	DCC-interacting protein 13-alpha.	0.819
AKT1	FOXO1	A0A2U3VLF0	A0A2U3VVM3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein O1.	0.969
AKT1	FOXO4	A0A2U3VLF0	A0A2U3VNJ0	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein O4.	0.967
AKT1	GSK3A	A0A2U3VLF0	A0A2U3WHJ5	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Glycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily.	0.953
AKT1	GSK3B	A0A2U3VLF0	A0A2U3W616	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	0.953
AKT1	INS	A0A2U3VLF0	A0A2U3W6R9	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.486
AKT1	PIK3R1	A0A2U3VLF0	A0A2U3X1Z3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.959
AKT1	PIK3R2	A0A2U3VLF0	A0A2U3W8T2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.952
AKT1	PIK3R3	A0A2U3VLF0	A0A2U3VYN3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 3-kinase regulatory subunit gamma.	0.947
AKT2	AKT1	A0A2U3VMY7	A0A2U3VLF0	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.900
AKT2	AKT3	A0A2U3VMY7	A0A2U3VY63	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.917
AKT2	APPL1	A0A2U3VMY7	A0A2U3WDH4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	DCC-interacting protein 13-alpha.	0.819
AKT2	FOXO1	A0A2U3VMY7	A0A2U3VVM3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein O1.	0.969
AKT2	FOXO4	A0A2U3VMY7	A0A2U3VNJ0	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein O4.	0.967
AKT2	GSK3A	A0A2U3VMY7	A0A2U3WHJ5	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Glycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily.	0.953
AKT2	GSK3B	A0A2U3VMY7	A0A2U3W616	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	0.953
AKT2	INS	A0A2U3VMY7	A0A2U3W6R9	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.486
AKT2	PIK3R1	A0A2U3VMY7	A0A2U3X1Z3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.959