STRINGSTRING
PSENEN PSENEN BACE1 BACE1 DYRK1A DYRK1A APH1B APH1B NCSTN NCSTN APH1A APH1A PSEN1 PSEN1 ABCA7 ABCA7 PSEN2 PSEN2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSENENGamma-secretase subunit PEN-2. (101 aa)
BACE1Beta-secretase 1 isoform X1; Belongs to the peptidase A1 family. (501 aa)
DYRK1ADual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1. (763 aa)
APH1BGamma-secretase subunit APH-1B isoform X1. (257 aa)
NCSTNNicastrin isoform X1. (708 aa)
APH1AGamma-secretase subunit APH-1A isoform X1. (265 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
ABCA7ATP-binding cassette sub-family A member 7. (2140 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (464 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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