STRINGSTRING
DYRK1A DYRK1A APH1B APH1B NCSTN NCSTN ADAM10 ADAM10 ABCG1 ABCG1 ADAM19 ADAM19 APH1A APH1A APOE APOE DHCR24 DHCR24 PSEN1 PSEN1 CLN3 CLN3 PSENEN PSENEN ABCA7 ABCA7 LDLRAP1 LDLRAP1 PSEN2 PSEN2 TMCC2 TMCC2 DLG2 DLG2 DLG1 DLG1 LOC101382121 LOC101382121 BACE1 BACE1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DYRK1ADual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1. (763 aa)
APH1BGamma-secretase subunit APH-1B isoform X1. (257 aa)
NCSTNNicastrin isoform X1. (708 aa)
ADAM10Disintegrin and metalloproteinase domain-containing protein 10 isoform X1. (748 aa)
ABCG1ATP-binding cassette sub-family G member 1 isoform X1. (678 aa)
ADAM19Disintegrin and metalloproteinase domain-containing protein 19. (909 aa)
APH1AGamma-secretase subunit APH-1A isoform X1. (265 aa)
APOEApolipoprotein E. (329 aa)
DHCR24Delta(24)-sterol reductase. (516 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
CLN3Battenin. (438 aa)
PSENENGamma-secretase subunit PEN-2. (101 aa)
ABCA7ATP-binding cassette sub-family A member 7. (2140 aa)
LDLRAP1Low density lipoprotein receptor adapter protein 1. (309 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (464 aa)
TMCC2Transmembrane and coiled-coil domains protein 2 isoform X1. (707 aa)
DLG2Disks large homolog 2 isoform X1. (624 aa)
DLG1Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (939 aa)
LOC101382121Neuron-specific protein family member 1. (186 aa)
BACE1Beta-secretase 1 isoform X1; Belongs to the peptidase A1 family. (501 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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