STRINGSTRING
PAFAH1B1 PAFAH1B1 INPP5K INPP5K DUSP8 DUSP8 NLRP6 NLRP6 EFNA1 EFNA1 GBA GBA ASH1L ASH1L SEMA6A SEMA6A PEBP4 PEBP4 ITGB1BP1 ITGB1BP1 RGS14 RGS14 PTPN22 PTPN22 CBLC CBLC APOE APOE C1QL4 C1QL4 NF2 NF2 DUSP2 DUSP2 NF1 NF1 FOXO1 FOXO1 DAG1 DAG1 QARS QARS PIN1 PIN1 GPS2 GPS2 HDAC3 HDAC3 SPRY4 SPRY4 TAOK3 TAOK3 PEBP1 PEBP1 P2RX7 P2RX7 SH2B3 SH2B3 ABCA7 ABCA7 PHB PHB CDK5RAP3 CDK5RAP3 EMILIN1 EMILIN1 PSMD10 PSMD10 SFRP1 SFRP1 SFRP2 SFRP2 SLC9A3R1 SLC9A3R1 GPER1 GPER1 TMEM130 TMEM130 TBC1D10C TBC1D10C LAX1 LAX1 ABL1 ABL1 DUSP1 DUSP1 LOC101372453 LOC101372453 NUP62CL NUP62CL DLG2 DLG2 LOC101371768 LOC101371768 PTPRC PTPRC PAQR3 PAQR3 DUPD1 DUPD1 LOC105757077 LOC105757077 PTPRJ PTPRJ LIF LIF SPRY2 SPRY2 CD300A CD300A NDRG2 NDRG2 TNIP1 TNIP1 RAPGEF1 RAPGEF1 BMP4 BMP4 IGF1R IGF1R ITCH ITCH MECOM MECOM MARVELD3 MARVELD3 MYC MYC LOC101370160 LOC101370160 DUSP7 DUSP7 DAB2IP DAB2IP LOC101371328 LOC101371328 ZMYND11 ZMYND11 HMGCR HMGCR DUSP3 DUSP3 EPHA4 EPHA4 LEMD2 LEMD2 DUSP4 DUSP4 LOC101380941 LOC101380941 DUSP27 DUSP27 DUSP10 DUSP10 PTPN2 PTPN2 CYLD CYLD CAV1 CAV1 DUSP9 DUSP9 SPRED1 SPRED1 PTEN PTEN FKTN FKTN VRK3 VRK3 PRMT1 PRMT1 NUP62 NUP62 SMAD4 SMAD4 KLHL31 KLHL31 DUSP16 DUSP16 DUSP5 DUSP5 PBK PBK DUSP26 DUSP26 FOXM1 FOXM1 PTPN1 PTPN1 CAV3 CAV3 LOC101362978 LOC101362978 SORL1 SORL1 SMPD1 SMPD1 ADIPOQ ADIPOQ F2RL1 F2RL1 PTPN6 PTPN6 PPIA PPIA TIMP3 TIMP3 LYN LYN ATF3 ATF3 DUSP6 DUSP6 NCOR1 NCOR1 SPRY1 SPRY1 DACT1 DACT1 IRAK3 IRAK3 FBLN1 FBLN1 TLR4 TLR4 SPRY3 SPRY3 BMP2 BMP2 BMP7 BMP7 EZR EZR TREM2 TREM2 TREML1 TREML1 LOC101379690 LOC101379690 DLG1 DLG1 SPRED3 SPRED3 SPRED2 SPRED2 DUSP13 DUSP13 PRDM15 PRDM15 PTPRR PTPRR PSCA PSCA FLCN FLCN AGT AGT PIK3R2 PIK3R2 RANBP9 RANBP9
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
INPP5KInositol polyphosphate 5-phosphatase K. (451 aa)
DUSP8Dual specificity protein phosphatase 8. (626 aa)
NLRP6NACHT, LRR and PYD domains-containing protein 6. (892 aa)
EFNA1ephrin-A1 isoform X1; Belongs to the ephrin family. (206 aa)
GBAGlucosylceramidase. (536 aa)
ASH1LHistone-lysine N-methyltransferase ASH1L. (2964 aa)
SEMA6Asemaphorin-6A isoform X1; Belongs to the semaphorin family. (1047 aa)
PEBP4LOW QUALITY PROTEIN: phosphatidylethanolamine-binding protein 4. (323 aa)
ITGB1BP1Integrin beta-1-binding protein 1. (200 aa)
RGS14Regulator of G-protein signaling 14. (567 aa)
PTPN22Tyrosine-protein phosphatase non-receptor type 22 isoform X1. (806 aa)
CBLCE3 ubiquitin-protein ligase CBL-C. (496 aa)
APOEApolipoprotein E. (329 aa)
C1QL4Complement C1q-like protein 4. (238 aa)
NF2Merlin isoform X1. (596 aa)
DUSP2Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (313 aa)
NF1Neurofibromin isoform X1. (2841 aa)
FOXO1Forkhead box protein O1. (662 aa)
DAG1Dystroglycan. (892 aa)
QARSglutamine--tRNA ligase isoform X1; Belongs to the class-I aminoacyl-tRNA synthetase family. (775 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
GPS2G protein pathway suppressor 2 isoform X1. (327 aa)
HDAC3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (428 aa)
SPRY4Protein sprouty homolog 4. (299 aa)
TAOK3Serine/threonine-protein kinase TAO3 isoform X1. (898 aa)
PEBP1Phosphatidylethanolamine-binding protein 1. (187 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (589 aa)
SH2B3SH2B adapter protein 3. (578 aa)
ABCA7ATP-binding cassette sub-family A member 7. (2140 aa)
PHBProhibitin. (272 aa)
CDK5RAP3CDK5 regulatory subunit-associated protein 3 isoform X1. (504 aa)
EMILIN1EMILIN-1. (1015 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
SFRP1Secreted frizzled-related protein 1. (314 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
TMEM130Transmembrane protein 130 isoform X1. (435 aa)
TBC1D10CCarabin. (446 aa)
LAX1Lymphocyte transmembrane adapter 1. (397 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
LOC101372453Nuclear pore glycoprotein p62-like. (365 aa)
NUP62CLNucleoporin-62 C-terminal-like protein. (308 aa)
DLG2Disks large homolog 2 isoform X1. (624 aa)
LOC101371768LOW QUALITY PROTEIN: leukocyte immunoglobulin-like receptor subfamily A member 6. (351 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C. (1302 aa)
PAQR3Progestin and adipoQ receptor family member 3. (311 aa)
DUPD1Dual specificity phosphatase DUPD1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (288 aa)
LOC105757077Synaptojanin-2-binding protein. (145 aa)
PTPRJReceptor-type tyrosine-protein phosphatase eta. (1216 aa)
LIFLeukemia inhibitory factor isoform X1. (204 aa)
SPRY2Protein sprouty homolog 2. (315 aa)
CD300ACMRF35-like molecule 8. (308 aa)
NDRG2Protein NDRG2 isoform X1. (391 aa)
TNIP1TNFAIP3-interacting protein 1 isoform X1. (675 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1270 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
IGF1RTyrosine-protein kinase receptor. (1304 aa)
ITCHE3 ubiquitin-protein ligase. (865 aa)
MECOMMDS1 and EVI1 complex locus protein EVI1 isoform X1. (1230 aa)
MARVELD3MARVEL domain-containing protein 3 isoform X1. (383 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
LOC101370160Toll-like receptor 9 isoform X1. (1056 aa)
DUSP7Dual specificity protein phosphatase 7 isoform X1. (427 aa)
DAB2IPLOW QUALITY PROTEIN: disabled homolog 2-interacting protein. (1338 aa)
LOC101371328LOW QUALITY PROTEIN: folliculin-like. (610 aa)
ZMYND11Zinc finger MYND domain-containing protein 11 isoform X1. (611 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (915 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
EPHA4Ephrin type-A receptor 4 isoform X1. (986 aa)
LEMD2LEM domain-containing protein 2. (535 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
LOC101380941Lymphocyte transmembrane adapter 1-like. (266 aa)
DUSP27Inactive dual specificity phosphatase 27; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (1111 aa)
DUSP10Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (416 aa)
CYLDUbiquitin carboxyl-terminal hydrolase CYLD isoform X1; Belongs to the peptidase C19 family. (956 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
DUSP9Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (380 aa)
SPRED1Sprouty-related, EVH1 domain-containing protein 1. (442 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
FKTNFukutin. (461 aa)
VRK3Inactive serine/threonine-protein kinase VRK3. (489 aa)
PRMT1Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
NUP62Nuclear pore glycoprotein p62. (532 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
KLHL31Kelch-like protein 31. (634 aa)
DUSP16Dual specificity protein phosphatase 16. (666 aa)
DUSP5Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
PBKLymphokine-activated killer T-cell-originated protein kinase isoform X1. (323 aa)
DUSP26Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (211 aa)
FOXM1Forkhead box protein M1 isoform X1. (763 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (427 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
LOC101362978Protein C3orf33 homolog. (250 aa)
SORL1Sortilin-related receptor. (2211 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (625 aa)
ADIPOQAdiponectin isoform X1. (266 aa)
F2RL1Proteinase-activated receptor 2. (398 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
PPIAPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (164 aa)
TIMP3Metalloproteinase inhibitor 3 isoform X1. (211 aa)
LYNTyrosine-protein kinase. (512 aa)
ATF3Cyclic AMP-dependent transcription factor ATF-3. (181 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
NCOR1Nuclear receptor corepressor 1 isoform X1. (2434 aa)
SPRY1Protein sprouty homolog 1. (319 aa)
DACT1Dapper homolog 1 isoform X1. (845 aa)
IRAK3Interleukin-1 receptor-associated kinase 3. (614 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (705 aa)
TLR4Toll-like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
SPRY3Protein sprouty homolog 3. (288 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
EZREzrin isoform X1. (584 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (226 aa)
TREML1Trem-like transcript 1 protein isoform X1. (311 aa)
LOC101379690Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (427 aa)
DLG1Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (939 aa)
SPRED3Sprouty-related, EVH1 domain-containing protein 3 isoform X1. (435 aa)
SPRED2Sprouty-related, EVH1 domain-containing protein 2 isoform X1. (431 aa)
DUSP13Dual specificity protein phosphatase 13 isoform X1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (327 aa)
PRDM15PR domain zinc finger protein 15. (1176 aa)
PTPRRReceptor-type tyrosine-protein phosphatase R isoform X1. (655 aa)
PSCAProstate stem cell antigen. (301 aa)
FLCNFolliculin. (579 aa)
AGTAngiotensinogen; Belongs to the serpin family. (477 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa)
RANBP9Ran-binding protein 9. (679 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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