STRINGSTRING
PLCG2 PLCG2 CDH13 CDH13 ATP2B4 ATP2B4 SLA2 SLA2 TBC1D10C TBC1D10C ACTN3 ACTN3 SLC24A4 SLC24A4 SLC9A1 SLC9A1 P2RX4 P2RX4 HTT HTT CMKLR1 CMKLR1 SPPL3 SPPL3 EFHB EFHB PRNP PRNP CIB1 CIB1 HOMER2 HOMER2 CHP2 CHP2 ZAP70 ZAP70 SLC8A2 SLC8A2 GPR143 GPR143 MYOZ2 MYOZ2 ERBB3 ERBB3 LRRK2 LRRK2 HN1L HN1L GSK3B GSK3B HOMER3 HOMER3 CHERP CHERP TMEM100 TMEM100 CMYA5 CMYA5 MYOZ1 MYOZ1 LOC101376353 LOC101376353 RCAN1 RCAN1 SYK SYK LOC101380816 LOC101380816 BST1 BST1 MTOR MTOR PTK2B PTK2B LOC101370944 LOC101370944 FHL2 FHL2 LMCD1 LMCD1 ADA ADA PPP3R2 PPP3R2 CD3E CD3E TNF TNF TMBIM4 TMBIM4 DYRK2 DYRK2 TREM2 TREM2 TREML1 TREML1 PDK2 PDK2 ITPR1 ITPR1 MAPK7 MAPK7 MYH7B MYH7B LOC101371432 LOC101371432 LOC101386919 LOC101386919
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
CDH13Cadherin-13 isoform X1. (713 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1242 aa)
SLA2Src-like-adapter 2. (276 aa)
TBC1D10CCarabin. (446 aa)
ACTN3Alpha-actinin-3 isoform X1. (907 aa)
SLC24A4Sodium/potassium/calcium exchanger 4 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (622 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa)
HTTHuntingtin. (3130 aa)
CMKLR1Chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
SPPL3Signal peptide peptidase-like 3. (384 aa)
EFHBEF-hand domain-containing family member B. (878 aa)
PRNPMajor prion protein; Belongs to the prion family. (257 aa)
CIB1Calcium and integrin-binding protein 1. (191 aa)
HOMER2Homer protein homolog 2 isoform X1. (343 aa)
CHP2Calcineurin B homologous protein 2. (196 aa)
ZAP70Tyrosine-protein kinase ZAP-70; Belongs to the protein kinase superfamily. Tyr protein kinase family. (326 aa)
SLC8A2Sodium/calcium exchanger 2 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
GPR143G-protein coupled receptor 143. (413 aa)
MYOZ2Myozenin-2. (264 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1339 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2 isoform X1. (2526 aa)
HN1LHematological and neurological expressed 1-like protein. (190 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
HOMER3Homer protein homolog 3 isoform X1. (359 aa)
CHERPCalcium homeostasis endoplasmic reticulum protein. (872 aa)
TMEM100Transmembrane protein 100. (134 aa)
CMYA5Cardiomyopathy-associated protein 5. (3985 aa)
MYOZ1Myozenin-1. (297 aa)
LOC101376353Uncharacterized protein C10orf71 homolog. (1401 aa)
RCAN1Calcipressin-1 isoform X1. (249 aa)
SYKTyrosine-protein kinase. (635 aa)
LOC101380816Sialic acid-binding Ig-like lectin 10 isoform X1. (689 aa)
BST1LOW QUALITY PROTEIN: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2. (312 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2559 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
LOC101370944C-C motif chemokine. (93 aa)
FHL2Four and a half LIM domains protein 2. (279 aa)
LMCD1LIM and cysteine-rich domains protein 1 isoform X1. (363 aa)
ADAAdenosine deaminase. (363 aa)
PPP3R2Calcineurin subunit B type 2. (170 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain. (190 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
TMBIM4Protein lifeguard 4 isoform X1; Belongs to the BI1 family. (238 aa)
DYRK2Dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X1. (601 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (226 aa)
TREML1Trem-like transcript 1 protein isoform X1. (311 aa)
PDK2Protein-serine/threonine kinase. (423 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2758 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (806 aa)
MYH7Bmyosin-7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa)
LOC101371432T-cell receptor-associated transmembrane adapter 1. (217 aa)
LOC101386919Transmembrane protein 110. (294 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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