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HNRNPU HNRNPU SF3B3 SF3B3 PPIL3 PPIL3 SF3B1 SF3B1 SART1 SART1 BUD31 BUD31 PLRG1 PLRG1 SYF2 SYF2 HNRNPR HNRNPR SF3B6 SF3B6 AMH AMH LSM7 LSM7 SF3A2 SF3A2 CACTIN CACTIN WDR25 WDR25 LSM3 LSM3 ISY1 ISY1 ZCCHC8 ZCCHC8 LOC101369390 LOC101369390 LOC101375442 LOC101375442 SNRPB SNRPB RBM8A RBM8A LOC101373629 LOC101373629 SNRPG SNRPG WDR83 WDR83 SNW1 SNW1 PNN PNN SNRNP200 SNRNP200 SF3A1 SF3A1 SNRPF SNRPF MAGOH MAGOH PPIL2 PPIL2 BTBD19 BTBD19 DDX23 DDX23 SNRPD2 SNRPD2 BCAS2 BCAS2 DDX41 DDX41 PPWD1 PPWD1 CWC27 CWC27 PABPC1 PABPC1 PPIE PPIE RBM22 RBM22 CWC22 CWC22 EIF4A3 EIF4A3 SLU7 SLU7 SRSF1 SRSF1 GPATCH1 GPATCH1 SNRPA1 SNRPA1 SNRNP40 SNRNP40 CDC40 CDC40 DHX8 DHX8 LOC101378288 LOC101378288 SYNCRIP SYNCRIP AQR AQR PPIL1 PPIL1 PRPF19 PRPF19 PRPF6 PRPF6 RBM44 RBM44 MAGOHB MAGOHB SNRPD1 SNRPD1 XAB2 XAB2 CWC15 CWC15 TFIP11 TFIP11 LOC101376578 LOC101376578 PRPF4B PRPF4B LSM2 LSM2 DHX35 DHX35 LOC101369699 LOC101369699 SNRPN SNRPN SNRPB2 SNRPB2 SKIV2L2 SKIV2L2 CDC5L CDC5L SRRM1 SRRM1 LOC101376975 LOC101376975 SNRPD3 SNRPD3 SF3A3 SF3A3 SRRM2 SRRM2 PRPF8 PRPF8 DDX5 DDX5 EFTUD2 EFTUD2 DHX38 DHX38 RBMX RBMX CRNKL1 CRNKL1 EIF4A2 EIF4A2 SF3B2 SF3B2 LOC101376302 LOC101376302 DGCR14 DGCR14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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HNRNPUHeterogeneous nuclear ribonucleoprotein U isoform X1. (825 aa)
SF3B3Splicing factor 3B subunit 3. (1217 aa)
PPIL3Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (161 aa)
SF3B1Splicing factor 3B subunit 1 isoform X1. (1304 aa)
SART1U4/U6.U5 tri-snRNP-associated protein 1 isoform X1. (806 aa)
BUD31Protein BUD31 homolog. (144 aa)
PLRG1Pleiotropic regulator 1 isoform X1. (515 aa)
SYF2pre-mRNA-splicing factor SYF2. (246 aa)
HNRNPRHeterogeneous nuclear ribonucleoprotein R isoform X1. (633 aa)
SF3B6Splicing factor 3B subunit 6. (125 aa)
AMHMuellerian-inhibiting factor. (578 aa)
LSM7U6 snRNA-associated Sm-like protein LSm7. (103 aa)
SF3A2Splicing factor 3A subunit 2. (471 aa)
CACTINCactin. (750 aa)
WDR25WD repeat-containing protein 25. (539 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
ISY1pre-mRNA-splicing factor ISY1 homolog. (285 aa)
ZCCHC8Zinc finger CCHC domain-containing protein 8. (709 aa)
LOC101369390UPF0692 protein C19orf54 homolog. (348 aa)
LOC101375442Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
LOC101373629Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (123 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
WDR83WD repeat domain-containing protein 83. (315 aa)
SNW1SNW domain-containing protein 1 isoform X1. (536 aa)
PNNPinin isoform X1. (753 aa)
SNRNP200U5 small nuclear ribonucleoprotein 200 kDa helicase. (2136 aa)
SF3A1Splicing factor 3A subunit 1. (793 aa)
SNRPFSmall nuclear ribonucleoprotein F. (86 aa)
MAGOHProtein mago nashi homolog. (146 aa)
PPIL2Peptidyl-prolyl cis-trans isomerase-like 2 isoform X1. (522 aa)
BTBD19BTB/POZ domain-containing protein 19. (291 aa)
DDX23Probable ATP-dependent RNA helicase DDX23. (820 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
BCAS2pre-mRNA-splicing factor SPF27. (225 aa)
DDX41Probable ATP-dependent RNA helicase DDX41 isoform X1. (622 aa)
PPWD1Peptidylprolyl isomerase domain and WD repeat-containing protein 1 isoform X1. (646 aa)
CWC27Peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform X1. (472 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
RBM22pre-mRNA-splicing factor RBM22. (419 aa)
CWC22pre-mRNA-splicing factor CWC22 homolog isoform X1. (908 aa)
EIF4A3Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (411 aa)
SLU7pre-mRNA-splicing factor SLU7. (633 aa)
SRSF1Serine/arginine-rich splicing factor 1. (248 aa)
GPATCH1G patch domain-containing protein 1. (932 aa)
SNRPA1U2 small nuclear ribonucleoprotein A. (255 aa)
SNRNP40U5 small nuclear ribonucleoprotein 40 kDa protein. (358 aa)
CDC40pre-mRNA-processing factor 17. (579 aa)
DHX8ATP-dependent RNA helicase DHX8. (1220 aa)
LOC101378288Dentin sialophosphoprotein-like. (1380 aa)
SYNCRIPHeterogeneous nuclear ribonucleoprotein Q isoform X1. (623 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1491 aa)
PPIL1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
PRPF19pre-mRNA-processing factor 19. (504 aa)
PRPF6pre-mRNA-processing factor 6 isoform X1. (941 aa)
RBM44RNA-binding protein 44. (1052 aa)
MAGOHBProtein mago nashi homolog 2 isoform X1. (148 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
XAB2pre-mRNA-splicing factor SYF1. (855 aa)
CWC15Spliceosome-associated protein CWC15 homolog. (231 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa)
LOC101376578Small nuclear ribonucleoprotein F-like. (86 aa)
PRPF4BSerine/threonine-protein kinase PRP4 homolog. (1041 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
DHX35Probable ATP-dependent RNA helicase DHX35 isoform X1. (708 aa)
LOC101369699RNA-binding motif protein, X chromosome-like. (391 aa)
SNRPNSmall nuclear ribonucleoprotein-associated protein. (240 aa)
SNRPB2U2 small nuclear ribonucleoprotein B'' isoform X1. (225 aa)
SKIV2L2Superkiller viralicidic activity 2-like 2 isoform X1. (1042 aa)
CDC5LCell division cycle 5-like protein isoform X1. (802 aa)
SRRM1Serine/arginine repetitive matrix protein 1. (783 aa)
LOC101376975pre-mRNA-splicing factor SYF2-like. (265 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
SF3A3Splicing factor 3A subunit 3 isoform X1. (583 aa)
SRRM2Serine/arginine repetitive matrix protein 2. (195 aa)
PRPF8pre-mRNA-processing-splicing factor 8. (2335 aa)
DDX5Probable ATP-dependent RNA helicase DDX5 isoform X1; Belongs to the DEAD box helicase family. (614 aa)
EFTUD2116 kDa U5 small nuclear ribonucleoprotein component isoform X1. (972 aa)
DHX38pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16. (1239 aa)
RBMXRNA-binding motif protein, X chromosome isoform X1. (391 aa)
CRNKL1LOW QUALITY PROTEIN: crooked neck-like protein 1. (829 aa)
EIF4A2Eukaryotic initiation factor 4A-II isoform X1; Belongs to the DEAD box helicase family. (408 aa)
SF3B2Splicing factor 3B subunit 2 isoform X1. (896 aa)
LOC101376302LOW QUALITY PROTEIN: serine/arginine repetitive matrix protein 1-like. (911 aa)
DGCR14Protein DGCR14 isoform X1. (478 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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