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ADRB3 ADRB3 CHGA CHGA ADRA2C ADRA2C PLN PLN ADRA1D ADRA1D ADRA2B ADRA2B ADRB2 ADRB2 ADCY9 ADCY9 DRD4 DRD4 ADRA1B ADRA1B GPR101 GPR101 ADRA2A ADRA2A ADRB1 ADRB1 ADRA1A ADRA1A CHRM3 CHRM3 GNAS GNAS DRD1 DRD1 DRD3 DRD3 DRD5 DRD5 RAPGEF2 RAPGEF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADRB3Beta-3 adrenergic receptor. (408 aa)
CHGAchromogranin-A isoform X1. (445 aa)
ADRA2Calpha-2C adrenergic receptor. (474 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
ADRA1Dalpha-1D adrenergic receptor. (569 aa)
ADRA2Balpha-2B adrenergic receptor. (443 aa)
ADRB2Beta-2 adrenergic receptor. (418 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
DRD4D(4) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (362 aa)
ADRA1Balpha-1B adrenergic receptor. (518 aa)
GPR101Probable G-protein coupled receptor 101; Belongs to the G-protein coupled receptor 1 family. (492 aa)
ADRA2Aalpha-2A adrenergic receptor. (465 aa)
ADRB1Beta-1 adrenergic receptor. (468 aa)
ADRA1Aalpha-1A adrenergic receptor. (465 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1015 aa)
DRD1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (446 aa)
DRD3D(3) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (400 aa)
DRD5D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (474 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2 isoform X1. (1644 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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