52 items (Odobenus rosmarus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRKAA1	Non-specific serine/threonine protein kinase. (528 aa)
	SPHK2	Sphingosine kinase 2 isoform X1. (659 aa)
	GRAMD1B	GRAM domain-containing protein 1B isoform X1. (881 aa)
	LOC101385942	Golgi phosphoprotein 3-like. (236 aa)
	LARP1	La-related protein 1 isoform X1. (1102 aa)
	ADCY1	Adenylate cyclase type 1. (907 aa)
	ADCY7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
	LOC101364116	LOW QUALITY PROTEIN: dynactin-associated protein-like. (360 aa)
	ADAM15	Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (867 aa)
	ADCY6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
	SPIDR	DNA repair-scaffolding protein. (794 aa)
	ADCY5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
	NFE2L1	Nuclear factor erythroid 2-related factor 1 isoform X1. (778 aa)
	CTNNB1	Catenin beta-1 isoform X1. (781 aa)
	GRAMD1A	GRAM domain-containing protein 1A isoform X1. (723 aa)
	ACACB	acetyl-CoA carboxylase 2. (2456 aa)
	PTGER2	Prostaglandin E2 receptor EP2 subtype; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	GRAMD1C	GRAM domain-containing protein 1C isoform X1. (669 aa)
	PRKAA2	Non-specific serine/threonine protein kinase. (552 aa)
	PTGFR	Prostaglandin F2-alpha receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
	GOLPH3	Golgi phosphoprotein 3. (298 aa)
	LRP6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	TP53INP1	Tumor protein p53-inducible nuclear protein 1 isoform X1. (239 aa)
	JUP	Junction plakoglobin. (744 aa)
	GLRA2	Glycine receptor subunit alpha-2 isoform X2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
	MLC1	Membrane protein MLC1. (373 aa)
	TNFSF4	Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa)
	PTGER4	Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (489 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1483 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	PTCH1	Protein patched homolog 1 isoform X1. (1452 aa)
	GPLD1	Phosphatidylinositol-glycan-specific phospholipase D. (843 aa)
	CREB1	Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
	PRKCE	Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
	GLRA1	Glycine receptor subunit alpha-1 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
	FDX1	Adrenodoxin, mitochondrial. (178 aa)
	RAD51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
	AHR	Aryl hydrocarbon receptor. (845 aa)
	SCNN1G	Amiloride-sensitive sodium channel subunit gamma; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (646 aa)
	BLM	Bloom syndrome protein isoform X1. (1428 aa)
	SMO	Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
	ACACA	acetyl-CoA carboxylase 1 isoform X1. (2385 aa)
	P2RY4	P2Y purinoceptor 4; Belongs to the G-protein coupled receptor 1 family. (365 aa)
	MAP4K1	Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa)
	OSBPL7	Oxysterol-binding protein; Belongs to the OSBP family. (842 aa)
	PTRHD1	Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
	ADCY3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
	SFRP1	Secreted frizzled-related protein 1. (314 aa)
	RECQL5	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (985 aa)
	NPAS4	Neuronal PAS domain-containing protein 4. (800 aa)
	EFNA5	ephrin-A5; Belongs to the ephrin family. (228 aa)
	P2RY6	P2Y purinoceptor 6. (398 aa)

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACACA	ACACB	A0A2U3VRJ8	A0A2U3X286	acetyl-CoA carboxylase 1 isoform X1.	acetyl-CoA carboxylase 2.	0.901
ACACA	PRKAA1	A0A2U3VRJ8	A0A2U3WK21	acetyl-CoA carboxylase 1 isoform X1.	Non-specific serine/threonine protein kinase.	0.924
ACACA	PRKAA2	A0A2U3VRJ8	A0A2U3WYR5	acetyl-CoA carboxylase 1 isoform X1.	Non-specific serine/threonine protein kinase.	0.924
ACACB	ACACA	A0A2U3X286	A0A2U3VRJ8	acetyl-CoA carboxylase 2.	acetyl-CoA carboxylase 1 isoform X1.	0.901
ACACB	PRKAA1	A0A2U3X286	A0A2U3WK21	acetyl-CoA carboxylase 2.	Non-specific serine/threonine protein kinase.	0.924
ACACB	PRKAA2	A0A2U3X286	A0A2U3WYR5	acetyl-CoA carboxylase 2.	Non-specific serine/threonine protein kinase.	0.924
ADCY1	ADCY3	A0A2U3ZPU3	A0A2U3VJB8	Adenylate cyclase type 1.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.947
ADCY1	ADCY5	A0A2U3ZPU3	A0A2U3ZBK5	Adenylate cyclase type 1.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.500
ADCY1	ADCY6	A0A2U3ZPU3	A0A2U3ZH57	Adenylate cyclase type 1.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.502
ADCY1	ADCY7	A0A2U3ZPU3	A0A2U3ZP39	Adenylate cyclase type 1.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.632
ADCY1	GNG2	A0A2U3ZPU3	A0A2U3WH94	Adenylate cyclase type 1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.828
ADCY1	PTRHD1	A0A2U3ZPU3	A0A2U3VJC4	Adenylate cyclase type 1.	Putative peptidyl-tRNA hydrolase PTRHD1.	0.457
ADCY3	ADCY1	A0A2U3VJB8	A0A2U3ZPU3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1.	0.947
ADCY3	ADCY5	A0A2U3VJB8	A0A2U3ZBK5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.517
ADCY3	ADCY6	A0A2U3VJB8	A0A2U3ZH57	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.950
ADCY3	ADCY7	A0A2U3VJB8	A0A2U3ZP39	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.513
ADCY3	GNG2	A0A2U3VJB8	A0A2U3WH94	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.825
ADCY5	ADCY1	A0A2U3ZBK5	A0A2U3ZPU3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1.	0.500
ADCY5	ADCY3	A0A2U3ZBK5	A0A2U3VJB8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.517
ADCY5	ADCY6	A0A2U3ZBK5	A0A2U3ZH57	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.950