STRINGSTRING
MAPK10 MAPK10 PAK1 PAK1 TNK2 TNK2 PAK2 PAK2 STK10 STK10 MELK MELK CDK9 CDK9 CSNK2A1 CSNK2A1 DSTYK DSTYK PLK4 PLK4 PSKH2 PSKH2 MAP4K2 MAP4K2 RPS6KA4 RPS6KA4 RPS6KA5 RPS6KA5 STK33 STK33 RPS6KA1 RPS6KA1 CDK12 CDK12 MAP2K2 MAP2K2 MKNK2 MKNK2 AKT1 AKT1 PRKDC PRKDC CSNK2A2 CSNK2A2 IRAK4 IRAK4 CDK13 CDK13 AKT2 AKT2 MAP3K10 MAP3K10 MAP4K1 MAP4K1 PAK4 PAK4 CIT CIT PIM2 PIM2 SBK1 SBK1 MAPK3 MAPK3 AAK1 AAK1 LOC101368513 LOC101368513 RPS6KB1 RPS6KB1 PRKCQ PRKCQ PIK3CA PIK3CA PLK1 PLK1 PRKCB PRKCB CCDC151 CCDC151 PRKACA PRKACA MAPKAPK3 MAPKAPK3 FBXW12 FBXW12 NLK NLK PAK3 PAK3 PRKD1 PRKD1 LIMK2 LIMK2 AKT3 AKT3 MAPK1 MAPK1 MKNK1 MKNK1 MAPK15 MAPK15 STK26 STK26 SGK1 SGK1 RPS6KA3 RPS6KA3 CDK4 CDK4 ROCK2 ROCK2 STK40 STK40 CAMK2A CAMK2A PRKCE PRKCE GSK3B GSK3B MAP3K7 MAP3K7 SBK3 SBK3 TMEM248 TMEM248 RIOK1 RIOK1 MAP2K6 MAP2K6 CDK1 CDK1 MAP3K12 MAP3K12 CAMK2D CAMK2D PRKG2 PRKG2 PRKCZ PRKCZ CLK3 CLK3 MAP4K5 MAP4K5 TTBK1 TTBK1 LOC101386222 LOC101386222 LOC101365627 LOC101365627 CDK5 CDK5 IRAK1 IRAK1 LOC101384822 LOC101384822 CSNK1G1 CSNK1G1 PRKCG PRKCG MAPK11 MAPK11 MAPK12 MAPK12 PIM3 PIM3 LOC101371318 LOC101371318 MAPK13 MAPK13 MAPK14 MAPK14 PIM1 PIM1 MAP4K3 MAP4K3 CNTD1 CNTD1 MTOR MTOR PINK1 PINK1 PRKCH PRKCH NEK10 NEK10 PIK3CG PIK3CG MAPK9 MAPK9 PIK3CB PIK3CB PRKACB PRKACB RPS6KA6 RPS6KA6 RIOK3 RIOK3 CAMK2B CAMK2B STK4 STK4 PRPF4B PRPF4B MAP2K1 MAP2K1 PRKAA2 PRKAA2 PAK7 PAK7 TSSK1B TSSK1B IKBKB IKBKB PRKCA PRKCA GSG2 GSG2 MAP3K9 MAP3K9 ANKK1 ANKK1 AURKA AURKA VRK1 VRK1 MAP3K8 MAP3K8 RAF1 RAF1 AURKB AURKB PKN1 PKN1 CDK10 CDK10 DCLK1 DCLK1 PRKD2 PRKD2 CDK2 CDK2 RPS6KA2 RPS6KA2 MAPK7 MAPK7 MAP3K13 MAP3K13 CAMK2G CAMK2G MAPK8 MAPK8 PRKCI PRKCI ROCK1 ROCK1 PSKH1 PSKH1 PRKCD PRKCD STK25 STK25 STK19 STK19 MAP3K11 MAP3K11 RIPK2 RIPK2 PCK1 PCK1 LOC101371373 LOC101371373 RPS6KB2 RPS6KB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK10Mitogen-activated protein kinase. (464 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
TNK2Activated CDC42 kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1080 aa)
PAK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
STK10Serine/threonine-protein kinase 10. (967 aa)
MELKNon-specific serine/threonine protein kinase. (650 aa)
CDK9Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. (488 aa)
CSNK2A1Casein kinase II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (391 aa)
DSTYKDual serine/threonine and tyrosine protein kinase isoform X1. (929 aa)
PLK4Serine/threonine-protein kinase PLK4 isoform X1. (970 aa)
PSKH2Serine/threonine-protein kinase H2; Belongs to the protein kinase superfamily. (385 aa)
MAP4K2Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa)
RPS6KA4Ribosomal protein S6 kinase. (772 aa)
RPS6KA5Ribosomal protein S6 kinase. (798 aa)
STK33Serine/threonine-protein kinase 33. (521 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
CDK12Cyclin-dependent kinase 12 isoform X1. (1490 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
MKNK2MAP kinase-interacting serine/threonine-protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. (484 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PRKDCDNA-dependent protein kinase catalytic subunit isoform X1; Belongs to the PI3/PI4-kinase family. (4136 aa)
CSNK2A2Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (350 aa)
IRAK4Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa)
CDK13Cyclin-dependent kinase 13 isoform X1. (1514 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (934 aa)
MAP4K1Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa)
PAK4Non-specific serine/threonine protein kinase. (595 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2069 aa)
PIM2Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (311 aa)
SBK1Serine/threonine-protein kinase SBK1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (424 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
AAK1AP2-associated protein kinase 1. (962 aa)
LOC101368513Uncharacterized protein FLJ45252-like. (462 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
CCDC151Coiled-coil domain-containing protein 151 isoform X1. (595 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
MAPKAPK3MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
FBXW12F-box/WD repeat-containing protein 12. (465 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
PAK3Serine/threonine-protein kinase PAK 3 isoform X1. (580 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (912 aa)
LIMK2LIM domain kinase 2 isoform X1. (638 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
MKNK1MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (421 aa)
MAPK15Mitogen-activated protein kinase. (559 aa)
STK26Serine/threonine-protein kinase 26 isoform X1. (416 aa)
SGK1Non-specific serine/threonine protein kinase. (526 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
CDK4Cyclin-dependent kinase 4 isoform X1; Belongs to the protein kinase superfamily. (340 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
STK40Serine/threonine-protein kinase 40. (435 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
SBK3Uncharacterized serine/threonine-protein kinase SBK3; Belongs to the protein kinase superfamily. (362 aa)
TMEM248Transmembrane protein 248. (314 aa)
RIOK1Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (568 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
CDK1Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily. (297 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (892 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta. (477 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (591 aa)
CLK3Dual specificity protein kinase CLK3; Belongs to the protein kinase superfamily. (490 aa)
MAP4K5Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (846 aa)
TTBK1Tau-tubulin kinase 1. (1315 aa)
LOC101386222cGMP-dependent protein kinase 1; Belongs to the protein kinase superfamily. (471 aa)
LOC101365627Mitogen-activated protein kinase kinase kinase. (1043 aa)
CDK5Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa)
IRAK1Interleukin-1 receptor-associated kinase 1 isoform X1. (724 aa)
LOC101384822Uncharacterized protein LOC101384822. (336 aa)
CSNK1G1Casein kinase I isoform gamma-1 isoform X1; Belongs to the protein kinase superfamily. (459 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
PIM3Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (326 aa)
LOC101371318cGMP-dependent protein kinase 1-like. (213 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa)
MAP4K3Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (894 aa)
CNTD1Cyclin N-terminal domain-containing protein 1. (329 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2559 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (582 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
NEK10Serine/threonine-protein kinase Nek10. (1173 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1121 aa)
MAPK9Mitogen-activated protein kinase. (427 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa)
RPS6KA6Ribosomal protein S6 kinase. (744 aa)
RIOK3Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (519 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (542 aa)
STK4Serine/threonine-protein kinase 4 isoform X1. (487 aa)
PRPF4BSerine/threonine-protein kinase PRP4 homolog. (1041 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
PAK7Serine/threonine-protein kinase PAK 7. (535 aa)
TSSK1BTestis-specific serine/threonine-protein kinase 1; Belongs to the protein kinase superfamily. (369 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
GSG2Serine/threonine-protein kinase haspin. (768 aa)
MAP3K9Mitogen-activated protein kinase kinase kinase. (1101 aa)
ANKK1LOW QUALITY PROTEIN: ankyrin repeat and protein kinase domain-containing protein 1. (756 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (405 aa)
VRK1Serine/threonine-protein kinase VRK1 isoform X1; Belongs to the protein kinase superfamily. (396 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
AURKBAurora kinase B isoform X1; Belongs to the protein kinase superfamily. (354 aa)
PKN1Serine/threonine-protein kinase N1 isoform X1. (956 aa)
CDK10Cyclin-dependent kinase 10 isoform X1; Belongs to the protein kinase superfamily. (446 aa)
DCLK1Serine/threonine-protein kinase DCLK1 isoform X1. (741 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (877 aa)
CDK2Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (806 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1. (568 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (627 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa)
PSKH1Serine/threonine-protein kinase H1 isoform X1; Belongs to the protein kinase superfamily. (472 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa)
STK25Serine/threonine-protein kinase 25 isoform X1. (352 aa)
STK19Serine/threonine-protein kinase 19 isoform X1. (288 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (901 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP] isoform X1. (622 aa)
LOC101371373Serine/threonine-protein kinase ULK4-like. (238 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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