16 items (Odobenus rosmarus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C1QA	Complement C1q subcomponent subunit A. (245 aa)
	TYROBP	TYRO protein tyrosine kinase-binding protein isoform X1. (111 aa)
	JUN	Transcription factor AP-1 isoform X1; Belongs to the bZIP family. (335 aa)
	SMO	Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (801 aa)
	CNTF	Ciliary neurotrophic factor. (199 aa)
	ADCY8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
	CX3CR1	CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (356 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
	S100B	Protein S100; Belongs to the S-100 family. (92 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (226 aa)
	TREML1	Trem-like transcript 1 protein isoform X1. (311 aa)
	C5AR1	C5a anaphylatoxin chemotactic receptor 1; Belongs to the G-protein coupled receptor 1 family. (330 aa)
	ADCY1	Adenylate cyclase type 1. (907 aa)
	AGER	Advanced glycosylation end product-specific receptor isoform X1. (381 aa)

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY8	A0A2U3ZPU3	A0A2U3WLQ4	Adenylate cyclase type 1.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.952
ADCY8	ADCY1	A0A2U3WLQ4	A0A2U3ZPU3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1.	0.952
AGER	S100B	A0A2U3ZWZ6	A0A2U3X2C1	Advanced glycosylation end product-specific receptor isoform X1.	Protein S100; Belongs to the S-100 family.	0.957
C1QA	CX3CR1	A0A2U3VIZ4	A0A2U3WSF0	Complement C1q subcomponent subunit A.	CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.461
C1QA	TREM2	A0A2U3VIZ4	A0A2U3X4C9	Complement C1q subcomponent subunit A.	Triggering receptor expressed on myeloid cells 2.	0.446
C1QA	TREML1	A0A2U3VIZ4	A0A2U3X4Q9	Complement C1q subcomponent subunit A.	Trem-like transcript 1 protein isoform X1.	0.446
C1QA	TYROBP	A0A2U3VIZ4	A0A2U3VN63	Complement C1q subcomponent subunit A.	TYRO protein tyrosine kinase-binding protein isoform X1.	0.476
CNTF	SMO	A0A2U3WKE1	A0A2U3VS29	Ciliary neurotrophic factor.	Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family.	0.620
CX3CR1	C1QA	A0A2U3WSF0	A0A2U3VIZ4	CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	Complement C1q subcomponent subunit A.	0.461
CX3CR1	IFNG	A0A2U3WSF0	A0A2U3X2V9	CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.536
CX3CR1	TNF	A0A2U3WSF0	A0A2U3X072	CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.538
CX3CR1	TREM2	A0A2U3WSF0	A0A2U3X4C9	CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	Triggering receptor expressed on myeloid cells 2.	0.491
CX3CR1	TREML1	A0A2U3WSF0	A0A2U3X4Q9	CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	Trem-like transcript 1 protein isoform X1.	0.576
CX3CR1	TYROBP	A0A2U3WSF0	A0A2U3VN63	CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	TYRO protein tyrosine kinase-binding protein isoform X1.	0.435
IFNG	CX3CR1	A0A2U3X2V9	A0A2U3WSF0	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.536
IFNG	ITGB1	A0A2U3X2V9	A0A2U3W1L0	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Integrin beta; Belongs to the integrin beta chain family.	0.437
IFNG	JUN	A0A2U3X2V9	A0A2U3WZD8	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Transcription factor AP-1 isoform X1; Belongs to the bZIP family.	0.527
IFNG	TNF	A0A2U3X2V9	A0A2U3X072	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.854
IFNG	TREM2	A0A2U3X2V9	A0A2U3X4C9	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Triggering receptor expressed on myeloid cells 2.	0.485
ITGB1	IFNG	A0A2U3W1L0	A0A2U3X2V9	Integrin beta; Belongs to the integrin beta chain family.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.437