STRINGSTRING
P2RY6 P2RY6 AVPR1B AVPR1B GPER1 GPER1 ERLIN2 ERLIN2 DKK3 DKK3 PTH PTH DGKQ DGKQ H6PD H6PD FGF1 FGF1 SCAP SCAP SEC14L4 SEC14L4 SEC14L2 SEC14L2 SEC14L3 SEC14L3 APOE APOE LOC101363421 LOC101363421 ERLIN1 ERLIN1 BMP5 BMP5 GFI1 GFI1 LHCGR LHCGR SREBF1 SREBF1 APOB APOB BMP6 BMP6 PTK2B PTK2B ABCG4 ABCG4 POU1F1 POU1F1 LPCAT3 LPCAT3 BMP2 BMP2 REST REST PLEK PLEK SEC14L5 SEC14L5 CLCN2 CLCN2 LOC101369154 LOC101369154
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
P2RY6P2Y purinoceptor 6. (398 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (420 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
ERLIN2Erlin-2. (337 aa)
DKK3Dickkopf-related protein 3. (348 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
DGKQDiacylglycerol kinase. (946 aa)
H6PDGDH/6PGL endoplasmic bifunctional protein. (804 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
SCAPSterol regulatory element-binding protein cleavage-activating protein. (1280 aa)
SEC14L4SEC14-like protein 4 isoform X1. (406 aa)
SEC14L2SEC14-like protein 2 isoform X1. (403 aa)
SEC14L3SEC14-like protein 3 isoform X1. (400 aa)
APOEApolipoprotein E. (329 aa)
LOC10136342125-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (508 aa)
ERLIN1Erlin-1. (348 aa)
BMP5Bone morphogenetic protein 5 isoform X1. (454 aa)
GFI1Zinc finger protein Gfi-1. (423 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (695 aa)
SREBF1Sterol regulatory element-binding protein 1 isoform X1. (1187 aa)
APOBApolipoprotein B-100. (4435 aa)
BMP6Bone morphogenetic protein 6. (505 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
ABCG4ATP-binding cassette sub-family G member 4. (646 aa)
POU1F1POU domain protein. (317 aa)
LPCAT3Lysophospholipid acyltransferase 5; Belongs to the membrane-bound acyltransferase family. (487 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
RESTRE1-silencing transcription factor. (1000 aa)
PLEKPleckstrin isoform X1. (351 aa)
SEC14L5SEC14-like protein 5 isoform X1. (721 aa)
CLCN2Chloride channel protein. (903 aa)
LOC101369154Cytochrome P450 27C1 isoform X1; Belongs to the cytochrome P450 family. (463 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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