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DPEP1 DPEP1 AVPR1B AVPR1B ADORA1 ADORA1 DPEP3 DPEP3 CHST12 CHST12 GPC2 GPC2 METAP2 METAP2 CHST14 CHST14 ADORA2A ADORA2A GPC3 GPC3 GPC4 GPC4 ELOVL3 ELOVL3 GPC5 GPC5 LOC101374418 LOC101374418 IL12B IL12B ADORA2B ADORA2B CHST8 CHST8 SDC1 SDC1 LOC101377413 LOC101377413 LOC101382544 LOC101382544 LOC101381770 LOC101381770 AVPR2 AVPR2 PANX2 PANX2 PANX1 PANX1 CHST9 CHST9 ELOVL6 ELOVL6 PTGS1 PTGS1 CGA CGA GPC1 GPC1 OXTR OXTR PANX3 PANX3 CHST11 CHST11 SDC2 SDC2 LOC101375248 LOC101375248 FUT2 FUT2 FUT1 FUT1 ACE2 ACE2 AVPR1A AVPR1A NPSR1 NPSR1 CHST13 CHST13 CHST10 CHST10 LOC101375937 LOC101375937 SDC3 SDC3 DPEP2 DPEP2 APOA1 APOA1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DPEP1Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (410 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (420 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
DPEP3Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (474 aa)
CHST12Carbohydrate sulfotransferase. (419 aa)
GPC2Glypican-2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (587 aa)
METAP2Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. (478 aa)
CHST14Carbohydrate sulfotransferase. (376 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (409 aa)
GPC3Glypican-3 isoform X1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
GPC4Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
ELOVL3Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa)
GPC5Glypican-5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (673 aa)
LOC101374418Glypican-6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (336 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa)
CHST8Carbohydrate sulfotransferase. (427 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (307 aa)
LOC101377413Angiotensin-converting enzyme. (1312 aa)
LOC101382544Angiotensin-converting enzyme. (772 aa)
LOC101381770Glypican-6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (219 aa)
AVPR2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (370 aa)
PANX2Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (671 aa)
PANX1Pannexin; Structural component of the gap junctions and the hemichannels. (427 aa)
CHST9Carbohydrate sulfotransferase. (437 aa)
ELOVL6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa)
PTGS1Prostaglandin G/H synthase 1 isoform X1. (632 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
GPC1Glypican-1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (385 aa)
PANX3Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (392 aa)
CHST11Carbohydrate sulfotransferase. (352 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
LOC101375248L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (412 aa)
FUT2L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (340 aa)
FUT1L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (411 aa)
ACE2Angiotensin-converting enzyme. (732 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
NPSR1LOW QUALITY PROTEIN: neuropeptide S receptor. (374 aa)
CHST13Carbohydrate sulfotransferase. (428 aa)
CHST10Carbohydrate sulfotransferase. (391 aa)
LOC101375937Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (324 aa)
SDC3Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (400 aa)
DPEP2Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (471 aa)
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (266 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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