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GALNT12 GALNT12 PPP1CA PPP1CA LFNG LFNG GALNT18 GALNT18 ACVR1 ACVR1 PPP1CB PPP1CB ADCY3 ADCY3 GALNT5 GALNT5 GALNTL6 GALNTL6 GALNT7 GALNT7 PPP1CC PPP1CC PPTC7 PPTC7 DIS3L2 DIS3L2 GALNT3 GALNT3 BMPR1B BMPR1B ARG2 ARG2 GALNT16 GALNT16 ACVR2A ACVR2A GALNT1 GALNT1 RFNG RFNG GALNT2 GALNT2 RPE RPE AMHR2 AMHR2 GART GART WBSCR17 WBSCR17 GALNT11 GALNT11 GALNT15 GALNT15 CLP1 CLP1 GALNT14 GALNT14 FAN1 FAN1 GALNT10 GALNT10 MFNG MFNG ACVR2B ACVR2B RTCB RTCB B3GAT1 B3GAT1 GALNT4 GALNT4 ADCY2 ADCY2 CNDP1 CNDP1 CNDP2 CNDP2 TGFBR2 TGFBR2 GALNT9 GALNT9 GALNT8 GALNT8 B3GAT2 B3GAT2 GALNT13 GALNT13 ADCY5 ADCY5 XPNPEP3 XPNPEP3 PPEF1 PPEF1 ADCY6 ADCY6 ADCY4 ADCY4 PEPD PEPD IDH1 IDH1 ADCY7 ADCY7 ADCY1 ADCY1 MRE11A MRE11A B3GAT3 B3GAT3 ITPA ITPA IDH2 IDH2 GALNT6 GALNT6 ACVRL1 ACVRL1 ARG1 ARG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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GALNT12Polypeptide N-acetylgalactosaminyltransferase. (579 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase. (381 aa)
GALNT18Polypeptide N-acetylgalactosaminyltransferase. (607 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
GALNT5Polypeptide N-acetylgalactosaminyltransferase. (936 aa)
GALNTL6Polypeptide N-acetylgalactosaminyltransferase. (601 aa)
GALNT7Polypeptide N-acetylgalactosaminyltransferase. (657 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
PPTC7Protein phosphatase; Belongs to the PP2C family. (304 aa)
DIS3L2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (880 aa)
GALNT3Polypeptide N-acetylgalactosaminyltransferase. (632 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ARG2Arginase. (354 aa)
GALNT16Polypeptide N-acetylgalactosaminyltransferase. (557 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
GALNT1Polypeptide N-acetylgalactosaminyltransferase. (559 aa)
RFNGBeta-1,3-N-acetylglucosaminyltransferase. (348 aa)
GALNT2Polypeptide N-acetylgalactosaminyltransferase. (571 aa)
RPERibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
AMHR2Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (549 aa)
GARTTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa)
WBSCR17Polypeptide N-acetylgalactosaminyltransferase. (598 aa)
GALNT11Polypeptide N-acetylgalactosaminyltransferase. (610 aa)
GALNT15Polypeptide N-acetylgalactosaminyltransferase. (634 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)
GALNT14Polypeptide N-acetylgalactosaminyltransferase. (557 aa)
FAN1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1023 aa)
GALNT10Polypeptide N-acetylgalactosaminyltransferase. (603 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (321 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
RTCBRNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. (505 aa)
B3GAT1Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (369 aa)
GALNT4Polypeptide N-acetylgalactosaminyltransferase. (582 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
CNDP1beta-Ala-His dipeptidase. (485 aa)
CNDP2Cytosolic non-specific dipeptidase isoform X1. (473 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
GALNT9Polypeptide N-acetylgalactosaminyltransferase. (604 aa)
GALNT8Polypeptide N-acetylgalactosaminyltransferase. (633 aa)
B3GAT2Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (289 aa)
GALNT13Polypeptide N-acetylgalactosaminyltransferase. (561 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
XPNPEP3Probable Xaa-Pro aminopeptidase 3. (507 aa)
PPEF1Serine/threonine-protein phosphatase with EF-hands. (661 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
PEPDxaa-Pro dipeptidase. (498 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ADCY1Adenylate cyclase type 1. (907 aa)
MRE11ADouble-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (708 aa)
B3GAT3Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (342 aa)
ITPAInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. (361 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (451 aa)
GALNT6Polypeptide N-acetylgalactosaminyltransferase. (622 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (523 aa)
ARG1Arginase. (330 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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