STRINGSTRING
PIK3R2 PIK3R2 FGF19 FGF19 PIK3R4 PIK3R4 PDE3B PDE3B LOC101370160 LOC101370160 LOC101374328 LOC101374328 FGFR2 FGFR2 FGF2 FGF2 FGFR4 FGFR4 FGF7 FGF7 PIK3R1 PIK3R1 FGF23 FGF23 FGF6 FGF6 KL KL FGF10 FGF10 PIK3C3 PIK3C3 FGF16 FGF16 FLT3 FLT3 PIK3CB PIK3CB PTPN11 PTPN11 FLT3LG FLT3LG IRS1 IRS1 IRS2 IRS2 FGF20 FGF20 FGF5 FGF5 GAB1 GAB1 FRS2 FRS2 THEM4 THEM4 PDPK1 PDPK1 FGF17 FGF17 FGF8 FGF8 FGF9 FGF9 LOC101378833 LOC101378833 LOC101369007 LOC101369007 SPEM1 SPEM1 PIK3CA PIK3CA FGF1 FGF1 FGFR3 FGFR3 KLB KLB FGF22 FGF22 FGFR1 FGFR1 GRB2 GRB2 FGF3 FGF3 FGF4 FGF4 TRIB3 TRIB3 FGF18 FGF18 GAB2 GAB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
PIK3R4Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa)
PDE3BPhosphodiesterase. (1112 aa)
LOC101370160Toll-like receptor 9 isoform X1. (1056 aa)
LOC101374328Tyrosine-protein phosphatase non-receptor type 11-like. (581 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (377 aa)
FGFR4Fibroblast growth factor receptor. (856 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (245 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
KLKlotho. (1010 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
FLT3LGFms-related tyrosine kinase 3 ligand. (294 aa)
IRS1Insulin receptor substrate 1. (1233 aa)
IRS2Insulin receptor substrate 2. (1327 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (270 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (724 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
THEM4Acyl-coenzyme A thioesterase THEM4. (259 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC101378833Insulin receptor substrate 2-like. (528 aa)
LOC101369007Uncharacterized protein C17orf74 homolog. (480 aa)
SPEM1Spermatid maturation protein 1. (311 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FGFR3Fibroblast growth factor receptor. (808 aa)
KLBBeta-klotho. (1037 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
FGFR1Fibroblast growth factor receptor. (820 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
TRIB3Tribbles homolog 3. (358 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
GAB2GRB2-associated-binding protein 2. (677 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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