STRINGSTRING
HRAS HRAS GAB1 GAB1 NRG3 NRG3 SOS1 SOS1 SRMS SRMS PTK6 PTK6 FNDC3B FNDC3B LOC101376426 LOC101376426 EGFR EGFR BTC BTC SRC SRC EREG EREG UBA52 UBA52 YES1 YES1 USP8 USP8 ERAS ERAS DIAPH1 DIAPH1 HBEGF HBEGF NRG2 NRG2 PIK3CA PIK3CA CDC37 CDC37 FNDC3A FNDC3A AKT3 AKT3 CUL5 CUL5 PTPN18 PTPN18 RNF41 RNF41 ERBB3 ERBB3 STUB1 STUB1 PRKCE PRKCE RPS27A RPS27A SHC1 SHC1 ERBB2IP ERBB2IP CSDE1 CSDE1 NRAS NRAS LOC101371484 LOC101371484 MATK MATK LOC101371369 LOC101371369 PIK3R1 PIK3R1 LOC101386062 LOC101386062 PRKCA PRKCA LOC101367134 LOC101367134 NRG1 NRG1 LOC101378783 LOC101378783 MEMO1 MEMO1 FYN FYN NRG4 NRG4 PTPN12 PTPN12 KRAS KRAS EGF EGF AKT2 AKT2 UBC UBC AKT1 AKT1 ERBB2 ERBB2 GRB7 GRB7 GRB2 GRB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HRASGTPase HRas isoform X1. (189 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (724 aa)
NRG3Pro-neuregulin-3, membrane-bound isoform isoform X1. (722 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1333 aa)
SRMSTyrosine-protein kinase. (493 aa)
PTK6Tyrosine-protein kinase. (451 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1208 aa)
LOC101376426Ubiquitin-like. (101 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
BTCProbetacellulin. (178 aa)
SRCTyrosine-protein kinase. (553 aa)
EREGProepiregulin isoform X1. (166 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X1. (183 aa)
YES1Tyrosine-protein kinase. (541 aa)
USP8Ubiquitin carboxyl-terminal hydrolase 8 isoform X1; Belongs to the peptidase C19 family. (1116 aa)
ERASGTPase ERas. (233 aa)
DIAPH1Protein diaphanous homolog 1 isoform X1. (1284 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
NRG2Pro-neuregulin-2, membrane-bound isoform isoform X1. (847 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CDC37Hsp90 co-chaperone Cdc37. (380 aa)
FNDC3AFibronectin type-III domain-containing protein 3A isoform X1. (1199 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
CUL5Cullin-5; Belongs to the cullin family. (780 aa)
PTPN18Tyrosine-protein phosphatase non-receptor type 18 isoform X1. (452 aa)
RNF41E3 ubiquitin-protein ligase NRDP1. (317 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1339 aa)
STUB1E3 ubiquitin-protein ligase CHIP. (303 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
ERBB2IPProtein LAP2 isoform X7. (1460 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (852 aa)
NRASGTPase NRas. (189 aa)
LOC101371484Receptor tyrosine-protein kinase erbB-4. (838 aa)
MATKTyrosine-protein kinase. (496 aa)
LOC101371369Polyubiquitin. (153 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
LOC101386062Ubiquitin-like. (109 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
LOC101367134GTPase HRas-like. (177 aa)
NRG1Pro-neuregulin-1, membrane-bound isoform isoform X1. (855 aa)
LOC101378783Fibronectin type III domain containing protein 3C1-like. (1383 aa)
MEMO1Protein MEMO1 isoform X1. (297 aa)
FYNTyrosine-protein kinase. (537 aa)
NRG4Pro-neuregulin-4, membrane-bound isoform. (131 aa)
PTPN12Tyrosine-protein phosphatase non-receptor type 12 isoform X1. (783 aa)
KRASGTPase KRas isoform X1. (227 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1210 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
UBCpolyubiquitin-C. (229 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ERBB2Receptor protein-tyrosine kinase. (1281 aa)
GRB7Growth factor receptor-bound protein 7 isoform X1. (530 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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