50 items (Odobenus rosmarus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GRB10	Growth factor receptor-bound protein 10. (586 aa)
	KITLG	Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	CBL	E3 ubiquitin-protein ligase CBL. (910 aa)
	LOC101378783	Fibronectin type III domain containing protein 3C1-like. (1383 aa)
	YES1	Tyrosine-protein kinase. (541 aa)
	STAT3	Signal transducer and activator of transcription. (770 aa)
	STAT5A	Signal transducer and activator of transcription. (794 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
	PTK6	Tyrosine-protein kinase. (451 aa)
	SRMS	Tyrosine-protein kinase. (493 aa)
	SOS1	Son of sevenless homolog 1 isoform X1. (1333 aa)
	JAK2	Tyrosine-protein kinase. (1130 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	MMP9	Matrix metalloproteinase-9. (704 aa)
	LOC101380319	LOW QUALITY PROTEIN: GRB2-related adapter protein. (306 aa)
	PIK3R2	Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	LOC101371794	Chymase isoform X1; Belongs to the peptidase S1 family. (247 aa)
	ELSPBP1	Epididymal sperm-binding protein 1. (223 aa)
	PIK3R3	Phosphatidylinositol 3-kinase regulatory subunit gamma. (507 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A isoform X1. (1199 aa)
	FES	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (820 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	GRAP2	GRB2-related adapter protein 2. (316 aa)
	ERAS	GTPase ERas. (233 aa)
	GAB2	GRB2-associated-binding protein 2. (677 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B. (1208 aa)
	FER	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (823 aa)
	GRB2	Growth factor receptor-bound protein 2 isoform X1. (217 aa)
	GRB7	Growth factor receptor-bound protein 7 isoform X1. (530 aa)
	SH2B3	SH2B adapter protein 3. (578 aa)
	TEC	Tyrosine-protein kinase. (631 aa)
	LOC101372053	Tyrosine-protein kinase. (620 aa)
	KRAS	GTPase KRas isoform X1. (227 aa)
	STAT5B	Signal transducer and activator of transcription. (818 aa)
	SRC	Tyrosine-protein kinase. (553 aa)
	LOC101374328	Tyrosine-protein phosphatase non-receptor type 11-like. (581 aa)
	STAT1	Signal transducer and activator of transcription. (750 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (852 aa)
	NRAS	GTPase NRas. (189 aa)
	SH2B2	LOW QUALITY PROTEIN: SH2B adapter protein 2. (813 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (982 aa)
	VAV1	Proto-oncogene vav isoform X1. (864 aa)
	PTPRU	Receptor-type tyrosine-protein phosphatase U isoform X1. (1452 aa)
	CHEK1	Serine/threonine-protein kinase Chk1 isoform X1; Belongs to the protein kinase superfamily. (476 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
	LOC101367134	GTPase HRas-like. (177 aa)

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBL	FYN	A0A2U3WTE6	A0A2U3WDX9	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.816
CBL	GRAP2	A0A2U3WTE6	A0A2U3VQM9	E3 ubiquitin-protein ligase CBL.	GRB2-related adapter protein 2.	0.744
CBL	GRB2	A0A2U3WTE6	A0A2U3VHU3	E3 ubiquitin-protein ligase CBL.	Growth factor receptor-bound protein 2 isoform X1.	0.998
CBL	JAK2	A0A2U3WTE6	A0A2U3WH50	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.582
CBL	KIT	A0A2U3WTE6	A0A2U3ZCP5	E3 ubiquitin-protein ligase CBL.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.732
CBL	KITLG	A0A2U3WTE6	A0A2U3WZ03	E3 ubiquitin-protein ligase CBL.	Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.	0.494
CBL	LOC101374328	A0A2U3WTE6	A0A2U3ZMT2	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein phosphatase non-receptor type 11-like.	0.623
CBL	LOC101380319	A0A2U3WTE6	A0A2U3WA73	E3 ubiquitin-protein ligase CBL.	LOW QUALITY PROTEIN: GRB2-related adapter protein.	0.803
CBL	LYN	A0A2U3WTE6	A0A2U3WXZ8	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.927
CBL	PIK3CA	A0A2U3WTE6	A0A2U3VSW6	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.864
CBL	PIK3R1	A0A2U3WTE6	A0A2U3X1Z3	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.988
CBL	PIK3R2	A0A2U3WTE6	A0A2U3W8T2	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.921
CBL	PIK3R3	A0A2U3WTE6	A0A2U3VYN3	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 3-kinase regulatory subunit gamma.	0.894
CBL	PTK6	A0A2U3WTE6	A0A2U3WMI5	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.816
CBL	PTPN11	A0A2U3WTE6	A0A2U3WN02	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.700
CBL	PTPN6	A0A2U3WTE6	A0A2U3WWR1	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.469
CBL	SH2B2	A0A2U3WTE6	A0A2U3ZEC4	E3 ubiquitin-protein ligase CBL.	LOW QUALITY PROTEIN: SH2B adapter protein 2.	0.970
CBL	SH2B3	A0A2U3WTE6	A0A2U3VLM6	E3 ubiquitin-protein ligase CBL.	SH2B adapter protein 3.	0.611
CBL	SOS1	A0A2U3WTE6	A0A2U3WM57	E3 ubiquitin-protein ligase CBL.	Son of sevenless homolog 1 isoform X1.	0.592
CBL	SRC	A0A2U3WTE6	A0A2U3ZNJ0	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.885