STRINGSTRING
PSEN2 PSEN2 RELA RELA PSENEN PSENEN PSEN1 PSEN1 NFKB1 NFKB1 ADAM17 ADAM17 APH1A APH1A NCSTN NCSTN TRAF6 TRAF6 APH1B APH1B CCDC71L CCDC71L NGFR NGFR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (464 aa)
RELATranscription factor p65. (539 aa)
PSENENGamma-secretase subunit PEN-2. (101 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa)
ADAM17Disintegrin and metalloproteinase domain-containing protein 17. (822 aa)
APH1AGamma-secretase subunit APH-1A isoform X1. (265 aa)
NCSTNNicastrin isoform X1. (708 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
APH1BGamma-secretase subunit APH-1B isoform X1. (257 aa)
CCDC71LCoiled-coil domain-containing protein 71L. (230 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (421 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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