STRINGSTRING
LOC101384041 LOC101384041 NUP98 NUP98 RNF169 RNF169 SENP5 SENP5 NPM1 NPM1 TOPORS TOPORS NUP35 NUP35 NUP214 NUP214 NUP188 NUP188 SEC13 SEC13 PHC3 PHC3 SUMO1 SUMO1 SATB2 SATB2 UHRF2 UHRF2 PARP1 PARP1 LOC101381898 LOC101381898 RELA RELA TIGD3 TIGD3 SUMO2 SUMO2 KCTD2 KCTD2 LOC101372925 LOC101372925 PCGF2 PCGF2 TOP2A TOP2A THRA THRA PIAS4 PIAS4 MTA1 MTA1 NUP210 NUP210 SENP1 SENP1 CTBP1 CTBP1 CTXN2 CTXN2 TFE3 TFE3 ZNF618 ZNF618 NSMCE1 NSMCE1 NFATC2IP NFATC2IP SMC5 SMC5 LOC101374670 LOC101374670 JRKL JRKL LOC101374392 LOC101374392 CENPB CENPB BLM BLM RANBP2 RANBP2 PIAS3 PIAS3 NUP88 NUP88 LOC101367539 LOC101367539 NUP160 NUP160 NR1H3 NR1H3 HIC2 HIC2 TIGD5 TIGD5 RECQL4 RECQL4 SAE1 SAE1 SCML2 SCML2 TIGD4 TIGD4 CDCA8 CDCA8 PPARGC1A PPARGC1A TIGD6 TIGD6 LOC101370219 LOC101370219 NUP210L NUP210L UBE2I UBE2I MEIOB MEIOB CETN3 CETN3 ZMIZ1 ZMIZ1 FOXD1 FOXD1 RANBP3L RANBP3L NUP155 NUP155 NSMCE4A NSMCE4A HIC1 HIC1 POGZ POGZ CASP8AP2 CASP8AP2 CBX4 CBX4 CBX2 CBX2 NUP133 NUP133 LOC101363339 LOC101363339 NCOA5 NCOA5 LOC101366111 LOC101366111 TPR TPR RNF2 RNF2 LOC101373164 LOC101373164 LOC101383883 LOC101383883 NUP107 NUP107 NUP153 NUP153 AAAS AAAS NUP205 NUP205 SCMH1 SCMH1 LOC101377981 LOC101377981 SENP2 SENP2 LOC101372008 LOC101372008 LOC101382175 LOC101382175 SMC6 SMC6 SP5 SP5 RING1 RING1 LOC101370984 LOC101370984 PML PML RWDD2A RWDD2A SEH1L SEH1L PIAS2 PIAS2 SP3 SP3 MDC1 MDC1 RWDD3 RWDD3 FAM111A FAM111A FAM111B FAM111B NUPL1 NUPL1 ZBED4 ZBED4 NDNL2 NDNL2 NR1H2 NR1H2 INCENP INCENP NSMCE2 NSMCE2 HDAC4 HDAC4 MBD1 MBD1 CFAP53 CFAP53 LOC101368752 LOC101368752 SUMO3 SUMO3 DDX17 DDX17 LOC101363366 LOC101363366 TOP1 TOP1 LOC101375127 LOC101375127 FOXD2 FOXD2 NUP37 NUP37 LOC101368292 LOC101368292 FOXD3 FOXD3 FOXL2 FOXL2 UBA2 UBA2 ZMIZ2 ZMIZ2 EID3 EID3 TDG TDG VTCN1 VTCN1 LOC101363303 LOC101363303 NUP50 NUP50 SCML1 SCML1 ZNF131 ZNF131 LOC101368410 LOC101368410 LOC101384496 LOC101384496 SATB1 SATB1 AR AR LOC101371279 LOC101371279 POGK POGK NUP85 NUP85 RWDD2B RWDD2B SAFB2 SAFB2 RANBP3 RANBP3 NUP93 NUP93 LOC101383066 LOC101383066 LOC101383358 LOC101383358 SP110 SP110 SAFB SAFB ZBTB38 ZBTB38 TOP2B TOP2B SP4 SP4 CENPBD1 CENPBD1 AURKB AURKB LOC101379117 LOC101379117 ZBED1 ZBED1 E4F1 E4F1 TIGD7 TIGD7 TIGD2 TIGD2 NUP43 NUP43 RPA1 RPA1 CBX8 CBX8 MITF MITF NR1I2 NR1I2 LOC105757712 LOC105757712 NUP54 NUP54 PHC2 PHC2 JRK JRK BMI1 BMI1 LOC101380414 LOC101380414 TFEB TFEB MKL2 MKL2 DNMT3B DNMT3B AURKC AURKC PHC1 PHC1 LOC105758097 LOC105758097 PIAS1 PIAS1 TRIM7 TRIM7 LOC101369784 LOC101369784 CETN2 CETN2 THRB THRB LOC101383373 LOC101383373 LOC101384780 LOC101384780
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101384041Melanoma-associated antigen B17. (320 aa)
NUP98Nuclear pore complex protein Nup98-Nup96 isoform X1. (1800 aa)
RNF169E3 ubiquitin-protein ligase RNF169. (708 aa)
SENP5Sentrin-specific protease 5 isoform X1. (753 aa)
NPM1Nucleophosmin isoform X1. (294 aa)
TOPORSE3 ubiquitin-protein ligase Topors isoform X1. (1044 aa)
NUP35Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (329 aa)
NUP214Nuclear pore complex protein Nup214. (2084 aa)
NUP188Nucleoporin NUP188 homolog. (1751 aa)
SEC13Protein SEC13 homolog isoform X1; Belongs to the WD repeat SEC13 family. (322 aa)
PHC3Polyhomeotic-like protein 3 isoform X1. (995 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
SATB2DNA-binding protein SATB. (733 aa)
UHRF2E3 ubiquitin-protein ligase UHRF2. (803 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
LOC101381898Small ubiquitin-related modifier 2-like. (98 aa)
RELATranscription factor p65. (539 aa)
TIGD3Tigger transposable element-derived protein 3. (476 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
KCTD2BTB/POZ domain-containing protein KCTD2. (263 aa)
LOC101372925Uncharacterized protein LOC101372925. (256 aa)
PCGF2Polycomb group RING finger protein 2. (344 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1534 aa)
THRAThyroid hormone receptor alpha. (410 aa)
PIAS4E3 SUMO-protein ligase PIAS4. (509 aa)
MTA1Metastasis-associated protein MTA1. (816 aa)
NUP210Nuclear pore membrane glycoprotein 210. (1893 aa)
SENP1Sentrin-specific protease 1. (645 aa)
CTBP1C-terminal-binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (429 aa)
CTXN2Cortexin-2. (81 aa)
TFE3Transcription factor E3 isoform X1. (571 aa)
ZNF618Zinc finger protein 618 isoform X1. (954 aa)
NSMCE1Non-structural maintenance of chromosomes element 1 homolog isoform X1. (283 aa)
NFATC2IPNFATC2-interacting protein. (549 aa)
SMC5Structural maintenance of chromosomes protein 5. (1107 aa)
LOC101374670Centrin-2. (172 aa)
JRKLJerky protein homolog-like. (524 aa)
LOC101374392Uncharacterized protein C20orf196 homolog. (206 aa)
CENPBMajor centromere autoantigen B. (493 aa)
BLMBloom syndrome protein isoform X1. (1428 aa)
RANBP2E3 SUMO-protein ligase RanBP2 isoform X1. (3098 aa)
PIAS3E3 SUMO-protein ligase PIAS3. (628 aa)
NUP88Nuclear pore complex protein Nup88. (734 aa)
LOC101367539Nuclear envelope pore membrane protein POM 121C. (1210 aa)
NUP160Nuclear pore complex protein Nup160. (1402 aa)
NR1H3Oxysterols receptor LXR-alpha isoform X1. (447 aa)
HIC2Hypermethylated in cancer 2 protein. (617 aa)
TIGD5Tigger transposable element-derived protein 5. (649 aa)
RECQL4ATP-dependent DNA helicase Q4. (1183 aa)
SAE1SUMO-activating enzyme subunit 1 isoform X1. (346 aa)
SCML2Sex comb on midleg-like protein 2 isoform X1. (698 aa)
TIGD4Tigger transposable element-derived protein 4. (511 aa)
CDCA8Borealin. (280 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (803 aa)
TIGD6Tigger transposable element-derived protein 6. (524 aa)
LOC101370219Small ubiquitin-related modifier. (95 aa)
NUP210LNuclear pore membrane glycoprotein 210-like. (1797 aa)
UBE2ISUMO-conjugating enzyme UBC9 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
MEIOBMeiosis-specific with OB domain-containing protein isoform X2. (471 aa)
CETN3Centrin-3. (167 aa)
ZMIZ1Zinc finger MIZ domain-containing protein 1. (1066 aa)
FOXD1Forkhead box protein D1. (461 aa)
RANBP3LRan-binding protein 3-like isoform X1. (491 aa)
NUP155Nuclear pore complex protein Nup155. (1379 aa)
NSMCE4ANon-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (385 aa)
HIC1Hypermethylated in cancer 1 protein isoform X1. (736 aa)
POGZPogo transposable element with ZNF domain isoform X1. (1414 aa)
CASP8AP2CASP8-associated protein 2. (1964 aa)
CBX4E3 SUMO-protein ligase CBX4. (552 aa)
CBX2Chromobox protein homolog 2. (528 aa)
NUP133Nuclear pore complex protein Nup133. (1156 aa)
LOC101363339Small ubiquitin-related modifier. (101 aa)
NCOA5Nuclear receptor coactivator 5 isoform X1. (579 aa)
LOC101366111Tigger transposable element-derived protein 1-like. (362 aa)
TPRNucleoprotein TPR. (2439 aa)
RNF2E3 ubiquitin-protein ligase RING2 isoform X1. (336 aa)
LOC101373164Small ubiquitin-related modifier. (95 aa)
LOC101383883Small ubiquitin-related modifier. (101 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
NUP153Nuclear pore complex protein Nup153 isoform X1. (1472 aa)
AAASAladin isoform X1. (546 aa)
NUP205Nuclear pore complex protein Nup205. (2012 aa)
SCMH1Polycomb protein SCMH1 isoform X1. (690 aa)
LOC101377981Small ubiquitin-related modifier. (95 aa)
SENP2Sentrin-specific protease 2. (590 aa)
LOC101372008Melanoma-associated antigen F1. (325 aa)
LOC101382175Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
SMC6Structural maintenance of chromosomes protein 6. (1097 aa)
SP5Transcription factor Sp5. (398 aa)
RING1E3 ubiquitin-protein ligase RING1. (406 aa)
LOC101370984Melanoma-associated antigen B3. (356 aa)
PMLProtein PML. (928 aa)
RWDD2ARWD domain-containing protein. (306 aa)
SEH1LNucleoporin SEH1 isoform X1; Belongs to the WD repeat SEC13 family. (421 aa)
PIAS2E3 SUMO-protein ligase PIAS2 isoform X1. (621 aa)
SP3Transcription factor Sp3 isoform X1. (783 aa)
MDC1Mediator of DNA damage checkpoint protein 1. (1959 aa)
RWDD3RWD domain-containing protein 3 isoform X1. (267 aa)
FAM111ALOW QUALITY PROTEIN: protein FAM111A. (602 aa)
FAM111BLOW QUALITY PROTEIN: protein FAM111B. (729 aa)
NUPL1Nucleoporin p58/p45 isoform X1. (599 aa)
ZBED4Zinc finger BED domain-containing protein 4. (1170 aa)
NDNL2Melanoma-associated antigen G1. (284 aa)
NR1H2Oxysterols receptor LXR-beta. (456 aa)
INCENPInner centromere protein. (858 aa)
NSMCE2E3 SUMO-protein ligase NSE2. (247 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1056 aa)
MBD1methyl-CpG-binding domain protein 1 isoform X1. (658 aa)
CFAP53Cilia- and flagella-associated protein 53. (514 aa)
LOC101368752Melanoma-associated antigen E2. (523 aa)
SUMO3Small ubiquitin-related modifier. (111 aa)
DDX17Probable ATP-dependent RNA helicase DDX17 isoform X1; Belongs to the DEAD box helicase family. (652 aa)
LOC101363366Small ubiquitin-related modifier. (95 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (769 aa)
LOC101375127Nuclear envelope pore membrane protein POM 121-like. (410 aa)
FOXD2Forkhead box protein D2. (495 aa)
NUP37Nucleoporin Nup37 isoform X1. (326 aa)
LOC101368292Tigger transposable element-derived protein 1-like. (593 aa)
FOXD3Forkhead box protein D3. (481 aa)
FOXL2Forkhead box protein L2. (378 aa)
UBA2SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (653 aa)
ZMIZ2Zinc finger MIZ domain-containing protein 2 isoform X1. (922 aa)
EID3Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (370 aa)
TDGG/T mismatch-specific thymine DNA glycosylase. (406 aa)
VTCN1V-set domain-containing T-cell activation inhibitor 1 isoform X1. (282 aa)
LOC101363303Melanoma-associated antigen B17-like. (344 aa)
NUP50Nuclear pore complex protein Nup50. (461 aa)
SCML1Sex comb on midleg-like protein 1. (418 aa)
ZNF131Zinc finger protein 131. (587 aa)
LOC101368410Melanoma-associated antigen B18-like. (338 aa)
LOC101384496Melanoma-associated antigen B10. (348 aa)
SATB1DNA-binding protein SATB. (795 aa)
ARAndrogen receptor. (886 aa)
LOC101371279Melanoma-associated antigen B2-like. (344 aa)
POGKPogo transposable element with KRAB domain. (609 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (514 aa)
RWDD2BRWD domain-containing protein. (290 aa)
SAFB2Scaffold attachment factor B2 isoform X2. (999 aa)
RANBP3Ran-binding protein 3. (586 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (819 aa)
LOC101383066Nuclear body protein SP140. (740 aa)
LOC101383358Nuclear body protein SP140-like protein. (812 aa)
SP110Sp110 nuclear body protein. (714 aa)
SAFBScaffold attachment factor B1 isoform X1. (918 aa)
ZBTB38Zinc finger and BTB domain-containing protein 38. (1194 aa)
TOP2BDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1614 aa)
SP4Transcription factor Sp4. (767 aa)
CENPBD1CENPB DNA-binding domain-containing protein 1. (542 aa)
AURKBAurora kinase B isoform X1; Belongs to the protein kinase superfamily. (354 aa)
LOC101379117Forkhead box protein D4-like 1. (482 aa)
ZBED1Zinc finger BED domain-containing protein 1. (696 aa)
E4F1Transcription factor E4F1 isoform X1. (789 aa)
TIGD7Tigger transposable element-derived protein 7. (548 aa)
TIGD2Tigger transposable element-derived protein 2. (525 aa)
NUP43Nucleoporin Nup43. (380 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
CBX8Chromobox protein homolog 8 isoform X1. (395 aa)
MITFMicrophthalmia-associated transcription factor isoform X1. (526 aa)
NR1I2Nuclear receptor subfamily 1 group I member 2. (482 aa)
LOC105757712CENPB DNA-binding domain-containing protein 1-like. (106 aa)
NUP54Nucleoporin p54 isoform X1. (562 aa)
PHC2Polyhomeotic-like protein 2 isoform X1. (869 aa)
JRKJerky protein homolog. (541 aa)
BMI1Polycomb complex protein BMI-1 isoform X1. (326 aa)
LOC101380414LOW QUALITY PROTEIN: melanoma-associated antigen B1-like. (318 aa)
TFEBTranscription factor EB. (471 aa)
MKL2MKL/myocardin-like protein 2. (1081 aa)
DNMT3BDNA (Cytosine-5)-methyltransferase 3B isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (877 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (307 aa)
PHC1Polyhomeotic-like protein 1. (982 aa)
LOC105758097E3 ubiquitin-protein ligase Topors-like. (730 aa)
PIAS1E3 SUMO-protein ligase PIAS1 isoform X1. (655 aa)
TRIM7Tripartite motif-containing protein 7 isoform X1. (506 aa)
LOC101369784Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (73 aa)
CETN2Centrin-2. (113 aa)
THRBThyroid hormone receptor beta isoform X1. (476 aa)
LOC101383373Melanoma-associated antigen B10-like. (347 aa)
LOC101384780LOW QUALITY PROTEIN: melanoma-associated antigen B10-like. (348 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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