STRINGSTRING
RNF169 RNF169 PHC3 PHC3 SUMO1 SUMO1 PARP1 PARP1 SUMO2 SUMO2 KCTD2 KCTD2 PCGF2 PCGF2 PIAS4 PIAS4 NSMCE1 NSMCE1 NFATC2IP NFATC2IP SMC5 SMC5 LOC101374670 LOC101374670 LOC101374392 LOC101374392 BLM BLM RECQL4 RECQL4 SCML2 SCML2 LOC101370219 LOC101370219 UBE2I UBE2I MEIOB MEIOB CETN3 CETN3 NSMCE4A NSMCE4A CBX4 CBX4 CBX2 CBX2 LOC101363339 LOC101363339 RNF2 RNF2 LOC101373164 LOC101373164 LOC101383883 LOC101383883 SCMH1 SCMH1 LOC101377981 LOC101377981 LOC101372008 LOC101372008 SMC6 SMC6 RING1 RING1 PML PML SEH1L SEH1L MDC1 MDC1 NDNL2 NDNL2 NSMCE2 NSMCE2 LOC101368752 LOC101368752 SUMO3 SUMO3 LOC101363366 LOC101363366 EID3 EID3 TDG TDG LOC101363303 LOC101363303 SCML1 SCML1 LOC101368410 LOC101368410 LOC101384496 LOC101384496 LOC101371279 LOC101371279 LOC101383066 LOC101383066 LOC101383358 LOC101383358 SP110 SP110 RPA1 RPA1 CBX8 CBX8 PHC2 PHC2 BMI1 BMI1 LOC101380414 LOC101380414 PHC1 PHC1 PIAS1 PIAS1 CETN2 CETN2 LOC101383373 LOC101383373 LOC101384780 LOC101384780 LOC101384041 LOC101384041 LOC101370984 LOC101370984
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RNF169E3 ubiquitin-protein ligase RNF169. (708 aa)
PHC3Polyhomeotic-like protein 3 isoform X1. (995 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
KCTD2BTB/POZ domain-containing protein KCTD2. (263 aa)
PCGF2Polycomb group RING finger protein 2. (344 aa)
PIAS4E3 SUMO-protein ligase PIAS4. (509 aa)
NSMCE1Non-structural maintenance of chromosomes element 1 homolog isoform X1. (283 aa)
NFATC2IPNFATC2-interacting protein. (549 aa)
SMC5Structural maintenance of chromosomes protein 5. (1107 aa)
LOC101374670Centrin-2. (172 aa)
LOC101374392Uncharacterized protein C20orf196 homolog. (206 aa)
BLMBloom syndrome protein isoform X1. (1428 aa)
RECQL4ATP-dependent DNA helicase Q4. (1183 aa)
SCML2Sex comb on midleg-like protein 2 isoform X1. (698 aa)
LOC101370219Small ubiquitin-related modifier. (95 aa)
UBE2ISUMO-conjugating enzyme UBC9 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
MEIOBMeiosis-specific with OB domain-containing protein isoform X2. (471 aa)
CETN3Centrin-3. (167 aa)
NSMCE4ANon-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (385 aa)
CBX4E3 SUMO-protein ligase CBX4. (552 aa)
CBX2Chromobox protein homolog 2. (528 aa)
LOC101363339Small ubiquitin-related modifier. (101 aa)
RNF2E3 ubiquitin-protein ligase RING2 isoform X1. (336 aa)
LOC101373164Small ubiquitin-related modifier. (95 aa)
LOC101383883Small ubiquitin-related modifier. (101 aa)
SCMH1Polycomb protein SCMH1 isoform X1. (690 aa)
LOC101377981Small ubiquitin-related modifier. (95 aa)
LOC101372008Melanoma-associated antigen F1. (325 aa)
SMC6Structural maintenance of chromosomes protein 6. (1097 aa)
RING1E3 ubiquitin-protein ligase RING1. (406 aa)
PMLProtein PML. (928 aa)
SEH1LNucleoporin SEH1 isoform X1; Belongs to the WD repeat SEC13 family. (421 aa)
MDC1Mediator of DNA damage checkpoint protein 1. (1959 aa)
NDNL2Melanoma-associated antigen G1. (284 aa)
NSMCE2E3 SUMO-protein ligase NSE2. (247 aa)
LOC101368752Melanoma-associated antigen E2. (523 aa)
SUMO3Small ubiquitin-related modifier. (111 aa)
LOC101363366Small ubiquitin-related modifier. (95 aa)
EID3Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (370 aa)
TDGG/T mismatch-specific thymine DNA glycosylase. (406 aa)
LOC101363303Melanoma-associated antigen B17-like. (344 aa)
SCML1Sex comb on midleg-like protein 1. (418 aa)
LOC101368410Melanoma-associated antigen B18-like. (338 aa)
LOC101384496Melanoma-associated antigen B10. (348 aa)
LOC101371279Melanoma-associated antigen B2-like. (344 aa)
LOC101383066Nuclear body protein SP140. (740 aa)
LOC101383358Nuclear body protein SP140-like protein. (812 aa)
SP110Sp110 nuclear body protein. (714 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
CBX8Chromobox protein homolog 8 isoform X1. (395 aa)
PHC2Polyhomeotic-like protein 2 isoform X1. (869 aa)
BMI1Polycomb complex protein BMI-1 isoform X1. (326 aa)
LOC101380414LOW QUALITY PROTEIN: melanoma-associated antigen B1-like. (318 aa)
PHC1Polyhomeotic-like protein 1. (982 aa)
PIAS1E3 SUMO-protein ligase PIAS1 isoform X1. (655 aa)
CETN2Centrin-2. (113 aa)
LOC101383373Melanoma-associated antigen B10-like. (347 aa)
LOC101384780LOW QUALITY PROTEIN: melanoma-associated antigen B10-like. (348 aa)
LOC101384041Melanoma-associated antigen B17. (320 aa)
LOC101370984Melanoma-associated antigen B3. (356 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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