STRINGSTRING
LOC101369994 LOC101369994 GPHA2 GPHA2 PDE3A PDE3A CALCB CALCB PDE3B PDE3B ADCYAP1R1 ADCYAP1R1 CRHR2 CRHR2 SHC1 SHC1 LOC105757534 LOC105757534 LOC101375171 LOC101375171 GIPR GIPR PDE4A PDE4A GNG11 GNG11 TAAR5 TAAR5 TAAR9 TAAR9 GPBAR1 GPBAR1 LOC101373155 LOC101373155 LOC101373442 LOC101373442 MC3R MC3R NPSR1 NPSR1 IAPP IAPP LOC101384881 LOC101384881 PTGDR PTGDR DRD5 DRD5 PTGER2 PTGER2 LOC101369097 LOC101369097 LOC101368405 LOC101368405 MC2R MC2R GNGT1 GNGT1 GPER1 GPER1 RXFP1 RXFP1 ADRB3 ADRB3 ADM ADM PTH PTH POMC POMC GNGT2 GNGT2 GIP GIP GNG7 GNG7 GNB5 GNB5 ARR3 ARR3 GNG10 GNG10 HTR6 HTR6 MC4R MC4R AVP AVP PDE8A PDE8A GNB4 GNB4 ARRB2 ARRB2 GLP2R GLP2R PRKACA PRKACA RLN3 RLN3 LOC101368814 LOC101368814 GNB2 GNB2 PTH1R PTH1R PRKAR2A PRKAR2A LOC101379027 LOC101379027 GPR176 GPR176 THAP7 THAP7 ADORA2A ADORA2A PTGIR PTGIR GNG8 GNG8 LOC101385288 LOC101385288 FN1 FN1 TAAR1 TAAR1 LOC101384995 LOC101384995 TSHB TSHB HRH2 HRH2 GRK6 GRK6 PDE10A PDE10A ITGB1 ITGB1 CRH CRH PDE7A PDE7A HTR4 HTR4 ADRB2 ADRB2 GNG13 GNG13 LHCGR LHCGR FSHR FSHR PDE11A PDE11A GRK5 GRK5 GCGR GCGR GPR27 GPR27 INSL3 INSL3 PDE4C PDE4C SCTR SCTR ADORA2B ADORA2B FAM83G FAM83G PTHLH PTHLH PTH2R PTH2R GPR20 GPR20 PRKAR1A PRKAR1A GPR84 GPR84 ITGA5 ITGA5 PDE1B PDE1B THAP6 THAP6 RXFP2 RXFP2 GPR173 GPR173 GPR63 GPR63 GNB1 GNB1 GNG2 GNG2 MC5R MC5R PDE4D PDE4D PTGER4 PTGER4 AVPR2 AVPR2 GPR52 GPR52 GPHB5 GPHB5 RAMP3 RAMP3 ADM2 ADM2 PTH2 PTH2 FAP FAP GCG GCG PDE7B PDE7B RAMP1 RAMP1 RAMP2 RAMP2 HTR7 HTR7 CRHR1 CRHR1 PDE8B PDE8B ADCYAP1 ADCYAP1 GPR39 GPR39 GLP1R GLP1R CGA CGA PRKAR2B PRKAR2B GPR83 GPR83 ADRBK2 ADRBK2 GPR45 GPR45 ADRB1 ADRB1 VIP VIP LOC101369871 LOC101369871 GPR85 GPR85 PRKACB PRKACB GNG5 GNG5 GNG3 GNG3 GNG4 GNG4 GHRHR GHRHR GNB3 GNB3 VIPR1 VIPR1 PRKAR1B PRKAR1B VIPR2 VIPR2 DRD1 DRD1 TSHR TSHR GNG12 GNG12 GPR15 GPR15 THAP9 THAP9 ARRB1 ARRB1 PDE2A PDE2A PDE1A PDE1A CALCRL CALCRL GPR21 GPR21 GPR25 GPR25 CNBD2 CNBD2 GHRH GHRH ADRBK1 ADRBK1 CALCR CALCR
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LOC101369994Lutropin subunit beta. (141 aa)
GPHA2Glycoprotein hormone alpha-2. (127 aa)
PDE3APhosphodiesterase. (791 aa)
CALCBCalcitonin gene-related peptide 2 isoform X1. (131 aa)
PDE3BPhosphodiesterase. (1112 aa)
ADCYAP1R1Pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (497 aa)
CRHR2Corticotropin-releasing factor receptor 2 isoform X1; Belongs to the G-protein coupled receptor 2 family. (437 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
LOC105757534Phosphodiesterase. (427 aa)
LOC101375171LOW QUALITY PROTEIN: trace amine-associated receptor 3-like. (343 aa)
GIPRGastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
PDE4APhosphodiesterase. (871 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
TAAR5LOW QUALITY PROTEIN: trace amine-associated receptor 5; Belongs to the G-protein coupled receptor 1 family. (338 aa)
TAAR9LOW QUALITY PROTEIN: trace amine-associated receptor 9; Belongs to the G-protein coupled receptor 1 family. (259 aa)
GPBAR1LOW QUALITY PROTEIN: G-protein coupled bile acid receptor 1. (356 aa)
LOC101373155LOW QUALITY PROTEIN: trace amine-associated receptor 8; Belongs to the G-protein coupled receptor 1 family. (339 aa)
LOC101373442LOW QUALITY PROTEIN: trace amine-associated receptor 6; Belongs to the G-protein coupled receptor 1 family. (340 aa)
MC3RMelanocortin receptor 3. (322 aa)
NPSR1LOW QUALITY PROTEIN: neuropeptide S receptor. (374 aa)
IAPPIslet amyloid polypeptide. (89 aa)
LOC1013848815-hydroxytryptamine receptor 7. (235 aa)
PTGDRProstaglandin D2 receptor. (358 aa)
DRD5D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (474 aa)
PTGER2Prostaglandin E2 receptor EP2 subtype; Belongs to the G-protein coupled receptor 1 family. (353 aa)
LOC101369097Calcitonin receptor-stimulating peptide 1. (126 aa)
LOC101368405Calcitonin-like isoform X1. (147 aa)
MC2RAdrenocorticotropic hormone receptor. (297 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (94 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
RXFP1Relaxin receptor 1 isoform X1. (738 aa)
ADRB3Beta-3 adrenergic receptor. (408 aa)
ADMADM. (188 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
POMCPro-opiomelanocortin. (258 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
GIPGastric inhibitory polypeptide. (145 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5 isoform X1. (395 aa)
ARR3arrestin-C. (392 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
HTR65-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (440 aa)
MC4RMelanocortin receptor 4. (332 aa)
AVPVasopressin-neurophysin 2-copeptin; Belongs to the vasopressin/oxytocin family. (166 aa)
PDE8APhosphodiesterase. (835 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
ARRB2Beta-arrestin-2 isoform X1. (420 aa)
GLP2RGlucagon-like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family. (529 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
RLN3Relaxin-3. (139 aa)
LOC101368814Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X1. (340 aa)
PTH1RParathyroid hormone/parathyroid hormone-related peptide receptor; Belongs to the G-protein coupled receptor 2 family. (586 aa)
PRKAR2AcAMP-dependent protein kinase type II-alpha regulatory subunit isoform X1. (401 aa)
LOC101379027Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GPR176Probable G-protein coupled receptor 176. (515 aa)
THAP7THAP domain-containing protein 7. (313 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (409 aa)
PTGIRProstacyclin receptor; Belongs to the G-protein coupled receptor 1 family. (408 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC101385288LOW QUALITY PROTEIN: trace amine-associated receptor 2; Belongs to the G-protein coupled receptor 1 family. (331 aa)
FN1Fibronectin isoform X1. (2476 aa)
TAAR1Trace amine-associated receptor 1; Belongs to the G-protein coupled receptor 1 family. (338 aa)
LOC101384995Trace amine-associated receptor 4; Belongs to the G-protein coupled receptor 1 family. (347 aa)
TSHBThyrotropin subunit beta. (158 aa)
HRH2Histamine H2 receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (595 aa)
PDE10APhosphodiesterase. (794 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
CRHCorticoliberin. (196 aa)
PDE7APhosphodiesterase. (483 aa)
HTR45-hydroxytryptamine receptor 4 isoform X1; Belongs to the G-protein coupled receptor 1 family. (388 aa)
ADRB2Beta-2 adrenergic receptor. (418 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (695 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (692 aa)
PDE11APhosphodiesterase. (934 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)
GCGRLOW QUALITY PROTEIN: glucagon receptor; Belongs to the G-protein coupled receptor 2 family. (864 aa)
GPR27Probable G-protein coupled receptor 27. (376 aa)
INSL3Insulin-like 3. (145 aa)
PDE4CPhosphodiesterase. (694 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (449 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa)
FAM83GProtein FAM83G. (822 aa)
PTHLHParathyroid hormone-related protein. (177 aa)
PTH2RParathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. (550 aa)
GPR20G-protein coupled receptor 20; Belongs to the G-protein coupled receptor 1 family. (357 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (381 aa)
GPR84G-protein coupled receptor 84. (393 aa)
ITGA5Integrin alpha-5; Belongs to the integrin alpha chain family. (1104 aa)
PDE1BPhosphodiesterase. (496 aa)
THAP6THAP domain-containing protein 6. (222 aa)
RXFP2Relaxin receptor 2 isoform X1. (735 aa)
GPR173Probable G-protein coupled receptor 173. (373 aa)
GPR63Probable G-protein coupled receptor 63. (419 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform X1. (340 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
MC5RMelanocortin receptor 5. (324 aa)
PDE4DPhosphodiesterase. (811 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (489 aa)
AVPR2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (370 aa)
GPR52Probable G-protein coupled receptor 52; Belongs to the G-protein coupled receptor 1 family. (361 aa)
GPHB5Glycoprotein hormone beta-5. (130 aa)
RAMP3Receptor activity-modifying protein 3. (149 aa)
ADM2ADM2. (142 aa)
PTH2Tuberoinfundibular peptide of 39 residues. (100 aa)
FAPProlyl endopeptidase FAP isoform X1; Belongs to the peptidase S9B family. (760 aa)
GCGGlucagon. (180 aa)
PDE7BcAMP-specific 3',5'-cyclic phosphodiesterase 7B; Belongs to the cyclic nucleotide phosphodiesterase family. (339 aa)
RAMP1Receptor activity-modifying protein 1. (148 aa)
RAMP2Receptor activity-modifying protein 2. (176 aa)
HTR75-hydroxytryptamine receptor 7. (182 aa)
CRHR1Corticotropin-releasing factor receptor 1 isoform X1; Belongs to the G-protein coupled receptor 2 family. (415 aa)
PDE8BPhosphodiesterase. (891 aa)
ADCYAP1Pituitary adenylate cyclase-activating polypeptide. (176 aa)
GPR39G-protein coupled receptor 39; Belongs to the G-protein coupled receptor 1 family. (453 aa)
GLP1RGlucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
PRKAR2BcAMP-dependent protein kinase type II-beta regulatory subunit. (417 aa)
GPR83Probable G-protein coupled receptor 83; Belongs to the G-protein coupled receptor 1 family. (422 aa)
ADRBK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)
GPR45Probable G-protein coupled receptor 45. (373 aa)
ADRB1Beta-1 adrenergic receptor. (468 aa)
VIPVIP peptides isoform X1. (170 aa)
LOC101369871Follitropin subunit beta. (129 aa)
GPR85Probable G-protein coupled receptor 85. (370 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GHRHRGrowth hormone-releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
VIPR1Vasoactive intestinal polypeptide receptor 1 isoform X1; Belongs to the G-protein coupled receptor 2 family. (459 aa)
PRKAR1BcAMP-dependent protein kinase type I-beta regulatory subunit. (391 aa)
VIPR2Vasoactive intestinal polypeptide receptor 2 isoform X1; Belongs to the G-protein coupled receptor 2 family. (442 aa)
DRD1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (446 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GPR15G-protein coupled receptor 15; Belongs to the G-protein coupled receptor 1 family. (360 aa)
THAP9DNA transposase THAP9. (902 aa)
ARRB1Beta-arrestin-1 isoform X1. (422 aa)
PDE2APhosphodiesterase. (943 aa)
PDE1APhosphodiesterase. (531 aa)
CALCRLCalcitonin gene-related peptide type 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
GPR21Probable G-protein coupled receptor 21; Belongs to the G-protein coupled receptor 1 family. (349 aa)
GPR25Probable G-protein coupled receptor 25; Belongs to the G-protein coupled receptor 1 family. (368 aa)
CNBD2Cyclic nucleotide-binding domain-containing protein 2 isoform X1. (583 aa)
GHRHSomatoliberin. (106 aa)
ADRBK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
CALCRCalcitonin receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (478 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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