STRINGSTRING
IFT57 IFT57 ARRB1 ARRB1 GAS8 GAS8 VCP VCP PSMB7 PSMB7 PSMF1 PSMF1 CNBD2 CNBD2 PSMB10 PSMB10 PSMD7 PSMD7 DISP1 DISP1 INTU INTU ADRBK1 ADRBK1 SMURF1 SMURF1 PSMC1 PSMC1 IFT172 IFT172 ADCY3 ADCY3 PTRHD1 PTRHD1 PSMB3 PSMB3 PSMD3 PSMD3 SPOP SPOP IFT122 IFT122 RPGRIP1L RPGRIP1L PSMD9 PSMD9 UBC UBC PSMD1 PSMD1 WDR19 WDR19 PSMC4 PSMC4 PSMD8 PSMD8 NUMBL NUMBL TTC21B TTC21B RBX1 RBX1 MKS1 MKS1 KIAA0141 KIAA0141 SMO SMO DERL2 DERL2 ARRB2 ARRB2 PSMB6 PSMB6 PRKACA PRKACA PRKAR2A PRKAR2A NUMB NUMB PSMC3 PSMC3 PSMD11 PSMD11 PSMC6 PSMC6 PSMA6 PSMA6 GLIS1 GLIS1 DISP2 DISP2 THAP7 THAP7 DHH DHH LOC101374307 LOC101374307 IFT88 IFT88 SPATA5 SPATA5 GLI1 GLI1 BTRC BTRC PSMB5 PSMB5 PSME2 PSME2 PSMB11 PSMB11 PSMC2 PSMC2 PSMB2 PSMB2 IHH IHH SEL1L3 SEL1L3 PDIA2 PDIA2 IFT140 IFT140 ADCY9 ADCY9 SHH SHH GSK3B GSK3B PSMA4 PSMA4 RPS27A RPS27A PSME4 PSME4 PSMD13 PSMD13 GPC5 GPC5 PSMD4 PSMD4 PSMB4 PSMB4 NOTUM NOTUM LOC101376426 LOC101376426 LOC101363792 LOC101363792 SYVN1 SYVN1 BOC BOC PSMD10 PSMD10 DZIP1L DZIP1L CCDC13 CCDC13 EVC2 EVC2 TULP3 TULP3 OFD1 OFD1 ADCY1 ADCY1 ADCY7 ADCY7 ADCY10 ADCY10 ULK3 ULK3 ITCH ITCH PSMC5 PSMC5 SKP1 SKP1 LOC101383782 LOC101383782 UBA52 UBA52 CSNK1A1 CSNK1A1 ERLEC1 ERLEC1 ADCY4 ADCY4 SUFU SUFU PSME1 PSME1 ADCY6 ADCY6 OS9 OS9 LOC101383572 LOC101383572 KIF7 KIF7 ADCY5 ADCY5 LOC101374370 LOC101374370 SCUBE2 SCUBE2 TUB TUB IQCE IQCE IFT52 IFT52 LOC101371369 LOC101371369 PSMD12 PSMD12 LOC101386062 LOC101386062 DYNC2H1 DYNC2H1 P4HB P4HB KXD1 KXD1 GLI2 GLI2 WDR35 WDR35 PRKAR1A PRKAR1A SMURF2 SMURF2 THAP6 THAP6 PSMD2 PSMD2 PSMA5 PSMA5 CUL3 CUL3 PTCH1 PTCH1 PSMB8 PSMB8 PSMB9 PSMB9 TULP1 TULP1 GLIS3 GLIS3 GSK3A GSK3A KIF3A KIF3A GPR161 GPR161 SPATA5L1 SPATA5L1 DZIP1 DZIP1 CDON CDON HHAT HHAT CUL1 CUL1 FOPNL FOPNL ADCY8 ADCY8 FUZ FUZ PSMA7 PSMA7 PSMD14 PSMD14 PSME3 PSME3 PSMD6 PSMD6 PSMA2 PSMA2 GAS1 GAS1 PTCHD2 PTCHD2 GLI3 GLI3 PSMA8 PSMA8 CDC73 CDC73 PSMD5 PSMD5 HHIP HHIP PRKAR2B PRKAR2B LOC101378396 LOC101378396 TTC21A TTC21A LRP2BP LRP2BP SEL1L2 SEL1L2 EFCAB7 EFCAB7 PDCD2 PDCD2 PSMB1 PSMB1 SPOPL SPOPL PRKACB PRKACB PDCD2L PDCD2L EVC EVC HHATL HHATL PRKAR1B PRKAR1B SEL1L SEL1L TULP2 TULP2 ADCY2 ADCY2 PSMA3 PSMA3 PSMA1 PSMA1 THAP9 THAP9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IFT57Intraflagellar transport protein 57 homolog. (429 aa)
ARRB1Beta-arrestin-1 isoform X1. (422 aa)
GAS8Growth arrest-specific protein 8. (453 aa)
VCPTransitional endoplasmic reticulum ATPase isoform X1; Belongs to the AAA ATPase family. (806 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMF1Proteasome inhibitor PI31 subunit. (271 aa)
CNBD2Cyclic nucleotide-binding domain-containing protein 2 isoform X1. (583 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (324 aa)
DISP1Protein dispatched homolog 1. (1525 aa)
INTUProtein inturned. (942 aa)
ADRBK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
PSMC126S protease regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa)
IFT172Intraflagellar transport protein 172 homolog. (1749 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (535 aa)
SPOPSpeckle-type POZ protein isoform X1. (374 aa)
IFT122Intraflagellar transport protein 122 homolog isoform X1. (1235 aa)
RPGRIP1LProtein fantom. (1278 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
UBCpolyubiquitin-C. (229 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
WDR19WD repeat-containing protein 19. (1342 aa)
PSMC426S protease regulatory subunit 6B isoform X1; Belongs to the AAA ATPase family. (418 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (351 aa)
NUMBLNumb-like protein isoform X1. (590 aa)
TTC21BTetratricopeptide repeat protein 21B. (1316 aa)
RBX1E3 ubiquitin-protein ligase RBX1 isoform X1. (116 aa)
MKS1Meckel syndrome type 1 protein. (559 aa)
KIAA0141Death ligand signal enhancer. (520 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
ARRB2Beta-arrestin-2 isoform X1. (420 aa)
PSMB6Proteasome subunit beta. (239 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
PRKAR2AcAMP-dependent protein kinase type II-alpha regulatory subunit isoform X1. (401 aa)
NUMBProtein numb homolog isoform X1. (653 aa)
PSMC326S protease regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (439 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (452 aa)
PSMC626S protease regulatory subunit 10B isoform X1; Belongs to the AAA ATPase family. (403 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
GLIS1Zinc finger protein GLIS1. (798 aa)
DISP2Protein dispatched homolog 2. (1397 aa)
THAP7THAP domain-containing protein 7. (313 aa)
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
LOC101374307S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
IFT88Intraflagellar transport protein 88 homolog. (825 aa)
SPATA5Spermatogenesis-associated protein 5. (701 aa)
GLI1Zinc finger protein GLI1 isoform X1. (1105 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (605 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSME2Proteasome activator complex subunit 2 isoform X1. (239 aa)
PSMB11Proteasome subunit beta. (285 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PSMB2Proteasome subunit beta. (201 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
SEL1L3Protein sel-1 homolog 3. (1131 aa)
PDIA2Protein disulfide-isomerase A2. (524 aa)
IFT140Intraflagellar transport protein 140 homolog. (1459 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
PSME4Proteasome activator complex subunit 4. (1843 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
GPC5Glypican-5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (673 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4. (377 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
NOTUMPalmitoleoyl-protein carboxylesterase NOTUM. (499 aa)
LOC101376426Ubiquitin-like. (101 aa)
LOC101363792Adenylate cyclase type 10-like. (1182 aa)
SYVN1E3 ubiquitin-protein ligase synoviolin. (611 aa)
BOCBrother of CDO isoform X1. (1154 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
DZIP1LZinc finger protein DZIP1L. (774 aa)
CCDC13Coiled-coil domain-containing protein 13. (730 aa)
EVC2Limbin. (1300 aa)
TULP3Tubby-related protein 3; Belongs to the TUB family. (442 aa)
OFD1Oral-facial-digital syndrome 1 protein. (956 aa)
ADCY1Adenylate cyclase type 1. (907 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ADCY10Adenylate cyclase type 10 isoform X1. (1623 aa)
ULK3Serine/threonine-protein kinase ULK3 isoform X1; Belongs to the protein kinase superfamily. (496 aa)
ITCHE3 ubiquitin-protein ligase. (865 aa)
PSMC526S protease regulatory subunit 8 isoform X1; Belongs to the AAA ATPase family. (409 aa)
SKP1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (117 aa)
LOC101383782Proteasome subunit alpha type. (263 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X1. (183 aa)
CSNK1A1Casein kinase I isoform alpha isoform X1; Belongs to the protein kinase superfamily. (365 aa)
ERLEC1Endoplasmic reticulum lectin 1 isoform X1. (539 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (485 aa)
PSME1Proteasome activator complex subunit 1 isoform X1. (249 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
OS9Protein OS-9 isoform X1. (668 aa)
LOC101383572LOW QUALITY PROTEIN: protein numb homolog. (398 aa)
KIF7Kinesin-like protein KIF7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1263 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
LOC101374370LOW QUALITY PROTEIN: EF-hand calcium-binding domain-containing protein 7-like. (663 aa)
SCUBE2Signal peptide, CUB and EGF-like domain-containing protein 2 isoform X1. (1025 aa)
TUBTubby-like protein; Belongs to the TUB family. (617 aa)
IQCEIQ domain-containing protein E. (672 aa)
IFT52Intraflagellar transport protein 52 homolog isoform X1. (446 aa)
LOC101371369Polyubiquitin. (153 aa)
PSMD12LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 12. (584 aa)
LOC101386062Ubiquitin-like. (109 aa)
DYNC2H1Cytoplasmic dynein 2 heavy chain 1 isoform X1. (4314 aa)
P4HBProtein disulfide-isomerase. (510 aa)
KXD1kxDL motif-containing protein 1 isoform X1. (262 aa)
GLI2Zinc finger protein GLI2. (1586 aa)
WDR35WD repeat-containing protein 35; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking. (1181 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (381 aa)
SMURF2E3 ubiquitin-protein ligase. (748 aa)
THAP6THAP domain-containing protein 6. (222 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
CUL3Cullin-3 isoform X1; Belongs to the cullin family. (768 aa)
PTCH1Protein patched homolog 1 isoform X1. (1452 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMB9Proteasome subunit beta. (209 aa)
TULP1Tubby-like protein; Belongs to the TUB family. (546 aa)
GLIS3Zinc finger protein GLIS3. (933 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (483 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (726 aa)
GPR161G-protein coupled receptor 161 isoform X1; Belongs to the G-protein coupled receptor 1 family. (549 aa)
SPATA5L1Spermatogenesis-associated protein 5-like protein 1. (755 aa)
DZIP1Zinc finger protein DZIP1. (866 aa)
CDONCell adhesion molecule-related/down-regulated by oncogenes. (1256 aa)
HHATProtein-cysteine N-palmitoyltransferase HHAT; Belongs to the membrane-bound acyltransferase family. (493 aa)
CUL1Cullin-1; Belongs to the cullin family. (776 aa)
FOPNLlisH domain-containing protein FOPNL isoform X1. (174 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
FUZProtein fuzzy homolog isoform X1. (418 aa)
PSMA7Proteasome subunit alpha type. (254 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
PSME3Proteasome activator complex subunit 3 isoform X1. (315 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (363 aa)
PSMA2Proteasome subunit alpha type. (295 aa)
GAS1Growth arrest-specific protein 1. (346 aa)
PTCHD2Patched domain-containing protein 2. (1392 aa)
GLI3Transcriptional activator GLI3. (1592 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
CDC73Parafibromin. (531 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5 isoform X1. (504 aa)
HHIPHedgehog-interacting protein. (700 aa)
PRKAR2BcAMP-dependent protein kinase type II-beta regulatory subunit. (417 aa)
LOC101378396Uncharacterized protein ENSP00000372125. (313 aa)
TTC21ATetratricopeptide repeat protein 21A isoform X1. (1320 aa)
LRP2BPLRP2-binding protein. (348 aa)
SEL1L2Protein sel-1 homolog 2. (575 aa)
EFCAB7EF-hand calcium-binding domain-containing protein 7. (629 aa)
PDCD2Programmed cell death protein 2 isoform X1. (344 aa)
PSMB1Proteasome subunit beta. (241 aa)
SPOPLSpeckle-type POZ protein-like isoform X1. (392 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa)
PDCD2LProgrammed cell death protein 2-like. (366 aa)
EVCEllis-van Creveld syndrome protein. (1043 aa)
HHATLProtein-cysteine N-palmitoyltransferase HHAT-like protein; Belongs to the membrane-bound acyltransferase family. (504 aa)
PRKAR1BcAMP-dependent protein kinase type I-beta regulatory subunit. (391 aa)
SEL1LProtein sel-1 homolog 1. (794 aa)
TULP2LOW QUALITY PROTEIN: tubby-related protein 2; Belongs to the TUB family. (507 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMA1Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (382 aa)
THAP9DNA transposase THAP9. (902 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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