STRINGSTRING
RBX1 RBX1 NUMBL NUMBL PSMD8 PSMD8 PSMC4 PSMC4 WDR19 WDR19 PSMD1 PSMD1 UBC UBC PSMD9 PSMD9 RPGRIP1L RPGRIP1L IFT122 IFT122 PSMD3 PSMD3 PSMB3 PSMB3 PTRHD1 PTRHD1 ADCY3 ADCY3 IFT172 IFT172 PSMC1 PSMC1 INTU INTU PSMD7 PSMD7 PSMB10 PSMB10 CNBD2 CNBD2 PSMF1 PSMF1 PSMB7 PSMB7 THAP9 THAP9 IFT57 IFT57 LOC101386062 LOC101386062 DYNC2H1 DYNC2H1 PSMC6 PSMC6 PSMA1 PSMA1 PSMA3 PSMA3 ADCY2 ADCY2 TULP2 TULP2 PRKAR1B PRKAR1B PDCD2L PDCD2L PRKACB PRKACB PSMB1 PSMB1 PDCD2 PDCD2 TTC21A TTC21A LOC101378396 LOC101378396 PRKAR2B PRKAR2B PSMD5 PSMD5 PSMA8 PSMA8 GLI3 GLI3 PSMA2 PSMA2 PSMD6 PSMD6 PSME3 PSME3 PSMD14 PSMD14 PSMA7 PSMA7 FUZ FUZ ADCY8 ADCY8 FOPNL FOPNL UBA52 UBA52 LOC101383782 LOC101383782 SKP1 SKP1 PSMC5 PSMC5 ITCH ITCH ADCY10 ADCY10 ADCY7 ADCY7 ADCY1 ADCY1 OFD1 OFD1 TULP3 TULP3 PSMD10 PSMD10 LOC101363792 LOC101363792 LOC101376426 LOC101376426 CUL1 CUL1 GPR161 GPR161 KIF3A KIF3A GSK3A GSK3A GLIS3 GLIS3 TULP1 TULP1 PSMB9 PSMB9 PSMB8 PSMB8 PTCH1 PTCH1 PSMA5 PSMA5 PSMD2 PSMD2 THAP6 THAP6 PRKAR1A PRKAR1A WDR35 WDR35 GLI2 GLI2 KXD1 KXD1 PSMB4 PSMB4 PSMD4 PSMD4 PSMD13 PSMD13 PSME4 PSME4 RPS27A RPS27A PSMA4 PSMA4 GSK3B GSK3B ADCY9 ADCY9 IFT140 IFT140 PSMB2 PSMB2 PSMC2 PSMC2 PSMB11 PSMB11 PSME2 PSME2 PSMB5 PSMB5 BTRC BTRC GLI1 GLI1 IFT88 IFT88 LOC101374307 LOC101374307 THAP7 THAP7 GLIS1 GLIS1 PSMA6 PSMA6 PSMD11 PSMD11 PSMC3 PSMC3 NUMB NUMB PRKAR2A PRKAR2A PRKACA PRKACA PSMB6 PSMB6 SMO SMO MKS1 MKS1 TTC21B TTC21B CSNK1A1 CSNK1A1 ADCY4 ADCY4 SUFU SUFU PSME1 PSME1 ADCY6 ADCY6 LOC101383572 LOC101383572 ADCY5 ADCY5 TUB TUB IFT52 IFT52 LOC101371369 LOC101371369 PSMD12 PSMD12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RBX1E3 ubiquitin-protein ligase RBX1 isoform X1. (116 aa)
NUMBLNumb-like protein isoform X1. (590 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (351 aa)
PSMC426S protease regulatory subunit 6B isoform X1; Belongs to the AAA ATPase family. (418 aa)
WDR19WD repeat-containing protein 19. (1342 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
UBCpolyubiquitin-C. (229 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
RPGRIP1LProtein fantom. (1278 aa)
IFT122Intraflagellar transport protein 122 homolog isoform X1. (1235 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (535 aa)
PSMB3Proteasome subunit beta. (205 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
IFT172Intraflagellar transport protein 172 homolog. (1749 aa)
PSMC126S protease regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa)
INTUProtein inturned. (942 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (324 aa)
PSMB10Proteasome subunit beta. (273 aa)
CNBD2Cyclic nucleotide-binding domain-containing protein 2 isoform X1. (583 aa)
PSMF1Proteasome inhibitor PI31 subunit. (271 aa)
PSMB7Proteasome subunit beta. (277 aa)
THAP9DNA transposase THAP9. (902 aa)
IFT57Intraflagellar transport protein 57 homolog. (429 aa)
LOC101386062Ubiquitin-like. (109 aa)
DYNC2H1Cytoplasmic dynein 2 heavy chain 1 isoform X1. (4314 aa)
PSMC626S protease regulatory subunit 10B isoform X1; Belongs to the AAA ATPase family. (403 aa)
PSMA1Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (382 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
TULP2LOW QUALITY PROTEIN: tubby-related protein 2; Belongs to the TUB family. (507 aa)
PRKAR1BcAMP-dependent protein kinase type I-beta regulatory subunit. (391 aa)
PDCD2LProgrammed cell death protein 2-like. (366 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa)
PSMB1Proteasome subunit beta. (241 aa)
PDCD2Programmed cell death protein 2 isoform X1. (344 aa)
TTC21ATetratricopeptide repeat protein 21A isoform X1. (1320 aa)
LOC101378396Uncharacterized protein ENSP00000372125. (313 aa)
PRKAR2BcAMP-dependent protein kinase type II-beta regulatory subunit. (417 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5 isoform X1. (504 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
GLI3Transcriptional activator GLI3. (1592 aa)
PSMA2Proteasome subunit alpha type. (295 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (363 aa)
PSME3Proteasome activator complex subunit 3 isoform X1. (315 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
PSMA7Proteasome subunit alpha type. (254 aa)
FUZProtein fuzzy homolog isoform X1. (418 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
FOPNLlisH domain-containing protein FOPNL isoform X1. (174 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X1. (183 aa)
LOC101383782Proteasome subunit alpha type. (263 aa)
SKP1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (117 aa)
PSMC526S protease regulatory subunit 8 isoform X1; Belongs to the AAA ATPase family. (409 aa)
ITCHE3 ubiquitin-protein ligase. (865 aa)
ADCY10Adenylate cyclase type 10 isoform X1. (1623 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ADCY1Adenylate cyclase type 1. (907 aa)
OFD1Oral-facial-digital syndrome 1 protein. (956 aa)
TULP3Tubby-related protein 3; Belongs to the TUB family. (442 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
LOC101363792Adenylate cyclase type 10-like. (1182 aa)
LOC101376426Ubiquitin-like. (101 aa)
CUL1Cullin-1; Belongs to the cullin family. (776 aa)
GPR161G-protein coupled receptor 161 isoform X1; Belongs to the G-protein coupled receptor 1 family. (549 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (726 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (483 aa)
GLIS3Zinc finger protein GLIS3. (933 aa)
TULP1Tubby-like protein; Belongs to the TUB family. (546 aa)
PSMB9Proteasome subunit beta. (209 aa)
PSMB8Proteasome subunit beta. (276 aa)
PTCH1Protein patched homolog 1 isoform X1. (1452 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
THAP6THAP domain-containing protein 6. (222 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (381 aa)
WDR35WD repeat-containing protein 35; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking. (1181 aa)
GLI2Zinc finger protein GLI2. (1586 aa)
KXD1kxDL motif-containing protein 1 isoform X1. (262 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4. (377 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
PSME4Proteasome activator complex subunit 4. (1843 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
IFT140Intraflagellar transport protein 140 homolog. (1459 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PSMB11Proteasome subunit beta. (285 aa)
PSME2Proteasome activator complex subunit 2 isoform X1. (239 aa)
PSMB5Proteasome subunit beta. (263 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (605 aa)
GLI1Zinc finger protein GLI1 isoform X1. (1105 aa)
IFT88Intraflagellar transport protein 88 homolog. (825 aa)
LOC101374307S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
THAP7THAP domain-containing protein 7. (313 aa)
GLIS1Zinc finger protein GLIS1. (798 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (452 aa)
PSMC326S protease regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (439 aa)
NUMBProtein numb homolog isoform X1. (653 aa)
PRKAR2AcAMP-dependent protein kinase type II-alpha regulatory subunit isoform X1. (401 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
PSMB6Proteasome subunit beta. (239 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
MKS1Meckel syndrome type 1 protein. (559 aa)
TTC21BTetratricopeptide repeat protein 21B. (1316 aa)
CSNK1A1Casein kinase I isoform alpha isoform X1; Belongs to the protein kinase superfamily. (365 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (485 aa)
PSME1Proteasome activator complex subunit 1 isoform X1. (249 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
LOC101383572LOW QUALITY PROTEIN: protein numb homolog. (398 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
TUBTubby-like protein; Belongs to the TUB family. (617 aa)
IFT52Intraflagellar transport protein 52 homolog isoform X1. (446 aa)
LOC101371369Polyubiquitin. (153 aa)
PSMD12LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 12. (584 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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