11 items (Odobenus rosmarus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	INSR	Tyrosine-protein kinase receptor. (1381 aa)
	SOS1	Son of sevenless homolog 1 isoform X1. (1333 aa)
	IRS1	Insulin receptor substrate 1. (1233 aa)
	GRB10	Growth factor receptor-bound protein 10. (586 aa)
	IRS2	Insulin receptor substrate 2. (1327 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
	LOC101378833	Insulin receptor substrate 2-like. (528 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
	GRB2	Growth factor receptor-bound protein 2 isoform X1. (217 aa)
	SHC1	SHC-transforming protein 1 isoform X1. (609 aa)

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GRB10	GRB2	A0A2U3WZI7	A0A2U3VHU3	Growth factor receptor-bound protein 10.	Growth factor receptor-bound protein 2 isoform X1.	0.669
GRB10	INS	A0A2U3WZI7	A0A2U3W6R9	Growth factor receptor-bound protein 10.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.746
GRB10	INSR	A0A2U3WZI7	A0A2U3WSM4	Growth factor receptor-bound protein 10.	Tyrosine-protein kinase receptor.	0.985
GRB10	IRS1	A0A2U3WZI7	A0A2U3WLJ5	Growth factor receptor-bound protein 10.	Insulin receptor substrate 1.	0.490
GRB10	IRS2	A0A2U3WZI7	A0A2U3WL54	Growth factor receptor-bound protein 10.	Insulin receptor substrate 2.	0.490
GRB10	LOC101378833	A0A2U3WZI7	A0A2U3VUV5	Growth factor receptor-bound protein 10.	Insulin receptor substrate 2-like.	0.490
GRB10	SHC1	A0A2U3WZI7	A0A2U3ZJC4	Growth factor receptor-bound protein 10.	SHC-transforming protein 1 isoform X1.	0.411
GRB2	GRB10	A0A2U3VHU3	A0A2U3WZI7	Growth factor receptor-bound protein 2 isoform X1.	Growth factor receptor-bound protein 10.	0.669
GRB2	INS	A0A2U3VHU3	A0A2U3W6R9	Growth factor receptor-bound protein 2 isoform X1.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.703
GRB2	INSR	A0A2U3VHU3	A0A2U3WSM4	Growth factor receptor-bound protein 2 isoform X1.	Tyrosine-protein kinase receptor.	0.967
GRB2	IRS1	A0A2U3VHU3	A0A2U3WLJ5	Growth factor receptor-bound protein 2 isoform X1.	Insulin receptor substrate 1.	0.983
GRB2	IRS2	A0A2U3VHU3	A0A2U3WL54	Growth factor receptor-bound protein 2 isoform X1.	Insulin receptor substrate 2.	0.983
GRB2	LOC101378833	A0A2U3VHU3	A0A2U3VUV5	Growth factor receptor-bound protein 2 isoform X1.	Insulin receptor substrate 2-like.	0.983
GRB2	MAPK1	A0A2U3VHU3	A0A2U3VYF5	Growth factor receptor-bound protein 2 isoform X1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.595
GRB2	MAPK3	A0A2U3VHU3	A0A2U3VPZ0	Growth factor receptor-bound protein 2 isoform X1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.457
GRB2	SHC1	A0A2U3VHU3	A0A2U3ZJC4	Growth factor receptor-bound protein 2 isoform X1.	SHC-transforming protein 1 isoform X1.	0.999
GRB2	SOS1	A0A2U3VHU3	A0A2U3WM57	Growth factor receptor-bound protein 2 isoform X1.	Son of sevenless homolog 1 isoform X1.	0.999
INS	GRB10	A0A2U3W6R9	A0A2U3WZI7	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Growth factor receptor-bound protein 10.	0.746
INS	GRB2	A0A2U3W6R9	A0A2U3VHU3	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Growth factor receptor-bound protein 2 isoform X1.	0.703
INS	INSR	A0A2U3W6R9	A0A2U3WSM4	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.999