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| | LAMTOR3 | Ragulator complex protein LAMTOR3. (124 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | ARRB1 | Beta-arrestin-1 isoform X1. (422 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (544 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa) |
| | DUSP1 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | CACNA1S | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa) |
| | PTPN7 | Tyrosine-protein phosphatase non-receptor type 7. (360 aa) |
| | ELK4 | ETS domain-containing protein Elk-4. (430 aa) |
| | AREG | Amphiregulin isoform X1. (253 aa) |
| | ANGPT4 | Angiopoietin-4. (498 aa) |
| | CACNB2 | Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (661 aa) |
| | NFATC3 | Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1072 aa) |
| | HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa) |
| | EFNA5 | ephrin-A5; Belongs to the ephrin family. (228 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | RELA | Transcription factor p65. (539 aa) |
| | MAP4K2 | Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa) |
| | RASGRP2 | RAS guanyl-releasing protein 2. (608 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (188 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa) |
| | RPS6KA4 | Ribosomal protein S6 kinase. (772 aa) |
| | RAC1 | Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa) |
| | PDGFC | Platelet-derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | GNA12 | Guanine nucleotide-binding protein subunit alpha-12 isoform X1. (382 aa) |
| | GRB2 | Growth factor receptor-bound protein 2 isoform X1. (217 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (820 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (798 aa) |
| | RPS6KA1 | Ribosomal protein S6 kinase. (744 aa) |
| | MAP3K6 | Mitogen-activated protein kinase kinase kinase 6. (1452 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1281 aa) |
| | CACNA1G | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2379 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (161 aa) |
| | MKNK2 | MAP kinase-interacting serine/threonine-protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. (484 aa) |
| | EFNA2 | ephrin-A2; Belongs to the ephrin family. (214 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | IRAK4 | Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (808 aa) |
| | KDR | Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | MAP4K1 | Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa) |
| | RASGRP4 | RAS guanyl-releasing protein 4. (673 aa) |
| | TGFB1 | Transforming growth factor beta-1. (287 aa) |
| | TAOK3 | Serine/threonine-protein kinase TAO3 isoform X1. (898 aa) |
| | ARAF | Serine/threonine-protein kinase A-Raf. (606 aa) |
| | ELK1 | ETS domain-containing protein Elk-1. (435 aa) |
| | CACNA1F | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1983 aa) |
| | EPHA2 | Ephrin type-A receptor 2. (975 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | TAOK2 | Serine/threonine-protein kinase TAO2 isoform X1. (1236 aa) |
| | RASA2 | Ras GTPase-activating protein 2 isoform X1. (852 aa) |
| | ATF4 | Cyclic AMP-dependent transcription factor ATF-4. (351 aa) |
| | TAB1 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (504 aa) |
| | CACNA1I | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2143 aa) |
| | PPP3R1 | Calcineurin subunit B type 1 isoform X1. (170 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (373 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | FLNC | filamin-C isoform X1. (2719 aa) |
| | CDC25B | M-phase inducer phosphatase 2 isoform X1. (574 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | ARRB2 | Beta-arrestin-2 isoform X1. (420 aa) |
| | TGFA | Protransforming growth factor alpha isoform X1. (160 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | CACNG3 | Voltage-dependent calcium channel gamma-3 subunit. (315 aa) |
| | ECSIT | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform X1. (430 aa) |
| | CACNA1A | Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2501 aa) |
| | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa) |
| | LOC101368814 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | HSPB1 | Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (207 aa) |
| | MAPKAPK3 | MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa) |
| | CACNA2D2 | Voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1. (1153 aa) |
| | FOS | Proto-oncogene c-Fos isoform X1. (380 aa) |
| | PGF | Placenta growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa) |
| | TGFB3 | Transforming growth factor beta-3. (461 aa) |
| | NF1 | Neurofibromin isoform X1. (2841 aa) |
| | TAOK1 | Serine/threonine-protein kinase TAO1 isoform X1. (1001 aa) |
| | MAPK8IP1 | C-Jun-amino-terminal kinase-interacting protein 1. (704 aa) |
| | NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (270 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (265 aa) |
| | DUSP2 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (313 aa) |
| | LOC101379027 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | PPM1B | Protein phosphatase 1B isoform X1. (484 aa) |
| | PLA2G4E | Phospholipase A2. (864 aa) |
| | PLA2G4F | Phospholipase A2. (875 aa) |
| | PLA2G4D | Phospholipase A2. (817 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | CRKL | Crk-like protein. (303 aa) |
| | MKNK1 | MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (421 aa) |
| | NR4A1 | Nuclear receptor subfamily 4 group A member 1. (598 aa) |
| | CACNB3 | Voltage-dependent L-type calcium channel subunit beta-3 isoform X1. (484 aa) |
| | PPP5C | Serine/threonine-protein phosphatase. (499 aa) |
| | RELB | Transcription factor RelB. (566 aa) |
| | MAP3K4 | Mitogen-activated protein kinase kinase kinase 4 isoform X1. (1602 aa) |
| | NGF | Beta-nerve growth factor; Belongs to the NGF-beta family. (241 aa) |
| | RAP1A | Ras-related protein Rap-1A. (184 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | RPS6KA3 | Ribosomal protein S6 kinase. (740 aa) |
| | ERBB3 | Receptor tyrosine-protein kinase erbB-3. (1339 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa) |
| | NFKB2 | Nuclear factor NF-kappa-B p100 subunit. (900 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | STK3 | Serine/threonine-protein kinase 3 isoform X1. (491 aa) |
| | MAP4K4 | Mitogen-activated protein kinase kinase kinase kinase 4 isoform X1. (1270 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1098 aa) |
| | CSF1R | Macrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (966 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (796 aa) |
| | EFNA1 | ephrin-A1 isoform X1; Belongs to the ephrin family. (206 aa) |
| | EFNA3 | ephrin-A3 isoform X1; Belongs to the ephrin family. (238 aa) |
| | CACNA1H | Voltage-dependent T-type calcium channel subunit alpha-1H. (2347 aa) |
| | MAPK8IP3 | C-Jun-amino-terminal kinase-interacting protein 3 isoform X1. (1335 aa) |
| | MEF2C | Myocyte-specific enhancer factor 2C isoform X1. (483 aa) |
| | RASGRF1 | Ras-specific guanine nucleotide-releasing factor 1. (1257 aa) |
| | RASGRP3 | Ras guanyl-releasing protein 3 isoform X1. (694 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | IGF2 | LOW QUALITY PROTEIN: insulin-like growth factor II. (198 aa) |
| | DUSP8 | Dual specificity protein phosphatase 8. (626 aa) |
| | INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | ANGPT1 | Angiopoietin-1 isoform X1. (498 aa) |
| | TAB2 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa) |
| | CRK | Adapter molecule crk isoform X1. (304 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | RAC3 | Ras-related C3 botulinum toxin substrate 3. (192 aa) |
| | JUND | LOW QUALITY PROTEIN: transcription factor jun-D. (464 aa) |
| | MAP2K3 | Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | RASGRF2 | Ras-specific guanine nucleotide-releasing factor 2. (1215 aa) |
| | ANGPT2 | Angiopoietin-2 isoform X1. (495 aa) |
| | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | MAP3K3 | Mitogen-activated protein kinase kinase kinase 3 isoform X1. (657 aa) |
| | RAP1B | Ras-related protein Rap-1b isoform X1. (184 aa) |
| | PTPRR | Receptor-type tyrosine-protein phosphatase R isoform X1. (655 aa) |
| | MAP3K12 | Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (892 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (421 aa) |
| | CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2190 aa) |
| | CACNA2D4 | Voltage-dependent calcium channel subunit alpha-2/delta-4. (1121 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (553 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (270 aa) |
| | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (955 aa) |
| | DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa) |
| | NTRK2 | Tyrosine-protein kinase receptor. (838 aa) |
| | LOC101381295 | Mitogen-activated protein kinase kinase kinase MLT isoform X1. (800 aa) |
| | DAXX | Death domain-associated protein 6 isoform X1. (757 aa) |
| | SOS2 | Son of sevenless homolog 2 isoform X1. (1333 aa) |
| | SRF | Serum response factor isoform X1. (508 aa) |
| | MAP3K2 | Mitogen-activated protein kinase kinase kinase 2. (620 aa) |
| | DUSP4 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa) |
| | DUSP10 | Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | MET | Hepatocyte growth factor receptor. (1382 aa) |
| | BDNF | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (255 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1508 aa) |
| | DUSP9 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (380 aa) |
| | IRAK1 | Interleukin-1 receptor-associated kinase 1 isoform X1. (724 aa) |
| | HSPA2 | Heat shock-related 70 kDa protein 2; Belongs to the heat shock protein 70 family. (638 aa) |
| | MAX | Protein max isoform X1. (190 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | CACNG7 | Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa) |
| | CACNG8 | Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (489 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | CACNG6 | Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (260 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | RASGRP1 | RAS guanyl-releasing protein 1 isoform X1. (797 aa) |
| | MAPK8IP2 | C-Jun-amino-terminal kinase-interacting protein 2. (831 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) |
| | FLT3LG | Fms-related tyrosine kinase 3 ligand. (294 aa) |
| | RRAS | Ras-related protein R-Ras. (218 aa) |
| | SOS1 | Son of sevenless homolog 1 isoform X1. (1333 aa) |
| | MAP4K3 | Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (894 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1366 aa) |
| | RAC2 | Ras-related C3 botulinum toxin substrate 2. (192 aa) |
| | DUSP16 | Dual specificity protein phosphatase 16. (666 aa) |
| | MAPT | Microtubule-associated protein. (802 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa) |
| | DUSP5 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa) |
| | CDC42 | Cell division control protein 42 homolog isoform X1. (191 aa) |
| | MAP2K5 | Dual specificity mitogen-activated protein kinase kinase 5 isoform X1; Belongs to the protein kinase superfamily. (448 aa) |
| | MAP2K7 | Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1381 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | FLNB | filamin-B isoform X1. (2633 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (277 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (427 aa) |
| | FLT4 | Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1450 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (503 aa) |
| | NFATC1 | Nuclear factor of activated T-cells, cytoplasmic 1. (823 aa) |
| | IGF1 | Insulin-like growth factor I isoform X1. (187 aa) |
| | MRAS | Ras-related protein M-Ras. (208 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa) |
| | PRKACB | cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa) |
| | HSPA8 | Heat shock cognate 71 kDa protein isoform X1; Belongs to the heat shock protein 70 family. (654 aa) |
| | RPS6KA6 | Ribosomal protein S6 kinase. (744 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (451 aa) |
| | STK4 | Serine/threonine-protein kinase 4 isoform X1. (487 aa) |
| | CACNA2D3 | Voltage-dependent calcium channel subunit alpha-2/delta-3. (997 aa) |
| | PPP3R2 | Calcineurin subunit B type 2. (170 aa) |
| | PDGFA | Platelet-derived growth factor subunit A isoform X1; Belongs to the PDGF/VEGF growth factor family. (211 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa) |
| | FLNA | filamin-A. (2646 aa) |
| | FLT1 | Vascular endothelial growth factor receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) |
| | FLT3 | Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa) |
| | DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa) |
| | JUN | Transcription factor AP-1 isoform X1; Belongs to the bZIP family. (335 aa) |
| | NTF4 | Neurotrophin-4; Belongs to the NGF-beta family. (211 aa) |
| | FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha isoform X1. (165 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | LOC101376406 | Heat shock 70 kDa protein 1; Belongs to the heat shock protein 70 family. (641 aa) |
| | CACNB4 | Voltage-dependent L-type calcium channel subunit beta-4 isoform X1. (519 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | LOC101367134 | GTPase HRas-like. (177 aa) |
| | FIGF | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (353 aa) |
| | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 isoform X4. (563 aa) |
| | RRAS2 | Ras-related protein R-Ras2 isoform X1. (204 aa) |
| | PPM1A | Protein phosphatase 1A isoform X1. (430 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | CACNG4 | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa) |
| | CACNG1 | Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa) |
| | CACNG5 | Voltage-dependent calcium channel gamma-5 subunit. (275 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (245 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa) |
| | TEK | Angiopoietin-1 receptor isoform X1. (1125 aa) |
| | RASA1 | Ras GTPase-activating protein 1. (1039 aa) |
| | MAP3K8 | Mitogen-activated protein kinase kinase kinase 8. (467 aa) |
| | CACNG2 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa) |
| | MAPKAPK2 | MAP kinase-activated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. (402 aa) |
| | PDGFD | Platelet-derived growth factor D. (328 aa) |
| | LOC101366544 | LOW QUALITY PROTEIN: ras-related C3 botulinum toxin substrate 1-like. (145 aa) |
| | RAPGEF2 | Rap guanine nucleotide exchange factor 2 isoform X1. (1644 aa) |
| | STMN1 | Stathmin; Belongs to the stathmin family. (149 aa) |
| | NGFR | Tumor necrosis factor receptor superfamily member 16. (421 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa) |
| | MAPKAPK5 | MAP kinase-activated protein kinase 5 isoform X1. (473 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1090 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | CACNA1E | Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2305 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (982 aa) |
| | PDGFB | Platelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (242 aa) |
| | LOC101375744 | LOW QUALITY PROTEIN: heat shock cognate 71 kDa protein-like; Belongs to the heat shock protein 70 family. (656 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | PLA2G4B | Phospholipase A2. (782 aa) |
| | LOC101371484 | Receptor tyrosine-protein kinase erbB-4. (838 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (856 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (377 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (534 aa) |
| | IL1R1 | Interleukin-1 receptor type 1. (573 aa) |
| | RPS6KA2 | Ribosomal protein S6 kinase. (758 aa) |
| | EFNA4 | ephrin-A4 isoform X1; Belongs to the ephrin family. (206 aa) |
| | HSPA6 | LOW QUALITY PROTEIN: heat shock 70 kDa protein 6; Belongs to the heat shock protein 70 family. (688 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (840 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (806 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1304 aa) |
| | EREG | Proepiregulin isoform X1. (166 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (525 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (587 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa) |
| | MECOM | MDS1 and EVI1 complex locus protein EVI1 isoform X1. (1230 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6. (319 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1. (324 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1210 aa) |
| | DUSP7 | Dual specificity protein phosphatase 7 isoform X1. (427 aa) |
| | LOC105758129 | Voltage-dependent N-type calcium channel subunit alpha-1B-like. (873 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa) |
| | IL1RAP | Interleukin-1 receptor accessory protein. (687 aa) |
| | CACNA2D1 | Voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X1. (1110 aa) |
| | BRAF | Serine/threonine-protein kinase B-raf. (772 aa) |
| | IKBKG | NF-kappa-B essential modulator isoform X1. (457 aa) |
| | HSPA1L | Heat shock 70 kDa protein 1-like isoform X1; Belongs to the heat shock protein 70 family. (661 aa) |
| | MAP2K4 | Dual specificity mitogen-activated protein kinase kinase 4 isoform X1; Belongs to the protein kinase superfamily. (411 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1209 aa) |
| | LOC101362132 | LOW QUALITY PROTEIN: MAP kinase-activated protein kinase 5-like. (699 aa) |
