STRINGSTRING
HES1 HES1 ATXN1L ATXN1L PSEN2 PSEN2 LFNG LFNG JAG2 JAG2 NCOR2 NCOR2 CTBP1 CTBP1 NUMBL NUMBL PSENEN PSENEN DLL3 DLL3 EP300 EP300 KAT2B KAT2B HDAC2 HDAC2 MAML2 MAML2 DVL2 DVL2 DTX2 DTX2 SNW1 SNW1 NUMB NUMB PSEN1 PSEN1 DTX3 DTX3 ADAM17 ADAM17 HEYL HEYL RBPJ RBPJ CREBBP CREBBP HEY2 HEY2 APH1A APH1A CTBP2 CTBP2 RFNG RFNG MAML3 MAML3 ATXN1 ATXN1 HDAC1 HDAC1 DVL3 DVL3 HES5 HES5 DVL1 DVL1 NCSTN NCSTN PTCRA PTCRA NOTCH3 NOTCH3 CIR1 CIR1 DTX4 DTX4 DTX1 DTX1 NOTCH1 NOTCH1 MFNG MFNG APH1B APH1B MAML1 MAML1 DLL1 DLL1 RBPJL RBPJL NOTCH4 NOTCH4 NOTCH2 NOTCH2 DTX3L DTX3L LOC101383572 LOC101383572 DLL4 DLL4 JAG1 JAG1 KAT2A KAT2A HEY1 HEY1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HES1Transcription factor HES-1. (280 aa)
ATXN1LAtaxin-1-like. (688 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (464 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase. (381 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1244 aa)
NCOR2Nuclear receptor corepressor 2. (2520 aa)
CTBP1C-terminal-binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (429 aa)
NUMBLNumb-like protein isoform X1. (590 aa)
PSENENGamma-secretase subunit PEN-2. (101 aa)
DLL3LOW QUALITY PROTEIN: delta-like protein 3. (620 aa)
EP300Histone acetyltransferase p300. (2421 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa)
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
MAML2Mastermind-like protein 2. (1114 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X1. (734 aa)
DTX2Probable E3 ubiquitin-protein ligase DTX2 isoform X1. (701 aa)
SNW1SNW domain-containing protein 1 isoform X1. (536 aa)
NUMBProtein numb homolog isoform X1. (653 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
DTX3Probable E3 ubiquitin-protein ligase DTX3 isoform X1. (352 aa)
ADAM17Disintegrin and metalloproteinase domain-containing protein 17. (822 aa)
HEYLHairy/enhancer-of-split related with YRPW motif-like protein. (328 aa)
RBPJRecombining binding protein suppressor of hairless isoform X1. (500 aa)
CREBBPCREB-binding protein isoform X1. (2433 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
APH1AGamma-secretase subunit APH-1A isoform X1. (265 aa)
CTBP2C-terminal-binding protein 2 isoform X1. (979 aa)
RFNGBeta-1,3-N-acetylglucosaminyltransferase. (348 aa)
MAML3Mastermind-like protein 3. (1109 aa)
ATXN1Ataxin-1. (808 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3 isoform X1. (716 aa)
HES5Transcription factor HES-5. (165 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (693 aa)
NCSTNNicastrin isoform X1. (708 aa)
PTCRAPre T-cell antigen receptor alpha. (334 aa)
NOTCH3Neurogenic locus notch homolog protein 3. (2322 aa)
CIR1Corepressor interacting with RBPJ 1. (467 aa)
DTX4E3 ubiquitin-protein ligase DTX4. (619 aa)
DTX1E3 ubiquitin-protein ligase DTX1. (559 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2567 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (321 aa)
APH1BGamma-secretase subunit APH-1B isoform X1. (257 aa)
MAML1Mastermind-like protein 1. (1023 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
RBPJLRecombining binding protein suppressor of hairless-like protein. (517 aa)
NOTCH4Neurogenic locus notch homolog protein 4 isoform X1. (1996 aa)
NOTCH2Neurogenic locus notch homolog protein 2. (2471 aa)
DTX3LE3 ubiquitin-protein ligase DTX3L. (693 aa)
LOC101383572LOW QUALITY PROTEIN: protein numb homolog. (398 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (716 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1250 aa)
KAT2AHistone acetyltransferase KAT2A isoform X1. (838 aa)
HEY1Hairy/enhancer-of-split related with YRPW motif protein 1 isoform X1. (308 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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