STRINGSTRING
BMPR1B BMPR1B WNT11 WNT11 ID1 ID1 SKIL SKIL ZFHX3 ZFHX3 BMPR2 BMPR2 LEFTY2 LEFTY2 NODAL NODAL FZD1 FZD1 GRB2 GRB2 FGFR1 FGFR1 KAT6A KAT6A ID3 ID3 ACVR1C ACVR1C ACVR1 ACVR1 PCGF2 PCGF2 HOXB1 HOXB1 MAP2K2 MAP2K2 TCF3 TCF3 APC2 APC2 WNT7A WNT7A AKT1 AKT1 FGFR3 FGFR3 PCGF3 PCGF3 AKT2 AKT2 ONECUT1 ONECUT1 MAPK3 MAPK3 HOXA1 HOXA1 MEIS1 MEIS1 PIK3CD PIK3CD OTX1 OTX1 WNT8A WNT8A PIK3CA PIK3CA DVL2 DVL2 PCGF1 PCGF1 FZD9 FZD9 SMAD9 SMAD9 AKT3 AKT3 MAPK1 MAPK1 PIK3R3 PIK3R3 ACVR1B ACVR1B WNT10B WNT10B WNT1 WNT1 WNT2B WNT2B APC APC ACVR2A ACVR2A INHBC INHBC INHBE INHBE ID2 ID2 WNT8B WNT8B PCGF6 PCGF6 FZD6 FZD6 WNT10A WNT10A WNT6 WNT6 AXIN1 AXIN1 GSK3B GSK3B HRAS HRAS LIFR LIFR SETDB1 SETDB1 JARID2 JARID2 WNT16 WNT16 JAK3 JAK3 PIK3R2 PIK3R2 INHBB INHBB FZD5 FZD5 NEUROG1 NEUROG1 SMAD5 SMAD5 AXIN2 AXIN2 ID4 ID4 PAX6 PAX6 HESX1 HESX1 WNT5A WNT5A DVL3 DVL3 WNT5B WNT5B WNT9A WNT9A WNT3A WNT3A FZD2 FZD2 MYF5 MYF5 DVL1 DVL1 JAK2 JAK2 WNT2 WNT2 SMAD2 SMAD2 HOXD1 HOXD1 POU5F1 POU5F1 DUSP9 DUSP9 MAPK11 MAPK11 MAPK12 MAPK12 HAND1 HAND1 KLF4 KLF4 MAPK13 MAPK13 MAPK14 MAPK14 DLX5 DLX5 BMPR1A BMPR1A LHX5 LHX5 SMAD4 SMAD4 STAT3 STAT3 NANOG NANOG ISL1 ISL1 WNT3 WNT3 WNT9B WNT9B INHBA INHBA FZD3 FZD3 WNT4 WNT4 SMAD1 SMAD1 ACVR2B ACVR2B IGF1 IGF1 PIK3CB PIK3CB FZD4 FZD4 MAP2K1 MAP2K1 SMAD3 SMAD3 RIF1 RIF1 LOC101367134 LOC101367134 FZD10 FZD10 WNT7B WNT7B PIK3R1 PIK3R1 IL6ST IL6ST SOX2 SOX2 TBX3 TBX3 FZD8 FZD8 ZIC3 ZIC3 ESX1 ESX1 CTNNB1 CTNNB1 RAF1 RAF1 REST REST SMARCAD1 SMARCAD1 LIF LIF LOC101366870 LOC101366870 NRAS NRAS FGFR4 FGFR4 FGF2 FGF2 FGFR2 FGFR2 LOC105757667 LOC105757667 BMP4 BMP4 IGF1R IGF1R BMI1 BMI1 PCGF5 PCGF5 MYC MYC JAK1 JAK1 FZD7 FZD7 LOC101369997 LOC101369997
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
ID1DNA-binding protein inhibitor ID-1. (154 aa)
SKILSki-like protein isoform X2. (690 aa)
ZFHX3Zinc finger homeobox protein 3 isoform X1. (3690 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
LEFTY2Left-right determination factor. (367 aa)
NODALNodal homolog. (348 aa)
FZD1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (648 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
FGFR1Fibroblast growth factor receptor. (820 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1995 aa)
ID3DNA-binding protein inhibitor ID-3. (119 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
PCGF2Polycomb group RING finger protein 2. (344 aa)
HOXB1Homeobox protein Hox-B1. (301 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
TCF3Transcription factor E2-alpha isoform X1. (654 aa)
APC2Adenomatous polyposis coli protein 2. (2267 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
FGFR3Fibroblast growth factor receptor. (808 aa)
PCGF3Polycomb group RING finger protein 3. (242 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ONECUT1One cut domain family member. (465 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
HOXA1Homeobox protein Hox-A1 isoform X1. (332 aa)
MEIS1Homeobox protein Meis1 isoform X1. (465 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
OTX1Homeobox protein OTX1 isoform X1. (354 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X1. (734 aa)
PCGF1Polycomb group RING finger protein 1. (259 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (597 aa)
SMAD9Mothers against decapentaplegic homolog. (469 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (507 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
APCAdenomatous polyposis coli protein isoform X1. (2844 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
INHBCInhibin beta C chain. (352 aa)
INHBEInhibin beta E chain. (351 aa)
ID2DNA-binding protein inhibitor ID-2. (134 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
PCGF6Polycomb group RING finger protein 6 isoform X1. (349 aa)
FZD6Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
AXIN1Axin-1. (867 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
HRASGTPase HRas isoform X1. (189 aa)
LIFRLeukemia inhibitory factor receptor. (1097 aa)
SETDB1Histone-lysine N-methyltransferase SETDB1 isoform X1. (1297 aa)
JARID2Protein Jumonji. (1249 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
JAK3Tyrosine-protein kinase. (1104 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa)
INHBBInhibin beta B chain. (320 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (590 aa)
NEUROG1Neurogenin-1. (244 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
AXIN2Axin-2 isoform X1. (842 aa)
ID4DNA-binding protein inhibitor ID-4. (161 aa)
PAX6Paired box protein Pax-6 isoform X1. (436 aa)
HESX1Homeobox expressed in ES cells 1. (185 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3 isoform X1. (716 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (693 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
HOXD1Homeobox protein Hox-D1. (326 aa)
POU5F1POU domain protein. (360 aa)
DUSP9Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (380 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
KLF4Krueppel-like factor 4. (486 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
DLX5Homeobox protein DLX-5. (289 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LHX5LIM/homeobox protein Lhx5. (402 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
NANOGHomeobox protein NANOG. (407 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
INHBAInhibin beta A chain. (423 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
IGF1Insulin-like growth factor I isoform X1. (187 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
RIF1Telomere-associated protein RIF1 isoform X1. (2477 aa)
LOC101367134GTPase HRas-like. (177 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
IL6STInterleukin-6 receptor subunit beta isoform X1. (918 aa)
SOX2Transcription factor SOX-2. (320 aa)
TBX3T-box transcription factor TBX3 isoform X1. (747 aa)
FZD8Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (689 aa)
ZIC3Zinc finger protein ZIC 3. (533 aa)
ESX1Homeobox protein ESX1. (402 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
RESTRE1-silencing transcription factor. (1000 aa)
SMARCAD1annotation not available (1028 aa)
LIFLeukemia inhibitory factor isoform X1. (204 aa)
LOC101366870LOW QUALITY PROTEIN: homeobox protein NANOG-like. (300 aa)
NRASGTPase NRas. (189 aa)
FGFR4Fibroblast growth factor receptor. (856 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (377 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
LOC105757667Rhox homeobox family member 1-like. (256 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
IGF1RTyrosine-protein kinase receptor. (1304 aa)
BMI1Polycomb complex protein BMI-1 isoform X1. (326 aa)
PCGF5Polycomb group RING finger protein 5 isoform X1. (281 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
LOC101369997Homeobox expressed in ES cells 1-like. (185 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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