STRINGSTRING
PPP3CA PPP3CA DAPP1 DAPP1 INPPL1 INPPL1 PLCG2 PLCG2 NFATC3 NFATC3 RELA RELA CARD11 CARD11 RAC1 RAC1 GRB2 GRB2 MAP2K2 MAP2K2 AKT1 AKT1 INPP5D INPP5D AKT2 AKT2 MAPK3 MAPK3 PIK3CD PIK3CD PPP3R1 PPP3R1 PIK3CA PIK3CA PRKCB PRKCB FOS FOS NFKBIA NFKBIA AKT3 AKT3 MAPK1 MAPK1 PIK3R3 PIK3R3 NFKB1 NFKB1 CHUK CHUK GSK3B GSK3B RASGRP3 RASGRP3 HRAS HRAS CD81 CD81 RAC3 RAC3 PIK3R2 PIK3R2 VAV3 VAV3 SOS2 SOS2 NFKBIE NFKBIE CD79A CD79A BLNK BLNK PIK3AP1 PIK3AP1 MALT1 MALT1 SYK SYK SOS1 SOS1 RAC2 RAC2 VAV2 VAV2 LOC101370467 LOC101370467 NFATC1 NFATC1 PIK3CB PIK3CB BCL10 BCL10 PTPN6 PTPN6 PPP3R2 PPP3R2 LYN LYN MAP2K1 MAP2K1 NFATC2 NFATC2 JUN JUN LOC101367134 LOC101367134 CR2 CR2 IKBKB IKBKB LOC101372843 LOC101372843 PIK3R1 PIK3R1 CD22 CD22 LOC101366544 LOC101366544 VAV1 VAV1 RAF1 RAF1 NFKBIB NFKBIB CD19 CD19 CD72 CD72 NRAS NRAS PPP3CC PPP3CC CD79B CD79B PPP3CB PPP3CB IKBKG IKBKG LOC101373702 LOC101373702 BTK BTK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP3CASerine/threonine-protein phosphatase. (521 aa)
DAPP1Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide. (280 aa)
INPPL1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1264 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1072 aa)
RELATranscription factor p65. (539 aa)
CARD11Caspase recruitment domain-containing protein 11. (1146 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1188 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PPP3R1Calcineurin subunit B type 1 isoform X1. (170 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
FOSProto-oncogene c-Fos isoform X1. (380 aa)
NFKBIANF-kappa-B inhibitor alpha. (314 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (507 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
RASGRP3Ras guanyl-releasing protein 3 isoform X1. (694 aa)
HRASGTPase HRas isoform X1. (189 aa)
CD81Tetraspanin. (339 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (192 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa)
VAV3Guanine nucleotide exchange factor VAV3 isoform X1. (875 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1333 aa)
NFKBIENF-kappa-B inhibitor epsilon. (361 aa)
CD79AB-cell antigen receptor complex-associated protein alpha chain isoform X2. (237 aa)
BLNKB-cell linker protein isoform X1. (455 aa)
PIK3AP1Phosphoinositide 3-kinase adapter protein 1. (835 aa)
MALT1Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1. (850 aa)
SYKTyrosine-protein kinase. (635 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1333 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform X1. (878 aa)
LOC101370467Uncharacterized protein LOC101370467. (276 aa)
NFATC1Nuclear factor of activated T-cells, cytoplasmic 1. (823 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa)
BCL10B-cell lymphoma/leukemia 10 isoform X1. (233 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
PPP3R2Calcineurin subunit B type 2. (170 aa)
LYNTyrosine-protein kinase. (512 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
NFATC2Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (920 aa)
JUNTranscription factor AP-1 isoform X1; Belongs to the bZIP family. (335 aa)
LOC101367134GTPase HRas-like. (177 aa)
CR2Complement receptor type 2. (1094 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
LOC101372843Leukocyte immunoglobulin-like receptor subfamily A member 6. (438 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
CD22B-cell receptor CD22 isoform X1. (850 aa)
LOC101366544LOW QUALITY PROTEIN: ras-related C3 botulinum toxin substrate 1-like. (145 aa)
VAV1Proto-oncogene vav isoform X1. (864 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
NFKBIBNF-kappa-B inhibitor beta isoform X1. (359 aa)
CD19B-lymphocyte antigen CD19 isoform X1. (561 aa)
CD72B-cell differentiation antigen CD72. (364 aa)
NRASGTPase NRas. (189 aa)
PPP3CCSerine/threonine-protein phosphatase. (534 aa)
CD79BB-cell antigen receptor complex-associated protein beta chain. (222 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
IKBKGNF-kappa-B essential modulator isoform X1. (457 aa)
LOC101373702LOW QUALITY PROTEIN: leukocyte immunoglobulin-like receptor subfamily A member 6. (572 aa)
BTKTyrosine-protein kinase. (687 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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