STRINGSTRING
GNAI1 GNAI1 PLCB3 PLCB3 GNGT1 GNGT1 GRIN2C GRIN2C GRIA2 GRIA2 GUCY1A3 GUCY1A3 CALM1 CALM1 RPS6KA5 RPS6KA5 KCNJ3 KCNJ3 ADCY3 ADCY3 GNGT2 GNGT2 CACNA1G CACNA1G GNG7 GNG7 RYR1 RYR1 GNB5 GNB5 NOS1 NOS1 GNAQ GNAQ GNG10 GNG10 MAPK3 MAPK3 CACNA1I CACNA1I GNB4 GNB4 PRKCB PRKCB PRKACA PRKACA LOC101368814 LOC101368814 GNB2 GNB2 GNAI2 GNAI2 FOS FOS LOC101379027 LOC101379027 GRIA3 GRIA3 PLCB2 PLCB2 MAPK1 MAPK1 CALM3 CALM3 GNG8 GNG8 LOC101373722 LOC101373722 GRIN2A GRIN2A LOC101372085 LOC101372085 CAMK2A CAMK2A GNG13 GNG13 CACNA1H CACNA1H ADCY9 ADCY9 CALM2 CALM2 LOC101365806 LOC101365806 RASD1 RASD1 CREB1 CREB1 CAMK2D CAMK2D CACNA1C CACNA1C GNAI3 GNAI3 PRKG2 PRKG2 GNB1 GNB1 CALML6 CALML6 KCNJ9 KCNJ9 MTNR1A MTNR1A GNG2 GNG2 RYR3 RYR3 PRKCG PRKCG GRIA1 GRIA1 ADCY8 ADCY8 PER2 PER2 GRIN2B GRIN2B ADCYAP1 ADCYAP1 RYR2 RYR2 CACNA1D CACNA1D CALML3 CALML3 KCNJ5 KCNJ5 CALML4 CALML4 GRIA4 GRIA4 PRKACB PRKACB GNG5 GNG5 GNG3 GNG3 GNG4 GNG4 GNAS GNAS LOC105757053 LOC105757053 CAMK2B CAMK2B GNB3 GNB3 KCNJ6 KCNJ6 GUCY1A2 GUCY1A2 PLCB1 PLCB1 GRIN2D GRIN2D GNG12 GNG12 ADCY2 ADCY2 PRKCA PRKCA LOC101368222 LOC101368222 GRIN1 GRIN1 GNG11 GNG11 GUCY1B3 GUCY1B3 ADCY5 ADCY5 PER1 PER1 ITPR1 ITPR1 LOC101365290 LOC101365290 ADCY6 ADCY6 ADCY4 ADCY4 LOC101386691 LOC101386691 ADCY10 ADCY10 ADCY7 ADCY7 ITPR3 ITPR3 ADCY1 ADCY1 PER3 PER3 MTNR1B MTNR1B CALML5 CALML5 ADCYAP1R1 ADCYAP1R1 PLCB4 PLCB4 LOC101363792 LOC101363792
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (359 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (94 aa)
GRIN2CGlutamate receptor ionotropic, NMDA 2C. (1226 aa)
GRIA2Glutamate receptor 2 isoform X1. (940 aa)
GUCY1A3Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
CALM1Calmodulin isoform X1; Belongs to the calmodulin family. (155 aa)
RPS6KA5Ribosomal protein S6 kinase. (798 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2379 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
RYR1Ryanodine receptor 1. (4986 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5 isoform X1. (395 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1433 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2143 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC101368814Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X1. (340 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (436 aa)
FOSProto-oncogene c-Fos isoform X1. (380 aa)
LOC101379027Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GRIA3Glutamate receptor 3 isoform X2. (894 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
CALM3Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC101373722Calmodulin-alpha-like; Belongs to the calmodulin family. (149 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
LOC101372085calmodulin-A-like; Belongs to the calmodulin family. (271 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
CACNA1HVoltage-dependent T-type calcium channel subunit alpha-1H. (2347 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
CALM2Calmodulin isoform X1; Belongs to the calmodulin family. (155 aa)
LOC101365806Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform X1. (676 aa)
RASD1Dexamethasone-induced Ras-related protein 1. (279 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta. (477 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2190 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform X1. (340 aa)
CALML6Calmodulin-like protein 6. (167 aa)
KCNJ9G protein-activated inward rectifier potassium channel 3. (392 aa)
MTNR1AMelatonin receptor type 1A; Belongs to the G-protein coupled receptor 1 family. (364 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
RYR3Ryanodine receptor 3. (4846 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
GRIA1LOW QUALITY PROTEIN: glutamate receptor 1. (906 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
PER2Period circadian protein homolog 2. (1265 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1484 aa)
ADCYAP1Pituitary adenylate cyclase-activating polypeptide. (176 aa)
RYR2Ryanodine receptor 2. (3417 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
CALML3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
KCNJ5G protein-activated inward rectifier potassium channel 4. (413 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
GRIA4Glutamate receptor 4 isoform X2. (902 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1015 aa)
LOC105757053Neuroendocrine secretory protein 55. (246 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (542 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
KCNJ6G protein-activated inward rectifier potassium channel 2. (423 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (723 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
GRIN2DGlutamate receptor ionotropic, NMDA 2D. (1130 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
LOC101368222Ryanodine receptor 2-like. (1481 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (943 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GUCY1B3Guanylate cyclase soluble subunit beta-1 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (643 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
PER1Period circadian protein homolog 1. (1287 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2758 aa)
LOC101365290Guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (707 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
LOC101386691Calmodulin-like; Belongs to the calmodulin family. (176 aa)
ADCY10Adenylate cyclase type 10 isoform X1. (1623 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3 isoform X1. (2674 aa)
ADCY1Adenylate cyclase type 1. (907 aa)
PER3LOW QUALITY PROTEIN: period circadian protein homolog 3. (896 aa)
MTNR1BMelatonin receptor type 1B; Belongs to the G-protein coupled receptor 1 family. (357 aa)
CALML5Calmodulin-like protein 5. (149 aa)
ADCYAP1R1Pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (497 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
LOC101363792Adenylate cyclase type 10-like. (1182 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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