STRINGSTRING
PPP3CA PPP3CA PPP1CA PPP1CA PLCB3 PLCB3 GRIN2C GRIN2C GRIA2 GRIA2 CALM1 CALM1 RPS6KA1 RPS6KA1 PPP1CB PPP1CB MAP2K2 MAP2K2 PPP1CC PPP1CC ARAF ARAF GNAQ GNAQ MAPK3 MAPK3 EP300 EP300 ATF4 ATF4 PPP3R1 PPP3R1 PRKCB PRKCB PRKACA PRKACA PLCB2 PLCB2 MAPK1 MAPK1 CALM3 CALM3 LOC101373722 LOC101373722 GRIN2A GRIN2A CAMK4 CAMK4 RAP1A RAP1A RPS6KA3 RPS6KA3 LOC101372085 LOC101372085 CAMK2A CAMK2A CREBBP CREBBP CALM2 CALM2 HRAS HRAS RAP1B RAP1B CAMK2D CAMK2D CACNA1C CACNA1C CALML6 CALML6 PRKCG PRKCG GRIA1 GRIA1 ADCY8 ADCY8 LOC101372426 LOC101372426 GRIN2B GRIN2B CALML3 CALML3 CALML4 CALML4 PRKACB PRKACB RPS6KA6 RPS6KA6 CAMK2B CAMK2B PPP3R2 PPP3R2 MAP2K1 MAP2K1 PLCB1 PLCB1 GRIN2D GRIN2D LOC101367134 LOC101367134 PRKCA PRKCA ITPR2 ITPR2 GRIN1 GRIN1 RAF1 RAF1 RAPGEF3 RAPGEF3 ITPR1 ITPR1 NRAS NRAS PPP3CC PPP3CC RPS6KA2 RPS6KA2 LOC101386691 LOC101386691 PPP3CB PPP3CB ITPR3 ITPR3 ADCY1 ADCY1 CALML5 CALML5 BRAF BRAF PLCB4 PLCB4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP3CASerine/threonine-protein phosphatase. (521 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
GRIN2CGlutamate receptor ionotropic, NMDA 2C. (1226 aa)
GRIA2Glutamate receptor 2 isoform X1. (940 aa)
CALM1Calmodulin isoform X1; Belongs to the calmodulin family. (155 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
ARAFSerine/threonine-protein kinase A-Raf. (606 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
EP300Histone acetyltransferase p300. (2421 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
PPP3R1Calcineurin subunit B type 1 isoform X1. (170 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
CALM3Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
LOC101373722Calmodulin-alpha-like; Belongs to the calmodulin family. (149 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
CAMK4Calcium/calmodulin-dependent protein kinase type IV; Belongs to the protein kinase superfamily. (470 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
LOC101372085calmodulin-A-like; Belongs to the calmodulin family. (271 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa)
CREBBPCREB-binding protein isoform X1. (2433 aa)
CALM2Calmodulin isoform X1; Belongs to the calmodulin family. (155 aa)
HRASGTPase HRas isoform X1. (189 aa)
RAP1BRas-related protein Rap-1b isoform X1. (184 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta. (477 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2190 aa)
CALML6Calmodulin-like protein 6. (167 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
GRIA1LOW QUALITY PROTEIN: glutamate receptor 1. (906 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
LOC101372426Metabotropic glutamate receptor 5. (979 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1484 aa)
CALML3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa)
RPS6KA6Ribosomal protein S6 kinase. (744 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (542 aa)
PPP3R2Calcineurin subunit B type 2. (170 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
GRIN2DGlutamate receptor ionotropic, NMDA 2D. (1130 aa)
LOC101367134GTPase HRas-like. (177 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2639 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (943 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3 isoform X1. (923 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2758 aa)
NRASGTPase NRas. (189 aa)
PPP3CCSerine/threonine-protein phosphatase. (534 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
LOC101386691Calmodulin-like; Belongs to the calmodulin family. (176 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3 isoform X1. (2674 aa)
ADCY1Adenylate cyclase type 1. (907 aa)
CALML5Calmodulin-like protein 5. (149 aa)
BRAFSerine/threonine-protein kinase B-raf. (772 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.