76 items (Odobenus rosmarus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GABRA1	Gamma-aminobutyric acid receptor subunit alpha-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
	GABRA6	Gamma-aminobutyric acid receptor subunit alpha-6; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
	GABBR2	Gamma-aminobutyric acid type B receptor subunit 2. (941 aa)
	PDE1A	Phosphodiesterase. (531 aa)
	GNAT3	Guanine nucleotide-binding protein G(T) subunit alpha-3. (354 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
	HTR1D	5-hydroxytryptamine receptor 1D. (377 aa)
	LOC101383260	Taste receptor type 2. (304 aa)
	GABRA2	Gamma-aminobutyric acid receptor subunit alpha-2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (473 aa)
	GABRA4	Gamma-aminobutyric acid receptor subunit alpha-4 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (555 aa)
	P2RY4	P2Y purinoceptor 4; Belongs to the G-protein coupled receptor 1 family. (365 aa)
	SCN2A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2006 aa)
	SCN9A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1987 aa)
	SCN3A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2011 aa)
	SCNN1G	Amiloride-sensitive sodium channel subunit gamma; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (646 aa)
	SCNN1B	Amiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (641 aa)
	CACNA1A	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2501 aa)
	PRKACA	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
	CALHM1	Calcium homeostasis modulator protein 1. (344 aa)
	HTR1A	5-hydroxytryptamine receptor 1A. (422 aa)
	GNG13	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
	P2RY1	P2Y purinoceptor 1; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	PDE1B	Phosphodiesterase. (496 aa)
	LOC101381387	LOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 3E; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (455 aa)
	LOC101364710	5-hydroxytryptamine receptor 3C; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
	CACNA1C	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2190 aa)
	GRM4	Metabotropic glutamate receptor 4 isoform X1. (912 aa)
	P2RX3	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
	ADCY8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
	LOC101383512	Taste receptor type 2. (312 aa)
	LOC101384654	Taste receptor type 2. (322 aa)
	KCNK5	Potassium channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (499 aa)
	HTR1E	5-hydroxytryptamine receptor 1E. (365 aa)
	GABBR1	Gamma-aminobutyric acid type B receptor subunit 1 isoform X1. (963 aa)
	GABRA3	Gamma-aminobutyric acid receptor subunit alpha-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (520 aa)
	ENTPD2	Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (495 aa)
	CHRM3	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa)
	HTR1F	5-hydroxytryptamine receptor 1F. (366 aa)
	GNB3	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
	PDE1C	Phosphodiesterase. (769 aa)
	HTR3A	5-hydroxytryptamine receptor 3A isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (483 aa)
	HCN4	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4. (1197 aa)
	ASIC2	Acid-sensing ion channel 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (565 aa)
	HTR1B	5-hydroxytryptamine receptor 1B. (389 aa)
	LOC101367331	LOW QUALITY PROTEIN: taste receptor type 1 member 2. (937 aa)
	ADCY6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
	PKD2L1	Polycystic kidney disease 2-like 1 protein isoform X1. (811 aa)
	ADCY4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
	TRPM5	Transient receptor potential cation channel subfamily M member 5. (1150 aa)
	LOC105757628	LOW QUALITY PROTEIN: taste receptor type 2 member 16; Belongs to the G-protein coupled receptor T2R family. (250 aa)
	GABRA5	Gamma-aminobutyric acid receptor subunit alpha-5 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (521 aa)
	LOC101364414	LOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 3C-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
	LOC101372597	LOW QUALITY PROTEIN: taste receptor type 1 member 3. (897 aa)
	LOC101364118	LOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 3C-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3 isoform X1. (2674 aa)
	PKD1L3	LOW QUALITY PROTEIN: polycystic kidney disease protein 1-like 3. (1713 aa)
	LOC101383804	Taste receptor type 2. (309 aa)
	LOC101367291	Taste receptor type 2. (309 aa)
	LOC101384368	Taste receptor type 2. (311 aa)
	LOC101381309	LOW QUALITY PROTEIN: taste receptor type 1 member 1. (973 aa)
	LOC101367585	Taste receptor type 2. (352 aa)
	SCNN1A	Amiloride-sensitive sodium channel subunit alpha; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (687 aa)
	LOC101385964	Taste receptor type 2. (299 aa)
	LOC101366270	Taste receptor type 2. (309 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
	LOC101374949	Taste receptor type 2. (296 aa)
	LOC101382978	Taste receptor type 2. (294 aa)
	LOC101383835	Taste receptor type 2. (319 aa)
	LOC101366849	LOW QUALITY PROTEIN: taste receptor type 2 member 60; Belongs to the G-protein coupled receptor T2R family. (416 aa)
	LOC101383062	Taste receptor type 2. (297 aa)
	LOC101383544	Taste receptor type 2. (298 aa)
	HTR3B	5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (483 aa)
	LOC101381450	Taste receptor type 2. (264 aa)

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY4	ADCY6	A0A2U3ZII4	A0A2U3ZH57	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.972
ADCY4	ADCY8	A0A2U3ZII4	A0A2U3WLQ4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.953
ADCY4	ENTPD2	A0A2U3ZII4	A0A2U3WUA3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family.	0.905
ADCY4	GNAT3	A0A2U3ZII4	A0A2U3VG13	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(T) subunit alpha-3.	0.565
ADCY4	GNB3	A0A2U3ZII4	A0A2U3WX02	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3.	0.826
ADCY4	GNG13	A0A2U3ZII4	A0A2U3W4X2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13.	0.825
ADCY4	PDE1A	A0A2U3ZII4	A0A2U3VCW9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.677
ADCY4	PDE1B	A0A2U3ZII4	A0A2U3WCV1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.677
ADCY4	PDE1C	A0A2U3ZII4	A0A2U3WZC8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.677
ADCY4	PLCB3	A0A2U3ZII4	A0A2U3VH19	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.478
ADCY4	PRKACA	A0A2U3ZII4	A0A2U3VUI0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.	0.939
ADCY4	PRKACB	A0A2U3ZII4	A0A2U3WVN1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily.	0.939
ADCY6	ADCY4	A0A2U3ZH57	A0A2U3ZII4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.972
ADCY6	ADCY8	A0A2U3ZH57	A0A2U3WLQ4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.950
ADCY6	ENTPD2	A0A2U3ZH57	A0A2U3WUA3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family.	0.901
ADCY6	GNAT3	A0A2U3ZH57	A0A2U3VG13	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(T) subunit alpha-3.	0.565
ADCY6	GNB3	A0A2U3ZH57	A0A2U3WX02	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3.	0.826
ADCY6	GNG13	A0A2U3ZH57	A0A2U3W4X2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13.	0.823
ADCY6	PDE1A	A0A2U3ZH57	A0A2U3VCW9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.679
ADCY6	PDE1B	A0A2U3ZH57	A0A2U3WCV1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.926