STRINGSTRING
GABRA1 GABRA1 GABRA6 GABRA6 GABBR2 GABBR2 PDE1A PDE1A GNAT3 GNAT3 PLCB3 PLCB3 HTR1D HTR1D LOC101383260 LOC101383260 GABRA2 GABRA2 GABRA4 GABRA4 P2RY4 P2RY4 SCN2A SCN2A SCN9A SCN9A SCN3A SCN3A SCNN1G SCNN1G SCNN1B SCNN1B CACNA1A CACNA1A PRKACA PRKACA PLCB2 PLCB2 CALHM1 CALHM1 HTR1A HTR1A GNG13 GNG13 P2RY1 P2RY1 PDE1B PDE1B LOC101381387 LOC101381387 LOC101364710 LOC101364710 CACNA1C CACNA1C GRM4 GRM4 P2RX3 P2RX3 ADCY8 ADCY8 LOC101383512 LOC101383512 LOC101384654 LOC101384654 KCNK5 KCNK5 HTR1E HTR1E GABBR1 GABBR1 GABRA3 GABRA3 ENTPD2 ENTPD2 CHRM3 CHRM3 PRKACB PRKACB HTR1F HTR1F GNB3 GNB3 PLCB1 PLCB1 PDE1C PDE1C HTR3A HTR3A HCN4 HCN4 ASIC2 ASIC2 HTR1B HTR1B LOC101367331 LOC101367331 ADCY6 ADCY6 PKD2L1 PKD2L1 ADCY4 ADCY4 TRPM5 TRPM5 LOC105757628 LOC105757628 GABRA5 GABRA5 LOC101364414 LOC101364414 LOC101372597 LOC101372597 LOC101364118 LOC101364118 ITPR3 ITPR3 PKD1L3 PKD1L3 LOC101383804 LOC101383804 LOC101367291 LOC101367291 LOC101384368 LOC101384368 LOC101381309 LOC101381309 LOC101367585 LOC101367585 SCNN1A SCNN1A LOC101385964 LOC101385964 LOC101366270 LOC101366270 PLCB4 PLCB4 LOC101374949 LOC101374949 LOC101382978 LOC101382978 LOC101383835 LOC101383835 LOC101366849 LOC101366849 LOC101383062 LOC101383062 LOC101383544 LOC101383544 HTR3B HTR3B LOC101381450 LOC101381450
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GABRA1Gamma-aminobutyric acid receptor subunit alpha-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
GABRA6Gamma-aminobutyric acid receptor subunit alpha-6; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (941 aa)
PDE1APhosphodiesterase. (531 aa)
GNAT3Guanine nucleotide-binding protein G(T) subunit alpha-3. (354 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
HTR1D5-hydroxytryptamine receptor 1D. (377 aa)
LOC101383260Taste receptor type 2. (304 aa)
GABRA2Gamma-aminobutyric acid receptor subunit alpha-2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (473 aa)
GABRA4Gamma-aminobutyric acid receptor subunit alpha-4 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (555 aa)
P2RY4P2Y purinoceptor 4; Belongs to the G-protein coupled receptor 1 family. (365 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2006 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1987 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2011 aa)
SCNN1GAmiloride-sensitive sodium channel subunit gamma; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (646 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (641 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2501 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
CALHM1Calcium homeostasis modulator protein 1. (344 aa)
HTR1A5-hydroxytryptamine receptor 1A. (422 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
P2RY1P2Y purinoceptor 1; Belongs to the G-protein coupled receptor 1 family. (374 aa)
PDE1BPhosphodiesterase. (496 aa)
LOC101381387LOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 3E; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (455 aa)
LOC1013647105-hydroxytryptamine receptor 3C; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2190 aa)
GRM4Metabotropic glutamate receptor 4 isoform X1. (912 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
LOC101383512Taste receptor type 2. (312 aa)
LOC101384654Taste receptor type 2. (322 aa)
KCNK5Potassium channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (499 aa)
HTR1E5-hydroxytryptamine receptor 1E. (365 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1 isoform X1. (963 aa)
GABRA3Gamma-aminobutyric acid receptor subunit alpha-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (520 aa)
ENTPD2Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (495 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa)
HTR1F5-hydroxytryptamine receptor 1F. (366 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PDE1CPhosphodiesterase. (769 aa)
HTR3A5-hydroxytryptamine receptor 3A isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (483 aa)
HCN4Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4. (1197 aa)
ASIC2Acid-sensing ion channel 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (565 aa)
HTR1B5-hydroxytryptamine receptor 1B. (389 aa)
LOC101367331LOW QUALITY PROTEIN: taste receptor type 1 member 2. (937 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
PKD2L1Polycystic kidney disease 2-like 1 protein isoform X1. (811 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
TRPM5Transient receptor potential cation channel subfamily M member 5. (1150 aa)
LOC105757628LOW QUALITY PROTEIN: taste receptor type 2 member 16; Belongs to the G-protein coupled receptor T2R family. (250 aa)
GABRA5Gamma-aminobutyric acid receptor subunit alpha-5 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (521 aa)
LOC101364414LOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 3C-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
LOC101372597LOW QUALITY PROTEIN: taste receptor type 1 member 3. (897 aa)
LOC101364118LOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 3C-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3 isoform X1. (2674 aa)
PKD1L3LOW QUALITY PROTEIN: polycystic kidney disease protein 1-like 3. (1713 aa)
LOC101383804Taste receptor type 2. (309 aa)
LOC101367291Taste receptor type 2. (309 aa)
LOC101384368Taste receptor type 2. (311 aa)
LOC101381309LOW QUALITY PROTEIN: taste receptor type 1 member 1. (973 aa)
LOC101367585Taste receptor type 2. (352 aa)
SCNN1AAmiloride-sensitive sodium channel subunit alpha; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (687 aa)
LOC101385964Taste receptor type 2. (299 aa)
LOC101366270Taste receptor type 2. (309 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
LOC101374949Taste receptor type 2. (296 aa)
LOC101382978Taste receptor type 2. (294 aa)
LOC101383835Taste receptor type 2. (319 aa)
LOC101366849LOW QUALITY PROTEIN: taste receptor type 2 member 60; Belongs to the G-protein coupled receptor T2R family. (416 aa)
LOC101383062Taste receptor type 2. (297 aa)
LOC101383544Taste receptor type 2. (298 aa)
HTR3B5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (483 aa)
LOC101381450Taste receptor type 2. (264 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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