48 items (Odobenus rosmarus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HSD17B2	Estradiol 17-beta-dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (380 aa)
	STAR	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
	ADCY3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
	SCARB1	Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (509 aa)
	LOC101383271	Aromatase isoform X1; Belongs to the cytochrome P450 family. (503 aa)
	PRKACA	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
	LDLR	Low-density lipoprotein receptor. (926 aa)
	ACOT4	Acyl-coenzyme A thioesterase 4. (420 aa)
	LOC101365289	Acyl-coenzyme A thioesterase 1. (452 aa)
	PLA2G4E	Phospholipase A2. (864 aa)
	PLA2G4F	Phospholipase A2. (875 aa)
	PLA2G4D	Phospholipase A2. (817 aa)
	LOC101384623	Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family. (508 aa)
	ADCY9	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
	LHCGR	Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (695 aa)
	FSHR	Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (692 aa)
	HSD17B7	3-keto-steroid reductase isoform X1. (334 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	BMP6	Bone morphogenetic protein 6. (505 aa)
	PTGS2	Prostaglandin G/H synthase 2. (604 aa)
	LOC101382250	Cytochrome P450 1A1; Belongs to the cytochrome P450 family. (517 aa)
	LOC101384815	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
	ALOX5	Arachidonate 5-lipoxygenase isoform X1. (674 aa)
	ADCY8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
	LOC101365942	Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (543 aa)
	HSD17B1	Estradiol 17-beta-dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa)
	LOC101382939	Cytochrome P450 2J2; Belongs to the cytochrome P450 family. (502 aa)
	CGA	Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
	INSR	Tyrosine-protein kinase receptor. (1381 aa)
	LOC101369871	Follitropin subunit beta. (129 aa)
	IGF1	Insulin-like growth factor I isoform X1. (187 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa)
	GNAS	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1015 aa)
	LOC105757053	Neuroendocrine secretory protein 55. (246 aa)
	LOC101369994	Lutropin subunit beta. (141 aa)
	ADCY2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
	LOC101378904	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; Belongs to the 3-beta-HSD family. (373 aa)
	BMP15	Bone morphogenetic protein 15 isoform X1. (402 aa)
	ADCY5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
	PLA2G4B	Phospholipase A2. (782 aa)
	ADCY6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
	ADCY4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
	PLA2G4A	Phospholipase A2. (749 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1304 aa)
	ADCY7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
	ADCY1	Adenylate cyclase type 1. (907 aa)
	LOC101379669	Aldo-keto reductase family 1 member C1 homolog. (324 aa)
	LOC101377633	Aldo-keto reductase family 1 member C3-like. (262 aa)

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACOT4	LOC101365289	A0A2U3VVK1	A0A2U3VVK7	Acyl-coenzyme A thioesterase 4.	Acyl-coenzyme A thioesterase 1.	0.901
ADCY1	ADCY2	A0A2U3ZPU3	A0A2U3X0C6	Adenylate cyclase type 1.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.540
ADCY1	ADCY3	A0A2U3ZPU3	A0A2U3VJB8	Adenylate cyclase type 1.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.947
ADCY1	ADCY4	A0A2U3ZPU3	A0A2U3ZII4	Adenylate cyclase type 1.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.525
ADCY1	ADCY5	A0A2U3ZPU3	A0A2U3ZBK5	Adenylate cyclase type 1.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.500
ADCY1	ADCY6	A0A2U3ZPU3	A0A2U3ZH57	Adenylate cyclase type 1.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.502
ADCY1	ADCY7	A0A2U3ZPU3	A0A2U3ZP39	Adenylate cyclase type 1.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.632
ADCY1	ADCY8	A0A2U3ZPU3	A0A2U3WLQ4	Adenylate cyclase type 1.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.952
ADCY1	ADCY9	A0A2U3ZPU3	A0A2U3W5C3	Adenylate cyclase type 1.	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.630
ADCY1	GNAS	A0A2U3ZPU3	A0A2U3WWU5	Adenylate cyclase type 1.	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1.	0.965
ADCY1	LOC105757053	A0A2U3ZPU3	A0A2U3WWV0	Adenylate cyclase type 1.	Neuroendocrine secretory protein 55.	0.901
ADCY1	PRKACA	A0A2U3ZPU3	A0A2U3VUI0	Adenylate cyclase type 1.	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.	0.926
ADCY1	PRKACB	A0A2U3ZPU3	A0A2U3WVN1	Adenylate cyclase type 1.	cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily.	0.929
ADCY2	ADCY1	A0A2U3X0C6	A0A2U3ZPU3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1.	0.540
ADCY2	ADCY4	A0A2U3X0C6	A0A2U3ZII4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.495
ADCY2	ADCY5	A0A2U3X0C6	A0A2U3ZBK5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.991
ADCY2	ADCY6	A0A2U3X0C6	A0A2U3ZH57	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.795
ADCY2	ADCY7	A0A2U3X0C6	A0A2U3ZP39	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.496
ADCY2	ADCY8	A0A2U3X0C6	A0A2U3WLQ4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.518
ADCY2	ADCY9	A0A2U3X0C6	A0A2U3W5C3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.647