STRINGSTRING
WNT11 WNT11 CREB3 CREB3 ASIP ASIP GNAI1 GNAI1 PLCB3 PLCB3 FZD1 FZD1 CALM1 CALM1 POMC POMC ADCY3 ADCY3 MAP2K2 MAP2K2 WNT7A WNT7A GNAQ GNAQ MAPK3 MAPK3 EP300 EP300 WNT8A WNT8A DVL2 DVL2 PRKCB PRKCB PRKACA PRKACA FZD9 FZD9 GNAI2 GNAI2 CREB3L1 CREB3L1 PLCB2 PLCB2 MAPK1 MAPK1 WNT10B WNT10B WNT1 WNT1 CALM3 CALM3 LOC101373722 LOC101373722 WNT2B WNT2B LOC101372085 LOC101372085 WNT8B WNT8B FZD6 FZD6 WNT10A WNT10A WNT6 WNT6 CAMK2A CAMK2A CREB3L4 CREB3L4 CREBBP CREBBP ADCY9 ADCY9 CALM2 CALM2 GSK3B GSK3B HRAS HRAS WNT16 WNT16 FZD5 FZD5 CREB1 CREB1 WNT5A WNT5A DVL3 DVL3 CAMK2D CAMK2D WNT5B WNT5B WNT9A WNT9A WNT3A WNT3A GNAI3 GNAI3 FZD2 FZD2 DVL1 DVL1 CALML6 CALML6 WNT2 WNT2 DCT DCT PRKCG PRKCG ADCY8 ADCY8 EDNRB EDNRB WNT3 WNT3 WNT9B WNT9B FZD3 FZD3 WNT4 WNT4 CALML3 CALML3 CALML4 CALML4 TYR TYR PRKACB PRKACB GNAS GNAS LOC105757053 LOC105757053 CAMK2B CAMK2B FZD4 FZD4 MAP2K1 MAP2K1 KITLG KITLG PLCB1 PLCB1 LOC101367134 LOC101367134 ADCY2 ADCY2 TCF7L1 TCF7L1 FZD10 FZD10 PRKCA PRKCA WNT7B WNT7B CREB3L2 CREB3L2 FZD8 FZD8 CTNNB1 CTNNB1 RAF1 RAF1 ADCY5 ADCY5 KIT KIT NRAS NRAS ADCY6 ADCY6 ADCY4 ADCY4 EDN1 EDN1 MITF MITF LOC101386691 LOC101386691 ADCY7 ADCY7 ADCY1 ADCY1 CALML5 CALML5 FZD7 FZD7 LEF1 LEF1 TCF7L2 TCF7L2 TYRP1 TYRP1 PLCB4 PLCB4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (352 aa)
ASIPAgouti-signaling protein. (132 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (359 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
FZD1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (648 aa)
CALM1Calmodulin isoform X1; Belongs to the calmodulin family. (155 aa)
POMCPro-opiomelanocortin. (258 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
EP300Histone acetyltransferase p300. (2421 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X1. (734 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (597 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (436 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
CALM3Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
LOC101373722Calmodulin-alpha-like; Belongs to the calmodulin family. (149 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
LOC101372085calmodulin-A-like; Belongs to the calmodulin family. (271 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
FZD6Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (393 aa)
CREBBPCREB-binding protein isoform X1. (2433 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
CALM2Calmodulin isoform X1; Belongs to the calmodulin family. (155 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
HRASGTPase HRas isoform X1. (189 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (590 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3 isoform X1. (716 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta. (477 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (693 aa)
CALML6Calmodulin-like protein 6. (167 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
DCTL-dopachrome tautomerase. (548 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
EDNRBEndothelin B receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (443 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
CALML3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
TYRTyrosinase. (530 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1015 aa)
LOC105757053Neuroendocrine secretory protein 55. (246 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (542 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC101367134GTPase HRas-like. (177 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
TCF7L1Transcription factor 7-like 1. (586 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (519 aa)
FZD8Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (689 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (982 aa)
NRASGTPase NRas. (189 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
EDN1Endothelin-1 isoform X1. (227 aa)
MITFMicrophthalmia-associated transcription factor isoform X1. (526 aa)
LOC101386691Calmodulin-like; Belongs to the calmodulin family. (176 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ADCY1Adenylate cyclase type 1. (907 aa)
CALML5Calmodulin-like protein 5. (149 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (413 aa)
TCF7L2Transcription factor 7-like 2 isoform X1. (621 aa)
TYRP15,6-dihydroxyindole-2-carboxylic acid oxidase. (537 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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