STRINGSTRING
MAPK10 MAPK10 ADIPOR1 ADIPOR1 AGRP AGRP RELA RELA CPT1A CPT1A POMC POMC STK11 STK11 ACSBG2 ACSBG2 AKT1 AKT1 CAMKK2 CAMKK2 AKT2 AKT2 PRKAB1 PRKAB1 G6PC2 G6PC2 NPY NPY LEP LEP PRKCQ PRKCQ SLC2A4 SLC2A4 LOC101378833 LOC101378833 NFKBIA NFKBIA ACSL4 ACSL4 IRS4 IRS4 AKT3 AKT3 PRKAG1 PRKAG1 NFKB1 NFKB1 CHUK CHUK PRKAG3 PRKAG3 PPARGC1A PPARGC1A SLC2A1 SLC2A1 ADIPOR2 ADIPOR2 ACSL3 ACSL3 JAK2 JAK2 NFKBIE NFKBIE ACSL6 ACSL6 RXRG RXRG PRKAG2 PRKAG2 PRKAA1 PRKAA1 IRS2 IRS2 CPT1B CPT1B IRS1 IRS1 CPT1C CPT1C PTPN11 PTPN11 STAT3 STAT3 G6PC G6PC MTOR MTOR MAPK9 MAPK9 TRAF2 TRAF2 ADIPOQ ADIPOQ TNFRSF1A TNFRSF1A PRKAA2 PRKAA2 TNF TNF IKBKB IKBKB PPARA PPARA ACACB ACACB SOCS3 SOCS3 PRKAB2 PRKAB2 LOC101363590 LOC101363590 NFKBIB NFKBIB PCK2 PCK2 ACSBG1 ACSBG1 G6PC3 G6PC3 LOC101374328 LOC101374328 MAPK8 MAPK8 TRADD TRADD TNFRSF1B TNFRSF1B RXRA RXRA LEPR LEPR ACSL5 ACSL5 CD36 CD36 ACSL1 ACSL1 IKBKG IKBKG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK10Mitogen-activated protein kinase. (464 aa)
ADIPOR1Adiponectin receptor protein 1. (375 aa)
AGRPAgouti-related protein. (132 aa)
RELATranscription factor p65. (539 aa)
CPT1ACarnitine O-palmitoyltransferase 1, liver isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family. (778 aa)
POMCPro-opiomelanocortin. (258 aa)
STK11Serine/threonine-protein kinase STK11; Belongs to the protein kinase superfamily. (439 aa)
ACSBG2LOW QUALITY PROTEIN: long-chain-fatty-acid--CoA ligase ACSBG2. (688 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
CAMKK2Calcium/calmodulin-dependent protein kinase kinase 2 isoform X1. (584 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PRKAB15'-AMP-activated protein kinase subunit beta-1. (270 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (356 aa)
NPYPro-neuropeptide Y. (97 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
SLC2A4Solute carrier family 2, facilitated glucose transporter member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (508 aa)
LOC101378833Insulin receptor substrate 2-like. (528 aa)
NFKBIANF-kappa-B inhibitor alpha. (314 aa)
ACSL4long-chain-fatty-acid--CoA ligase 4 isoform X1. (711 aa)
IRS4LOW QUALITY PROTEIN: insulin receptor substrate 4. (1307 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X1. (337 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3. (464 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (803 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
ADIPOR2Adiponectin receptor protein 2. (386 aa)
ACSL3long-chain-fatty-acid--CoA ligase 3. (719 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
NFKBIENF-kappa-B inhibitor epsilon. (361 aa)
ACSL6long-chain-fatty-acid--CoA ligase 6 isoform X1. (697 aa)
RXRGRetinoic acid receptor RXR-gamma isoform X1. (463 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2 isoform X1. (569 aa)
PRKAA1Non-specific serine/threonine protein kinase. (528 aa)
IRS2Insulin receptor substrate 2. (1327 aa)
CPT1BCarnitine O-palmitoyltransferase 1, muscle isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
IRS1Insulin receptor substrate 1. (1233 aa)
CPT1CCarnitine O-palmitoyltransferase 1, brain isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family. (803 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2559 aa)
MAPK9Mitogen-activated protein kinase. (427 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (503 aa)
ADIPOQAdiponectin isoform X1. (266 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (451 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (468 aa)
ACACBacetyl-CoA carboxylase 2. (2456 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
PRKAB25'-AMP-activated protein kinase subunit beta-2 isoform X1. (272 aa)
LOC101363590LOW QUALITY PROTEIN: long-chain-fatty-acid--CoA ligase ACSBG2-like. (784 aa)
NFKBIBNF-kappa-B inhibitor beta isoform X1. (359 aa)
PCK2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1. (668 aa)
ACSBG1long-chain-fatty-acid--CoA ligase ACSBG1. (782 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
LOC101374328Tyrosine-protein phosphatase non-receptor type 11-like. (581 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1. (324 aa)
TNFRSF1BTumor necrosis factor receptor superfamily member 1B. (462 aa)
RXRARetinoic acid receptor RXR-alpha isoform X1. (497 aa)
LEPRLeptin receptor isoform X1. (1166 aa)
ACSL5long-chain-fatty-acid--CoA ligase 5 isoform X1. (724 aa)
CD36Platelet glycoprotein 4 isoform X1; Belongs to the CD36 family. (472 aa)
ACSL1long-chain-fatty-acid--CoA ligase 1. (633 aa)
IKBKGNF-kappa-B essential modulator isoform X1. (457 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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