75 items (Odobenus rosmarus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	PPP3CA	Serine/threonine-protein phosphatase. (521 aa)
	PDE1A	Phosphodiesterase. (531 aa)
	CACNA1S	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
	REN	Renin; Belongs to the peptidase A1 family. (404 aa)
	ADORA1	Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
	GNAI1	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (359 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
	GUCY1A3	Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
	ADRB3	Beta-3 adrenergic receptor. (408 aa)
	CALM1	Calmodulin isoform X1; Belongs to the calmodulin family. (155 aa)
	CTSB	Cathepsin B; Belongs to the peptidase C1 family. (339 aa)
	ORAI1	LOW QUALITY PROTEIN: calcium release-activated calcium channel protein 1. (405 aa)
	CACNA1F	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1983 aa)
	GNAQ	Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
	PPP3R1	Calcineurin subunit B type 1 isoform X1. (170 aa)
	PRKACA	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
	GNAI2	Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (436 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
	CALM3	Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
	LOC101373722	Calmodulin-alpha-like; Belongs to the calmodulin family. (149 aa)
	LOC101372085	calmodulin-A-like; Belongs to the calmodulin family. (271 aa)
	ADRB2	Beta-2 adrenergic receptor. (418 aa)
	NPR1	Guanylate cyclase. (1080 aa)
	KCNMA1	Calcium-activated potassium channel subunit alpha-1 isoform X1. (1261 aa)
	CALM2	Calmodulin isoform X1; Belongs to the calmodulin family. (155 aa)
	EDNRA	Endothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	AGT	Angiotensinogen; Belongs to the serpin family. (477 aa)
	CREB1	Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
	KCNJ2	Inward rectifier potassium channel 2. (427 aa)
	LOC101377413	Angiotensin-converting enzyme. (1312 aa)
	LOC101382544	Angiotensin-converting enzyme. (772 aa)
	PDE1B	Phosphodiesterase. (496 aa)
	EDN2	Endothelin-2 isoform X1. (179 aa)
	CACNA1C	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2190 aa)
	GNAI3	Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
	PRKG2	cGMP-dependent protein kinase. (762 aa)
	CALML6	Calmodulin-like protein 6. (167 aa)
	LOC101384734	Calcium-activated chloride channel regulator 1. (913 aa)
	CLCA4	LOW QUALITY PROTEIN: calcium-activated chloride channel regulator 4. (917 aa)
	CLCA2	Calcium-activated chloride channel regulator 2. (943 aa)
	PTGER4	Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (489 aa)
	NPPA	Natriuretic peptides A. (152 aa)
	ADCYAP1	Pituitary adenylate cyclase-activating polypeptide. (176 aa)
	CACNA1D	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
	CALML3	Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
	CALML4	LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
	ADRB1	Beta-1 adrenergic receptor. (468 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa)
	AQP1	Aquaporin-1 isoform X1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
	GNAS	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1015 aa)
	LOC105757053	Neuroendocrine secretory protein 55. (246 aa)
	EDN3	Endothelin-3. (198 aa)
	GUCY1A2	Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (723 aa)
	PPP3R2	Calcineurin subunit B type 2. (170 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
	PDE1C	Phosphodiesterase. (769 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2639 aa)
	PTGER2	Prostaglandin E2 receptor EP2 subtype; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	GUCY1B3	Guanylate cyclase soluble subunit beta-1 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (643 aa)
	ADCY5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2758 aa)
	LOC101365290	Guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (707 aa)
	ADCY6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (534 aa)
	LOC105757534	Phosphodiesterase. (427 aa)
	EDN1	Endothelin-1 isoform X1. (227 aa)
	LOC101386691	Calmodulin-like; Belongs to the calmodulin family. (176 aa)
	AGTR1	Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (525 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3 isoform X1. (2674 aa)
	CALML5	Calmodulin-like protein 5. (149 aa)
	ADCYAP1R1	Pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (497 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
	PDE3B	Phosphodiesterase. (1112 aa)
	PDE3A	Phosphodiesterase. (791 aa)

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY5	ADCY6	A0A2U3ZBK5	A0A2U3ZH57	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.950
ADCY5	CALM1	A0A2U3ZBK5	A0A2U3VI45	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin isoform X1; Belongs to the calmodulin family.	0.743
ADCY5	CALM2	A0A2U3ZBK5	A0A2U3W5L9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin isoform X1; Belongs to the calmodulin family.	0.743
ADCY5	CALM3	A0A2U3ZBK5	A0A2U3VZL3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin isoform X2; Belongs to the calmodulin family.	0.743
ADCY5	CALML3	A0A2U3ZBK5	A0A2U3WRI4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin-like protein 3; Belongs to the calmodulin family.	0.743
ADCY5	CALML4	A0A2U3ZBK5	A0A2U3WSS0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	LOW QUALITY PROTEIN: calmodulin-like protein 4.	0.739
ADCY5	CALML5	A0A2U3ZBK5	A0A2U3ZS75	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin-like protein 5.	0.748
ADCY5	CALML6	A0A2U3ZBK5	A0A2U3WFQ9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin-like protein 6.	0.691
ADCY5	GNAI1	A0A2U3ZBK5	A0A2U3VGF2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1.	0.939
ADCY5	GNAI2	A0A2U3ZBK5	A0A2U3VV83	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1.	0.939
ADCY5	GNAI3	A0A2U3ZBK5	A0A2U3WF26	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(K) subunit alpha.	0.939
ADCY5	GNAS	A0A2U3ZBK5	A0A2U3WWU5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1.	0.998
ADCY5	LOC101372085	A0A2U3ZBK5	A0A2U3W124	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	calmodulin-A-like; Belongs to the calmodulin family.	0.743
ADCY5	LOC101373722	A0A2U3ZBK5	A0A2U3W067	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin-alpha-like; Belongs to the calmodulin family.	0.743
ADCY5	LOC101386691	A0A2U3ZBK5	A0A2U3ZKS3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin-like; Belongs to the calmodulin family.	0.697
ADCY5	LOC105757053	A0A2U3ZBK5	A0A2U3WWV0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Neuroendocrine secretory protein 55.	0.901
ADCY5	LOC105757534	A0A2U3ZBK5	A0A2U3ZIX3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.813
ADCY5	NPPA	A0A2U3ZBK5	A0A2U3WPW1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Natriuretic peptides A.	0.469
ADCY5	PDE1A	A0A2U3ZBK5	A0A2U3VCW9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.679
ADCY5	PDE1B	A0A2U3ZBK5	A0A2U3WCV1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.737