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ATP2B2 ATP2B2 ATP2B4 ATP2B4 PLCB3 PLCB3 GUCY1A3 GUCY1A3 ADRB3 ADRB3 CALM1 CALM1 SLC9A1 SLC9A1 ADCY3 ADCY3 NOS1 NOS1 GNAQ GNAQ ATP1B3 ATP1B3 LPO LPO ADRA1D ADRA1D VAMP2 VAMP2 ATP1B2 ATP1B2 PRKCB PRKCB PRKACA PRKACA BEST2 BEST2 CAMP CAMP PLCB2 PLCB2 LOC101375463 LOC101375463 AQP5 AQP5 CALM3 CALM3 LOC101373722 LOC101373722 LOC101372085 LOC101372085 ADRB2 ADRB2 ADCY9 ADCY9 KCNMA1 KCNMA1 CALM2 CALM2 ADRA1B ADRA1B CST3 CST3 LYZ LYZ ATP1B1 ATP1B1 PRKG2 PRKG2 CALML6 CALML6 ATP1A4 ATP1A4 ATP1A2 ATP1A2 ATP1A3 ATP1A3 KCNN4 KCNN4 SLC4A2 SLC4A2 RYR3 RYR3 PRKCG PRKCG ADCY8 ADCY8 CD38 CD38 BST1 BST1 CALML3 CALML3 CALML4 CALML4 ADRB1 ADRB1 ADRA1A ADRA1A CHRM3 CHRM3 SLC12A2 SLC12A2 PRKACB PRKACB GNAS GNAS LOC105757053 LOC105757053 AMY2B AMY2B GUCY1A2 GUCY1A2 TRPV6 TRPV6 PLCB1 PLCB1 ADCY2 ADCY2 PRKCA PRKCA ITPR2 ITPR2 ATP1A1 ATP1A1 LOC101384892 LOC101384892 GUCY1B3 GUCY1B3 ADCY5 ADCY5 ITPR1 ITPR1 LOC101365290 LOC101365290 ADCY6 ADCY6 ADCY4 ADCY4 LOC101365920 LOC101365920 DMBT1 DMBT1 LOC101386691 LOC101386691 MUC7 MUC7 ATP1B4 ATP1B4 ADCY7 ADCY7 ITPR3 ITPR3 ATP2B3 ATP2B3 ADCY1 ADCY1 CALML5 CALML5 PLCB4 PLCB4 ATP2B1 ATP2B1 FXYD2 FXYD2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1242 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
GUCY1A3Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
ADRB3Beta-3 adrenergic receptor. (408 aa)
CALM1Calmodulin isoform X1; Belongs to the calmodulin family. (155 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1433 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
LPOLactoperoxidase isoform X1. (712 aa)
ADRA1Dalpha-1D adrenergic receptor. (569 aa)
VAMP2Vesicle-associated membrane protein 2 isoform X1. (116 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
BEST2Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (508 aa)
CAMPCathelicidin antimicrobial peptide. (170 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
LOC101375463Lysozyme C, milk isozyme-like; Belongs to the glycosyl hydrolase 22 family. (148 aa)
AQP5Aquaporin-5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
CALM3Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
LOC101373722Calmodulin-alpha-like; Belongs to the calmodulin family. (149 aa)
LOC101372085calmodulin-A-like; Belongs to the calmodulin family. (271 aa)
ADRB2Beta-2 adrenergic receptor. (418 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
KCNMA1Calcium-activated potassium channel subunit alpha-1 isoform X1. (1261 aa)
CALM2Calmodulin isoform X1; Belongs to the calmodulin family. (155 aa)
ADRA1Balpha-1B adrenergic receptor. (518 aa)
CST3cystatin-C; Belongs to the cystatin family. (149 aa)
LYZLysozyme; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Belongs to the glycosyl hydrolase 22 family. (148 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
CALML6Calmodulin-like protein 6. (167 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1035 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
KCNN4Intermediate conductance calcium-activated potassium channel protein 4. (427 aa)
SLC4A2Anion exchange protein. (1237 aa)
RYR3Ryanodine receptor 3. (4846 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
CD38ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1. (305 aa)
BST1LOW QUALITY PROTEIN: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2. (312 aa)
CALML3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
ADRB1Beta-1 adrenergic receptor. (468 aa)
ADRA1Aalpha-1A adrenergic receptor. (465 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
SLC12A2Solute carrier family 12 member 2 isoform X1. (1205 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1015 aa)
LOC105757053Neuroendocrine secretory protein 55. (246 aa)
AMY2BAlpha-amylase. (511 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (723 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (724 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2639 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
LOC101384892Lysozyme-like protein 1; Belongs to the glycosyl hydrolase 22 family. (148 aa)
GUCY1B3Guanylate cyclase soluble subunit beta-1 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (643 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2758 aa)
LOC101365290Guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (707 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
LOC101365920LOW QUALITY PROTEIN: mucin-5B. (4745 aa)
DMBT1LOW QUALITY PROTEIN: deleted in malignant brain tumors 1 protein. (2345 aa)
LOC101386691Calmodulin-like; Belongs to the calmodulin family. (176 aa)
MUC7Mucin-7. (260 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (360 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3 isoform X1. (2674 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1256 aa)
ADCY1Adenylate cyclase type 1. (907 aa)
CALML5Calmodulin-like protein 5. (149 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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