STRINGSTRING
CA2 CA2 GNAI1 GNAI1 PLCB3 PLCB3 ACTB ACTB CALM1 CALM1 SLC9A1 SLC9A1 ADCY3 ADCY3 KCNK2 KCNK2 GNAQ GNAQ ATP1B3 ATP1B3 KCNK10 KCNK10 ATP1B2 ATP1B2 PRKCB PRKCB PRKACA PRKACA GNAI2 GNAI2 PLCB2 PLCB2 CALM3 CALM3 LOC101373722 LOC101373722 HRH2 HRH2 LOC101372085 LOC101372085 SSTR2 SSTR2 CAMK2A CAMK2A ADCY9 ADCY9 CALM2 CALM2 MYLK3 MYLK3 KCNQ1 KCNQ1 KCNJ16 KCNJ16 KCNJ2 KCNJ2 ATP1B1 ATP1B1 CAMK2D CAMK2D GNAI3 GNAI3 CALML6 CALML6 ATP1A4 ATP1A4 KCNJ10 KCNJ10 ATP1A2 ATP1A2 ATP1A3 ATP1A3 CFTR CFTR SLC4A2 SLC4A2 PRKCG PRKCG KCNE2 KCNE2 ADCY8 ADCY8 GAST GAST CALML3 CALML3 KCNJ1 KCNJ1 ATP4B ATP4B CALML4 CALML4 CHRM3 CHRM3 CCKBR CCKBR SST SST PRKACB PRKACB GNAS GNAS LOC105757053 LOC105757053 CAMK2B CAMK2B SLC26A7 SLC26A7 PLCB1 PLCB1 ADCY2 ADCY2 PRKCA PRKCA ITPR2 ITPR2 ATP1A1 ATP1A1 KCNJ15 KCNJ15 EZR EZR ATP4A ATP4A SLC9A4 SLC9A4 MYLK MYLK ADCY5 ADCY5 ITPR1 ITPR1 ADCY6 ADCY6 ADCY4 ADCY4 LOC101386691 LOC101386691 ATP1B4 ATP1B4 MYLK2 MYLK2 MYLK4 MYLK4 ADCY7 ADCY7 ITPR3 ITPR3 ADCY1 ADCY1 CALML5 CALML5 PLCB4 PLCB4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (359 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
ACTBActin, cytoplasmic 1 isoform X2. (375 aa)
CALM1Calmodulin isoform X1; Belongs to the calmodulin family. (155 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
KCNK2Potassium channel subfamily K member 2 isoform X1; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
KCNK10Potassium channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (538 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (436 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
CALM3Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
LOC101373722Calmodulin-alpha-like; Belongs to the calmodulin family. (149 aa)
HRH2Histamine H2 receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
LOC101372085calmodulin-A-like; Belongs to the calmodulin family. (271 aa)
SSTR2Somatostatin receptor type 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
CALM2Calmodulin isoform X1; Belongs to the calmodulin family. (155 aa)
MYLK3Myosin light chain kinase 3. (807 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (671 aa)
KCNJ16Inward rectifier potassium channel 16. (419 aa)
KCNJ2Inward rectifier potassium channel 2. (427 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta. (477 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
CALML6Calmodulin-like protein 6. (167 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1035 aa)
KCNJ10ATP-sensitive inward rectifier potassium channel 10. (379 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1483 aa)
SLC4A2Anion exchange protein. (1237 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
KCNE2Potassium voltage-gated channel subfamily E member 2. (123 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
GASTGastrin. (104 aa)
CALML3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
KCNJ1ATP-sensitive inward rectifier potassium channel 1 isoform X1. (391 aa)
ATP4BSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
CCKBRGastrin/cholecystokinin type B receptor; Belongs to the G-protein coupled receptor 1 family. (455 aa)
SSTSomatostatin. (116 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1015 aa)
LOC105757053Neuroendocrine secretory protein 55. (246 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (542 aa)
SLC26A7Anion exchange transporter. (656 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2639 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
KCNJ15ATP-sensitive inward rectifier potassium channel 15. (375 aa)
EZREzrin isoform X1. (584 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1034 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (797 aa)
MYLKMyosin light chain kinase, smooth muscle isoform X1. (1998 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2758 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
LOC101386691Calmodulin-like; Belongs to the calmodulin family. (176 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (360 aa)
MYLK2Myosin light chain kinase 2, skeletal/cardiac muscle isoform X1. (686 aa)
MYLK4Myosin light chain kinase family member 4. (681 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3 isoform X1. (2674 aa)
ADCY1Adenylate cyclase type 1. (907 aa)
CALML5Calmodulin-like protein 5. (149 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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