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ATP2B2 ATP2B2 ATP2B4 ATP2B4 SLC4A4 SLC4A4 CTRL CTRL CA2 CA2 TPCN2 TPCN2 PLCB3 PLCB3 RAC1 RAC1 SLC9A1 SLC9A1 ADCY3 ADCY3 PLA2G1B PLA2G1B GNAQ GNAQ LOC101371862 LOC101371862 PLA2G2D PLA2G2D ATP2A1 ATP2A1 PLA2G2F PLA2G2F PLA2G5 PLA2G5 TRPC1 TRPC1 ATP1B3 ATP1B3 CPA1 CPA1 CPA2 CPA2 ATP1B2 ATP1B2 PRKCB PRKCB RAB3D RAB3D RHOA RHOA PLA2G3 PLA2G3 PLCB2 PLCB2 RAP1A RAP1A CCKAR CCKAR ADCY9 ADCY9 KCNMA1 KCNMA1 SCT SCT KCNQ1 KCNQ1 RAB8A RAB8A SCTR SCTR CPA3 CPA3 CPB1 CPB1 RAB27B RAB27B RAP1B RAP1B ATP1B1 ATP1B1 PLA2G12B PLA2G12B ATP1A4 ATP1A4 ATP1A2 ATP1A2 ATP1A3 ATP1A3 CFTR CFTR CPB2 CPB2 SLC4A2 SLC4A2 LOC101377802 LOC101377802 LOC101384734 LOC101384734 CLCA4 CLCA4 CLCA2 CLCA2 PRKCG PRKCG ADCY8 ADCY8 CD38 CD38 BST1 BST1 RYR2 RYR2 PLA2G12A PLA2G12A CELA3B CELA3B SLC26A3 SLC26A3 CHRM3 CHRM3 CTRB1 CTRB1 LOC101367705 LOC101367705 SLC12A2 SLC12A2 PNLIPRP1 PNLIPRP1 GNAS GNAS PNLIPRP2 PNLIPRP2 LOC105757053 LOC105757053 AMY2B AMY2B RAB11A RAB11A PRSS2 PRSS2 PLCB1 PLCB1 ADCY2 ADCY2 PRKCA PRKCA ITPR2 ITPR2 ATP2A3 ATP2A3 ATP1A1 ATP1A1 LOC101368222 LOC101368222 LOC101378334 LOC101378334 LOC101367998 LOC101367998 LOC101366544 LOC101366544 ATP2A2 ATP2A2 ADCY5 ADCY5 PLA2G2C PLA2G2C ITPR1 ITPR1 ADCY6 ADCY6 CEL CEL ADCY4 ADCY4 ATP1B4 ATP1B4 ADCY7 ADCY7 ITPR3 ITPR3 ATP2B3 ATP2B3 ADCY1 ADCY1 PNLIP PNLIP PLCB4 PLCB4 ATP2B1 ATP2B1 FXYD2 FXYD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1242 aa)
SLC4A4Anion exchange protein. (1127 aa)
CTRLChymotrypsin-like protease CTRL-1; Belongs to the peptidase S1 family. (268 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
TPCN2Two pore calcium channel protein 2. (752 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
PLA2G1BPhospholipase A(2). (147 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
LOC101371862Phospholipase A(2). (142 aa)
PLA2G2DPhospholipase A(2). (145 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1000 aa)
PLA2G2FPhospholipase A(2). (210 aa)
PLA2G5Phospholipase A(2). (137 aa)
TRPC1Short transient receptor potential channel 1 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
CPA1Carboxypeptidase A1 isoform X1. (419 aa)
CPA2Carboxypeptidase A2. (417 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
RAB3DRas-related protein Rab-3D. (219 aa)
RHOATransforming protein RhoA isoform X1. (193 aa)
PLA2G3Group 3 secretory phospholipase A2. (522 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
CCKARCholecystokinin receptor type A; Belongs to the G-protein coupled receptor 1 family. (428 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
KCNMA1Calcium-activated potassium channel subunit alpha-1 isoform X1. (1261 aa)
SCTSecretin. (130 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (671 aa)
RAB8ARas-related protein Rab-8A. (207 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (449 aa)
CPA3Mast cell carboxypeptidase A isoform X1. (417 aa)
CPB1Carboxypeptidase B. (417 aa)
RAB27BRas-related protein Rab-27B. (218 aa)
RAP1BRas-related protein Rap-1b isoform X1. (184 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
PLA2G12BGroup XIIB secretory phospholipase A2-like protein isoform X1. (195 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1035 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1483 aa)
CPB2Carboxypeptidase B2. (423 aa)
SLC4A2Anion exchange protein. (1237 aa)
LOC101377802Phospholipase A(2). (168 aa)
LOC101384734Calcium-activated chloride channel regulator 1. (913 aa)
CLCA4LOW QUALITY PROTEIN: calcium-activated chloride channel regulator 4. (917 aa)
CLCA2Calcium-activated chloride channel regulator 2. (943 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
CD38ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1. (305 aa)
BST1LOW QUALITY PROTEIN: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2. (312 aa)
RYR2Ryanodine receptor 2. (3417 aa)
PLA2G12AGroup XIIA secretory phospholipase A2. (190 aa)
CELA3BChymotrypsin-like elastase family member 3B isoform X1; Belongs to the peptidase S1 family. (285 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (759 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
CTRB1Chymotrypsinogen B; Belongs to the peptidase S1 family. (263 aa)
LOC101367705Chymotrypsinogen B-like; Belongs to the peptidase S1 family. (297 aa)
SLC12A2Solute carrier family 12 member 2 isoform X1. (1205 aa)
PNLIPRP1Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (467 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1015 aa)
PNLIPRP2Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (469 aa)
LOC105757053Neuroendocrine secretory protein 55. (246 aa)
AMY2BAlpha-amylase. (511 aa)
RAB11ARas-related protein Rab-11A isoform X1. (216 aa)
PRSS2Trypsin-2; Belongs to the peptidase S1 family. (248 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2639 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (999 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
LOC101368222Ryanodine receptor 2-like. (1481 aa)
LOC101378334Cationic trypsin-like isoform X1; Belongs to the peptidase S1 family. (263 aa)
LOC101367998LOW QUALITY PROTEIN: chymotrypsinogen B; Belongs to the peptidase S1 family. (264 aa)
LOC101366544LOW QUALITY PROTEIN: ras-related C3 botulinum toxin substrate 1-like. (145 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1050 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
PLA2G2CPhospholipase A(2). (170 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2758 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (632 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (360 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3 isoform X1. (2674 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1256 aa)
ADCY1Adenylate cyclase type 1. (907 aa)
PNLIPTriacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (466 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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