48 items (Odobenus rosmarus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NCEH1	Neutral cholesterol ester hydrolase 1 isoform X1. (408 aa)
	LCAT	Phosphatidylcholine-sterol acyltransferase. (440 aa)
	STAR	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
	LDLRAP1	Low density lipoprotein receptor adapter protein 1. (309 aa)
	STARD3	stAR-related lipid transfer protein 3 isoform X1. (445 aa)
	SCARB1	Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (509 aa)
	LRPAP1	Alpha-2-macroglobulin receptor-associated protein. (362 aa)
	ABCB11	Bile salt export pump isoform X1. (1325 aa)
	LRP2	Low-density lipoprotein receptor-related protein 2. (4645 aa)
	TSPO	Translocator protein. (169 aa)
	LOC101367833	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa)
	LDLR	Low-density lipoprotein receptor. (926 aa)
	NPC2	Epididymal secretory protein E1. (185 aa)
	ABCG8	ATP-binding cassette sub-family G member 8. (670 aa)
	ABCG5	ATP-binding cassette sub-family G member 5. (652 aa)
	APOC2	Apolipoprotein C-II. (101 aa)
	APOE	Apolipoprotein E. (329 aa)
	LOC101374314	Sterol 26-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (535 aa)
	MYLIP	E3 ubiquitin-protein ligase MYLIP. (445 aa)
	PLTP	Phospholipid transfer protein. (444 aa)
	APOB	Apolipoprotein B-100. (4435 aa)
	APOH	Beta-2-glycoprotein 1. (345 aa)
	SOAT2	O-acyltransferase. (524 aa)
	VDAC2	Voltage-dependent anion-selective channel protein 2 isoform X1. (309 aa)
	ABCA1	ATP-binding cassette sub-family A member 1. (2206 aa)
	LIPG	Endothelial lipase. (503 aa)
	ANGPTL3	Angiopoietin-related protein 3. (460 aa)
	ANGPTL4	Angiopoietin-related protein 4 isoform X1. (412 aa)
	LIPA	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (399 aa)
	NPC1	LOW QUALITY PROTEIN: Niemann-Pick C1 protein. (1398 aa)
	VAPB	Vesicle-associated membrane protein-associated protein B/C. (243 aa)
	LOC101374369	Voltage-dependent anion-selective channel protein 3-like. (283 aa)
	APOA4	Apolipoprotein A-IV. (382 aa)
	APOC3	Apolipoprotein C-III. (100 aa)
	VAPA	Vesicle-associated membrane protein-associated protein A isoform X1. (294 aa)
	TSPO2	Translocator protein 2 isoform X1. (171 aa)
	LOC101362133	Angiopoietin-like protein 8. (198 aa)
	SOAT1	LOW QUALITY PROTEIN: sterol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family. (621 aa)
	LRP1	Prolow-density lipoprotein receptor-related protein 1 isoform X1. (4561 aa)
	VDAC1	Voltage-dependent anion-selective channel protein 1 isoform X1. (294 aa)
	SORT1	Sortilin. (868 aa)
	LIPC	Hepatic triacylglycerol lipase. (500 aa)
	CD36	Platelet glycoprotein 4 isoform X1; Belongs to the CD36 family. (472 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (479 aa)
	VDAC3	Voltage-dependent anion-selective channel protein 3 isoform X1. (289 aa)
	APOA2	Truncated apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism; Belongs to the apolipoprotein A2 family. (100 aa)
	APOA1	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (266 aa)
	APOC1	Truncated apolipoprotein C-I; Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the in [...] (88 aa)

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	APOA1	A0A2U3WLL8	P0DMS6	ATP-binding cassette sub-family A member 1.	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	0.993
ABCA1	APOA2	A0A2U3WLL8	P0DM94	ATP-binding cassette sub-family A member 1.	Truncated apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism; Belongs to the apolipoprotein A2 family.	0.455
ABCA1	APOA4	A0A2U3WLL8	A0A2U3X0L9	ATP-binding cassette sub-family A member 1.	Apolipoprotein A-IV.	0.542
ABCA1	APOB	A0A2U3WLL8	A0A2U3WB12	ATP-binding cassette sub-family A member 1.	Apolipoprotein B-100.	0.522
ABCA1	APOC3	A0A2U3WLL8	A0A2U3X0U6	ATP-binding cassette sub-family A member 1.	Apolipoprotein C-III.	0.405
ABCA1	APOE	A0A2U3WLL8	A0A2U3VZR7	ATP-binding cassette sub-family A member 1.	Apolipoprotein E.	0.629
ABCA1	CD36	A0A2U3WLL8	A0A2U3ZTY4	ATP-binding cassette sub-family A member 1.	Platelet glycoprotein 4 isoform X1; Belongs to the CD36 family.	0.454
ABCA1	LCAT	A0A2U3WLL8	A0A2U3VFD8	ATP-binding cassette sub-family A member 1.	Phosphatidylcholine-sterol acyltransferase.	0.460
ABCA1	LIPC	A0A2U3WLL8	A0A2U3ZNC0	ATP-binding cassette sub-family A member 1.	Hepatic triacylglycerol lipase.	0.456
ABCA1	LOC101367833	A0A2U3WLL8	A0A2U3VTZ3	ATP-binding cassette sub-family A member 1.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.456
ABCA1	LOC101374314	A0A2U3WLL8	A0A2U3W3X0	ATP-binding cassette sub-family A member 1.	Sterol 26-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family.	0.451
ABCA1	NPC1	A0A2U3WLL8	A0A2U3WW66	ATP-binding cassette sub-family A member 1.	LOW QUALITY PROTEIN: Niemann-Pick C1 protein.	0.461
ABCA1	SCARB1	A0A2U3WLL8	A0A2U3VLU9	ATP-binding cassette sub-family A member 1.	Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family.	0.624
ABCB11	ABCG5	A0A2U3VP90	A0A2U3VXN4	Bile salt export pump isoform X1.	ATP-binding cassette sub-family G member 5.	0.574
ABCB11	ABCG8	A0A2U3VP90	A0A2U3VXM0	Bile salt export pump isoform X1.	ATP-binding cassette sub-family G member 8.	0.543
ABCB11	LOC101367833	A0A2U3VP90	A0A2U3VTZ3	Bile salt export pump isoform X1.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.637
ABCB11	LOC101374314	A0A2U3VP90	A0A2U3W3X0	Bile salt export pump isoform X1.	Sterol 26-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family.	0.451
ABCB11	SCARB1	A0A2U3VP90	A0A2U3VLU9	Bile salt export pump isoform X1.	Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family.	0.440
ABCG5	ABCB11	A0A2U3VXN4	A0A2U3VP90	ATP-binding cassette sub-family G member 5.	Bile salt export pump isoform X1.	0.574
ABCG5	ABCG8	A0A2U3VXN4	A0A2U3VXM0	ATP-binding cassette sub-family G member 5.	ATP-binding cassette sub-family G member 8.	0.999