STRINGSTRING
RHOG RHOG HCLS1 HCLS1 CLTA CLTA DNM1 DNM1 ARPC4 ARPC4 CDH1 CDH1 ELMO3 ELMO3 ACTB ACTB RAC1 RAC1 ARPC1A ARPC1A ARPC1B ARPC1B WASF2 WASF2 SHC2 SHC2 ARPC3 ARPC3 SHC4 SHC4 PXN PXN SEPT1 SEPT1 PIK3CD PIK3CD PIK3CA PIK3CA RHOA RHOA CRKL CRKL PIK3R3 PIK3R3 FN1 FN1 CLTB CLTB ITGB1 ITGB1 ARPC2 ARPC2 SEPT12 SEPT12 CRK CRK PIK3R2 PIK3R2 ARHGAP10 ARHGAP10 ARHGEF26 ARHGEF26 ELMO2 ELMO2 PTK2 PTK2 ITGA5 ITGA5 SEPT11 SEPT11 WASF1 WASF1 VCL VCL GAB1 GAB1 SEPT8 SEPT8 CD2AP CD2AP MET MET CAV2 CAV2 CAV1 CAV1 SHC3 SHC3 MAD2L2 MAD2L2 CDC42 CDC42 DNM3 DNM3 CBL CBL SEPT2 SEPT2 CAV3 CAV3 BCAR1 BCAR1 PIK3CB PIK3CB ILK ILK LOC101381905 LOC101381905 CLTCL1 CLTCL1 PIK3R1 PIK3R1 CTNNB1 CTNNB1 ARPC5L ARPC5L LOC101366544 LOC101366544 SEPT9 SEPT9 ARPC5 ARPC5 LOC101381443 LOC101381443 CLTC CLTC CTNNA1 CTNNA1 LOC101365594 LOC101365594 DNM2 DNM2 LOC101366585 LOC101366585 LOC101375473 LOC101375473 SHC1 SHC1 DOCK1 DOCK1 WASL WASL SEPT6 SEPT6 SRC SRC CTNNA2 CTNNA2 ELMO1 ELMO1 CTTN CTTN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RHOGRho-related GTP-binding protein RhoG. (191 aa)
HCLS1Hematopoietic lineage cell-specific protein. (478 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
DNM1Dynamin-1 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (186 aa)
CDH1Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa)
ELMO3Engulfment and cell motility protein 3 isoform X1. (720 aa)
ACTBActin, cytoplasmic 1 isoform X2. (375 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
ARPC1BActin-related protein 2/3 complex subunit 1B. (344 aa)
WASF2wiskott-Aldrich syndrome protein family member 2. (498 aa)
SHC2SHC-transforming protein 2. (586 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
SHC4SHC-transforming protein 4. (630 aa)
PXNPaxillin; Belongs to the paxillin family. (557 aa)
SEPT1Septin-1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (367 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RHOATransforming protein RhoA isoform X1. (193 aa)
CRKLCrk-like protein. (303 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (507 aa)
FN1Fibronectin isoform X1. (2476 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
SEPT12Septin-12 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (359 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa)
ARHGAP10Rho GTPase-activating protein 10. (786 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (870 aa)
ELMO2Engulfment and cell motility protein 2 isoform X1. (732 aa)
PTK2Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1052 aa)
ITGA5Integrin alpha-5; Belongs to the integrin alpha chain family. (1104 aa)
SEPT11Septin-11 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (429 aa)
WASF1wiskott-Aldrich syndrome protein family member 1 isoform X1. (559 aa)
VCLVinculin isoform X1. (1134 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (724 aa)
SEPT8Septin-8 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (483 aa)
CD2APCD2-associated protein. (639 aa)
METHepatocyte growth factor receptor. (1382 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
SHC3SHC-transforming protein 3. (587 aa)
MAD2L2Mitotic spindle assembly checkpoint protein MAD2B. (211 aa)
CDC42Cell division control protein 42 homolog isoform X1. (191 aa)
DNM3Dynamin-3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (825 aa)
CBLE3 ubiquitin-protein ligase CBL. (910 aa)
SEPT2Septin-2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (361 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1 isoform X2. (865 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa)
ILKIntegrin-linked protein kinase isoform X1. (452 aa)
LOC101381905Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (218 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1640 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (243 aa)
LOC101366544LOW QUALITY PROTEIN: ras-related C3 botulinum toxin substrate 1-like. (145 aa)
SEPT9Septin-9 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (585 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa)
LOC101381443Uncharacterized protein LOC101381443 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (795 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
CTNNA1Catenin alpha-1 isoform X1. (929 aa)
LOC101365594Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (167 aa)
DNM2Dynamin-2 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (881 aa)
LOC101366585Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
LOC101375473LOW QUALITY PROTEIN: uncharacterized protein LOC101375473. (703 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
DOCK1Dedicator of cytokinesis protein 1 isoform X1; Belongs to the DOCK family. (1889 aa)
WASLNeural Wiskott-Aldrich syndrome protein isoform X1. (519 aa)
SEPT6Septin-6 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (466 aa)
SRCTyrosine-protein kinase. (553 aa)
CTNNA2Catenin alpha-2 isoform X1. (953 aa)
ELMO1Engulfment and cell motility protein 1 isoform X1. (742 aa)
CTTNSrc substrate cortactin. (539 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.