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| | DDX58 | Probable ATP-dependent RNA helicase DDX58. (927 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon. (718 aa) |
| | E2F1 | Transcription factor E2F1. (431 aa) |
| | CLDN11 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa) |
| | CFLAR | CASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family. (482 aa) |
| | CASP8 | Caspase-8 isoform X1; Belongs to the peptidase C14A family. (486 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | RELA | Transcription factor p65. (539 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (219 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | BAD | Bcl2-associated agonist of cell death. (168 aa) |
| | EIF2AK1 | Eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1. (633 aa) |
| | GRB2 | Growth factor receptor-bound protein 2 isoform X1. (217 aa) |
| | E2F2 | Transcription factor E2F2. (442 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | SCARB1 | Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (509 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | ARAF | Serine/threonine-protein kinase A-Raf. (606 aa) |
| | RNASEL | 2-5A-dependent ribonuclease. (725 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | CASP9 | Caspase-9 isoform X1; Belongs to the peptidase C14A family. (451 aa) |
| | LOC101386944 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit 1. (315 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | CLDN7 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | TYK2 | Tyrosine-protein kinase. (1203 aa) |
| | LDLR | Low-density lipoprotein receptor. (926 aa) |
| | CLDN3 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | CLDN4 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa) |
| | YWHAG | 14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa) |
| | CLDN15 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (232 aa) |
| | RB1 | Retinoblastoma-associated protein. (936 aa) |
| | NR1H3 | Oxysterols receptor LXR-alpha isoform X1. (447 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) |
| | YWHAH | 14-3-3 protein eta isoform X1; Belongs to the 14-3-3 family. (246 aa) |
| | EIF2AK4 | Eukaryotic translation initiation factor 2-alpha kinase 4. (1652 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (507 aa) |
| | STAT2 | Signal transducer and activator of transcription. (854 aa) |
| | YWHAQ | 14-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa) |
| | CDK4 | Cyclin-dependent kinase 4 isoform X1; Belongs to the protein kinase superfamily. (340 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa) |
| | IRF9 | Interferon regulatory factor 9 isoform X1. (484 aa) |
| | CLDN9 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa) |
| | CLDN6 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa) |
| | OCLN | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (521 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) |
| | IRF7 | Interferon regulatory factor 7 isoform X1. (517 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | CD81 | Tetraspanin. (339 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1250 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | IFNB1 | Interferon beta. (182 aa) |
| | LOC101374322 | Interferon alpha-1/2-like. (187 aa) |
| | LOC101374610 | Interferon alpha-14-like. (182 aa) |
| | LOC101379735 | Interferon beta-like. (174 aa) |
| | IFNAR2 | Interferon alpha/beta receptor 2. (517 aa) |
| | CLDN8 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa) |
| | CLDN17 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa) |
| | IFNAR1 | Interferon alpha/beta receptor 1. (560 aa) |
| | CXCL10 | C-X-C motif chemokine. (98 aa) |
| | MX1 | Interferon-induced GTP-binding protein Mx1 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (658 aa) |
| | MX2 | Interferon-induced GTP-binding protein Mx2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (712 aa) |
| | CLDN19 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa) |
| | BID | BH3-interacting domain death agonist. (99 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer. (211 aa) |
| | SOS2 | Son of sevenless homolog 2 isoform X1. (1333 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1. (665 aa) |
| | CLDN10 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (231 aa) |
| | LOC101382469 | Claudin-9-like. (214 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) |
| | IRF3 | Interferon regulatory factor 3. (420 aa) |
| | SOS1 | Son of sevenless homolog 1 isoform X1. (1333 aa) |
| | EIF2AK2 | Interferon-induced, double-stranded RNA-activated protein kinase. (540 aa) |
| | OAS2 | 2'-5'-oligoadenylate synthase 2. (685 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthase 1. (399 aa) |
| | OAS3 | 2'-5'-oligoadenylate synthase 3. (1089 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (277 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (503 aa) |
| | TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (910 aa) |
| | IFNA5 | Interferon alpha-5. (183 aa) |
| | LOC101377641 | Interferon alpha-1/2-like. (187 aa) |
| | CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | CLDN16 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (237 aa) |
| | IFIT1B | LOW QUALITY PROTEIN: interferon-induced protein with tetratricopeptide repeats 1B. (499 aa) |
| | CLDN23 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (291 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa) |
| | IFIT1 | Interferon-induced protein with tetratricopeptide repeats 1. (480 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | E2F3 | Transcription factor E2F3 isoform X1. (468 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (451 aa) |
| | YWHAB | 14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (244 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1113 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa) |
| | BAX | Apoptosis regulator BAX isoform X1. (192 aa) |
| | CLDN2 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | LOC101367134 | GTPase HRas-like. (177 aa) |
| | CLDN24 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa) |
| | PPARA | Peroxisome proliferator-activated receptor alpha. (468 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) |
| | SOCS3 | Suppressor of cytokine signaling 3. (225 aa) |
| | CLDN25 | Putative claudin-25. (228 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | CLDN20 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | CLDN14 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (237 aa) |
| | RSAD2 | Radical S-adenosyl methionine domain-containing protein 2. (363 aa) |
| | CTNNB1 | Catenin beta-1 isoform X1. (781 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (310 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa) |
| | MAVS | Mitochondrial antiviral-signaling protein. (518 aa) |
| | LOC105757464 | Claudin-9-like. (243 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | STAT1 | Signal transducer and activator of transcription. (750 aa) |
| | PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (424 aa) |
| | YWHAZ | 14-3-3 protein zeta/delta isoform X1; Belongs to the 14-3-3 family. (256 aa) |
| | LOC101386882 | LOW QUALITY PROTEIN: cytochrome c, testis-specific-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | YWHAE | 14-3-3 protein epsilon isoform X1; Belongs to the 14-3-3 family. (256 aa) |
| | EIF3E | Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (450 aa) |
| | LOC101371803 | Claudin-6-like. (200 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6. (319 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (161 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1. (324 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1210 aa) |
| | RXRA | Retinoic acid receptor RXR-alpha isoform X1. (497 aa) |
| | JAK1 | Tyrosine-protein kinase. (1153 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa) |
| | PIAS1 | E3 SUMO-protein ligase PIAS1 isoform X1. (655 aa) |
| | PPP2R1B | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1. (694 aa) |
| | TBK1 | Serine/threonine-protein kinase TBK1 isoform X1. (782 aa) |
| | BRAF | Serine/threonine-protein kinase B-raf. (772 aa) |
| | IKBKG | NF-kappa-B essential modulator isoform X1. (457 aa) |
| | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1. (590 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1209 aa) |
