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| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | CREB3 | Cyclic AMP-responsive element-binding protein 3. (352 aa) |
| | DDX58 | Probable ATP-dependent RNA helicase DDX58. (927 aa) |
| | STAT4 | Signal transducer and activator of transcription. (748 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon. (718 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | E2F1 | Transcription factor E2F1. (431 aa) |
| | NFATC3 | Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1072 aa) |
| | CASP8 | Caspase-8 isoform X1; Belongs to the peptidase C14A family. (486 aa) |
| | RELA | Transcription factor p65. (539 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (219 aa) |
| | BAD | Bcl2-associated agonist of cell death. (168 aa) |
| | TLR2 | Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa) |
| | GRB2 | Growth factor receptor-bound protein 2 isoform X1. (217 aa) |
| | E2F2 | Transcription factor E2F2. (442 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | IRAK4 | Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | TGFB1 | Transforming growth factor beta-1. (287 aa) |
| | ARAF | Serine/threonine-protein kinase A-Raf. (606 aa) |
| | ELK1 | ETS domain-containing protein Elk-1. (435 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | CASP9 | Caspase-9 isoform X1; Belongs to the peptidase C14A family. (451 aa) |
| | IL6 | Interleukin-6 isoform X1. (212 aa) |
| | LOC101386944 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | EP300 | Histone acetyltransferase p300. (2421 aa) |
| | ATF4 | Cyclic AMP-dependent transcription factor ATF-4. (351 aa) |
| | TAB1 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (504 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | SLC10A1 | Sodium/bile acid cotransporter. (349 aa) |
| | BCL2 | Apoptosis regulator Bcl-2. (235 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | TYK2 | Tyrosine-protein kinase. (1203 aa) |
| | FOS | Proto-oncogene c-Fos isoform X1. (380 aa) |
| | TGFB3 | Transforming growth factor beta-3. (461 aa) |
| | RB1 | Retinoblastoma-associated protein. (936 aa) |
| | CREB3L1 | Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa) |
| | DDB2 | DNA damage-binding protein 2 isoform X1. (426 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) |
| | CCNA1 | cyclin-A1; Belongs to the cyclin family. (421 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (507 aa) |
| | LOC101385791 | ATP-dependent RNA helicase DDX3X-like isoform X1; Belongs to the DEAD box helicase family. (663 aa) |
| | CCNA2 | cyclin-A2 isoform X1; Belongs to the cyclin family. (433 aa) |
| | STAT6 | Signal transducer and activator of transcription. (844 aa) |
| | STAT2 | Signal transducer and activator of transcription. (854 aa) |
| | YWHAQ | 14-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa) |
| | NFATC4 | Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1. (930 aa) |
| | EGR3 | Early growth response protein 3 isoform X1. (387 aa) |
| | CREB3L4 | Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (393 aa) |
| | CREBBP | CREB-binding protein isoform X1. (2433 aa) |
| | IRF7 | Interferon regulatory factor 7 isoform X1. (517 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1250 aa) |
| | TAB2 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | JAK3 | Tyrosine-protein kinase. (1104 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa) |
| | MAP2K3 | Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | MMP9 | Matrix metalloproteinase-9. (704 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa) |
| | IFNB1 | Interferon beta. (182 aa) |
| | LOC101374322 | Interferon alpha-1/2-like. (187 aa) |
| | LOC101374610 | Interferon alpha-14-like. (182 aa) |
| | LOC101379735 | Interferon beta-like. (174 aa) |
| | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | IFNAR1 | Interferon alpha/beta receptor 1. (560 aa) |
| | BID | BH3-interacting domain death agonist. (99 aa) |
| | JAK2 | Tyrosine-protein kinase. (1130 aa) |
| | SOS2 | Son of sevenless homolog 2 isoform X1. (1333 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1508 aa) |
| | TIRAP | Toll/interleukin-1 receptor domain-containing adapter protein. (221 aa) |
| | IRAK1 | Interleukin-1 receptor-associated kinase 1 isoform X1. (724 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | IRF3 | Interferon regulatory factor 3. (420 aa) |
| | SOS1 | Son of sevenless homolog 1 isoform X1. (1333 aa) |
| | DDB1 | DNA damage-binding protein 1 isoform X1. (1193 aa) |
| | IFIH1 | Interferon-induced helicase C domain-containing protein 1. (1026 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | STAT5A | Signal transducer and activator of transcription. (794 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | CCNE2 | G1/S-specific cyclin-E2; Belongs to the cyclin family. (404 aa) |
| | PTK2B | Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | HSPG2 | Basement membrane-specific heparan sulfate proteoglycan core protein. (4510 aa) |
| | MAP2K7 | Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (277 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (427 aa) |
| | TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (910 aa) |
| | IFNA5 | Interferon alpha-5. (183 aa) |
| | LOC101377641 | Interferon alpha-1/2-like. (187 aa) |
| | NFATC1 | Nuclear factor of activated T-cells, cytoplasmic 1. (823 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | E2F3 | Transcription factor E2F3 isoform X1. (468 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5. (369 aa) |
| | LOC101374369 | Voltage-dependent anion-selective channel protein 3-like. (283 aa) |
| | YWHAB | 14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (244 aa) |
| | ATP6AP1 | V-type proton ATPase subunit S1. (464 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | NFATC2 | Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (920 aa) |
| | JUN | Transcription factor AP-1 isoform X1; Belongs to the bZIP family. (335 aa) |
| | BAX | Apoptosis regulator BAX isoform X1. (192 aa) |
| | ATF6B | Cyclic AMP-dependent transcription factor ATF-6 beta isoform X2. (711 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | LOC101367134 | GTPase HRas-like. (177 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) |
| | TLR4 | Toll-like receptor 4; Belongs to the Toll-like receptor family. (833 aa) |
| | BIRC5 | Baculoviral IAP repeat-containing protein 5. (142 aa) |
| | CREB3L2 | Cyclic AMP-responsive element-binding protein 3-like protein 2. (519 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa) |
| | CCNE1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa) |
| | LOC101367407 | Uncharacterized protein LOC101367407. (575 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa) |
| | MAVS | Mitochondrial antiviral-signaling protein. (518 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | DDX3X | ATP-dependent RNA helicase DDX3X isoform X1; Belongs to the DEAD box helicase family. (674 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | STAT1 | Signal transducer and activator of transcription. (750 aa) |
| | YWHAZ | 14-3-3 protein zeta/delta isoform X1; Belongs to the 14-3-3 family. (256 aa) |
| | TICAM2 | TIR domain-containing adapter molecule 2. (233 aa) |
| | LOC101386882 | LOW QUALITY PROTEIN: cytochrome c, testis-specific-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | EGR2 | E3 SUMO-protein ligase EGR2 isoform X1. (484 aa) |
| | SRC | Tyrosine-protein kinase. (553 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6. (319 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (161 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) |
| | STAT5B | Signal transducer and activator of transcription. (818 aa) |
| | JAK1 | Tyrosine-protein kinase. (1153 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa) |
| | CASP10 | Caspase-10 isoform X1; Belongs to the peptidase C14A family. (497 aa) |
| | TBK1 | Serine/threonine-protein kinase TBK1 isoform X1. (782 aa) |
| | BRAF | Serine/threonine-protein kinase B-raf. (772 aa) |
| | IKBKG | NF-kappa-B essential modulator isoform X1. (457 aa) |
| | VDAC3 | Voltage-dependent anion-selective channel protein 3 isoform X1. (289 aa) |
| | LOC101382304 | Caspase-12-like; Belongs to the peptidase C14A family. (391 aa) |
| | MAP2K4 | Dual specificity mitogen-activated protein kinase kinase 4 isoform X1; Belongs to the protein kinase superfamily. (411 aa) |
