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| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | CBLB | E3 ubiquitin-protein ligase CBL-B. (982 aa) |
| | DDX58 | Probable ATP-dependent RNA helicase DDX58. (927 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon. (718 aa) |
| | CSNK2A1 | Casein kinase II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (391 aa) |
| | BCL2L1 | Bcl-2-like protein 1 isoform X1. (233 aa) |
| | CASP8 | Caspase-8 isoform X1; Belongs to the peptidase C14A family. (486 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | RELA | Transcription factor p65. (539 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (219 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | BAD | Bcl2-associated agonist of cell death. (168 aa) |
| | EIF2AK1 | Eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1. (633 aa) |
| | TLR2 | Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | CSNK2A2 | Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (350 aa) |
| | IRAK4 | Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | IL2RG | Cytokine receptor common subunit gamma. (374 aa) |
| | CASP9 | Caspase-9 isoform X1; Belongs to the peptidase C14A family. (451 aa) |
| | IL6 | Interleukin-6 isoform X1. (212 aa) |
| | LOC101386944 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit 1. (315 aa) |
| | BCL2 | Apoptosis regulator Bcl-2. (235 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | TYK2 | Tyrosine-protein kinase. (1203 aa) |
| | FOS | Proto-oncogene c-Fos isoform X1. (380 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (270 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (265 aa) |
| | EIF2AK4 | Eukaryotic translation initiation factor 2-alpha kinase 4. (1652 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (507 aa) |
| | BBC3 | Bcl-2-binding component 3. (193 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa) |
| | STAT2 | Signal transducer and activator of transcription. (854 aa) |
| | CDK4 | Cyclin-dependent kinase 4 isoform X1; Belongs to the protein kinase superfamily. (340 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa) |
| | IRF9 | Interferon regulatory factor 9 isoform X1. (484 aa) |
| | LOC101364797 | Uncharacterized protein LOC101364797. (416 aa) |
| | ADAR | Double-stranded RNA-specific adenosine deaminase. (1149 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) |
| | IRF7 | Interferon regulatory factor 7 isoform X1. (517 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1250 aa) |
| | TAB2 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | JAK3 | Tyrosine-protein kinase. (1104 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) |
| | IFNB1 | Interferon beta. (182 aa) |
| | LOC101374322 | Interferon alpha-1/2-like. (187 aa) |
| | LOC101374610 | Interferon alpha-14-like. (182 aa) |
| | LOC101379735 | Interferon beta-like. (174 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa) |
| | IFNAR2 | Interferon alpha/beta receptor 2. (517 aa) |
| | IFNAR1 | Interferon alpha/beta receptor 1. (560 aa) |
| | RCHY1 | RING finger and CHY zinc finger domain-containing protein 1 isoform X1. (261 aa) |
| | MX1 | Interferon-induced GTP-binding protein Mx1 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (658 aa) |
| | MX2 | Interferon-induced GTP-binding protein Mx2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (712 aa) |
| | BID | BH3-interacting domain death agonist. (99 aa) |
| | CD28 | T-cell-specific surface glycoprotein CD28. (221 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer. (211 aa) |
| | SLAMF1 | Signaling lymphocytic activation molecule. (338 aa) |
| | CCND3 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (292 aa) |
| | LOC101362469 | WD repeat-containing protein 5-like. (465 aa) |
| | IRAK1 | Interleukin-1 receptor-associated kinase 1 isoform X1. (724 aa) |
| | TLR7 | Toll-like receptor 7; Belongs to the Toll-like receptor family. (1050 aa) |
| | HSPA2 | Heat shock-related 70 kDa protein 2; Belongs to the heat shock protein 70 family. (638 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) |
| | IRF3 | Interferon regulatory factor 3. (420 aa) |
| | EIF2AK2 | Interferon-induced, double-stranded RNA-activated protein kinase. (540 aa) |
| | IFIH1 | Interferon-induced helicase C domain-containing protein 1. (1026 aa) |
| | TNFAIP3 | Tumor necrosis factor alpha-induced protein 3. (790 aa) |
| | OAS2 | 2'-5'-oligoadenylate synthase 2. (685 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthase 1. (399 aa) |
| | OAS3 | 2'-5'-oligoadenylate synthase 3. (1089 aa) |
| | STAT5A | Signal transducer and activator of transcription. (794 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | IL2RB | Interleukin-2 receptor subunit beta. (550 aa) |
| | CCNE2 | G1/S-specific cyclin-E2; Belongs to the cyclin family. (404 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B. (198 aa) |
| | CD209 | CD209 antigen isoform X1. (249 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (277 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (427 aa) |
| | IFNA5 | Interferon alpha-5. (183 aa) |
| | LOC101377641 | Interferon alpha-1/2-like. (187 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | EIF3H | Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (352 aa) |
| | GNB2L1 | Guanine nucleotide-binding protein subunit beta-2-like 1 isoform X1. (317 aa) |
| | HSPA8 | Heat shock cognate 71 kDa protein isoform X1; Belongs to the heat shock protein 70 family. (654 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1113 aa) |
| | JUN | Transcription factor AP-1 isoform X1; Belongs to the bZIP family. (335 aa) |
| | CD3E | T-cell surface glycoprotein CD3 epsilon chain. (190 aa) |
| | CD3G | T-cell surface glycoprotein CD3 gamma chain isoform X1. (180 aa) |
| | CD3D | T-cell surface glycoprotein CD3 delta chain. (171 aa) |
| | BAX | Apoptosis regulator BAX isoform X1. (192 aa) |
| | CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa) |
| | LOC101376406 | Heat shock 70 kDa protein 1; Belongs to the heat shock protein 70 family. (641 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa) |
| | RAB9B | Ras-related protein Rab-9B. (201 aa) |
| | CCND2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) |
| | TLR4 | Toll-like receptor 4; Belongs to the Toll-like receptor family. (833 aa) |
| | CCNE1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa) |
| | MSN | Moesin. (577 aa) |
| | LOC101367407 | Uncharacterized protein LOC101367407. (575 aa) |
| | NFKBIB | NF-kappa-B inhibitor beta isoform X1. (359 aa) |
| | MAVS | Mitochondrial antiviral-signaling protein. (518 aa) |
| | LOC101375744 | LOW QUALITY PROTEIN: heat shock cognate 71 kDa protein-like; Belongs to the heat shock protein 70 family. (656 aa) |
| | STAT1 | Signal transducer and activator of transcription. (750 aa) |
| | HSPA6 | LOW QUALITY PROTEIN: heat shock 70 kDa protein 6; Belongs to the heat shock protein 70 family. (688 aa) |
| | LOC101386882 | LOW QUALITY PROTEIN: cytochrome c, testis-specific-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (643 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6. (319 aa) |
| | RAB9A | Ras-related protein Rab-9A. (201 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1. (324 aa) |
| | LOC101370160 | Toll-like receptor 9 isoform X1. (1056 aa) |
| | STAT5B | Signal transducer and activator of transcription. (818 aa) |
| | IL2RA | Interleukin-2 receptor subunit alpha. (422 aa) |
| | JAK1 | Tyrosine-protein kinase. (1153 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa) |
| | TBK1 | Serine/threonine-protein kinase TBK1 isoform X1. (782 aa) |
| | IKBKG | NF-kappa-B essential modulator isoform X1. (457 aa) |
| | HSPA1L | Heat shock 70 kDa protein 1-like isoform X1; Belongs to the heat shock protein 70 family. (661 aa) |
| | CD46 | Membrane cofactor protein. (471 aa) |
