STRINGSTRING
HPSE HPSE WNT11 WNT11 PAK1 PAK1 HCLS1 HCLS1 PLCG2 PLCG2 ITGB5 ITGB5 ITGAV ITGAV HGF HGF CCND1 CCND1 PPP1CA PPP1CA COL1A2 COL1A2 FZD1 FZD1 ACTB ACTB RAC1 RAC1 TLR2 TLR2 GRB2 GRB2 FGFR1 FGFR1 SLC9A1 SLC9A1 PPP1CB PPP1CB ERBB2 ERBB2 COL1A1 COL1A1 MAP2K2 MAP2K2 WNT7A WNT7A AKT1 AKT1 MMP2 MMP2 PPP1CC PPP1CC KDR KDR AKT2 AKT2 TGFB1 TGFB1 PXN PXN ARAF ARAF ELK1 ELK1 MAPK3 MAPK3 PIK3CD PIK3CD RPS6KB1 RPS6KB1 HBEGF HBEGF WNT8A WNT8A FLNC FLNC SMO SMO IQGAP1 IQGAP1 PIK3CA PIK3CA TP53 TP53 PRKCB PRKCB PRKACA PRKACA FZD9 FZD9 RHOA RHOA AKT3 AKT3 THBS1 THBS1 MAPK1 MAPK1 PIK3R3 PIK3R3 WNT10B WNT10B WNT1 WNT1 GPC3 GPC3 RDX RDX FN1 FN1 WNT2B WNT2B ERBB3 ERBB3 ITGB1 ITGB1 ROCK2 ROCK2 WNT8B WNT8B FZD6 FZD6 WNT10A WNT10A WNT6 WNT6 IHH IHH CAMK2A CAMK2A PDPK1 PDPK1 TFAP4 TFAP4 NUDT16L1 NUDT16L1 SHH SHH HRAS HRAS IGF2 IGF2 WNT16 WNT16 PIK3R2 PIK3R2 IL12B IL12B PPP1R12C PPP1R12C MMP9 MMP9 FZD5 FZD5 SDC1 SDC1 VAV3 VAV3 PTK2 PTK2 RPS6 RPS6 MDM2 MDM2 FRS2 FRS2 CD44 CD44 ANK3 ANK3 ITGA5 ITGA5 EIF4B EIF4B TIAM1 TIAM1 WNT5A WNT5A ANK2 ANK2 CAMK2D CAMK2D WNT5B WNT5B PLAU PLAU WNT9A WNT9A WNT3A WNT3A GAB1 GAB1 FZD2 FZD2 LOC101382346 LOC101382346 PTCH1 PTCH1 SOS2 SOS2 PLAUR PLAUR WNT2 WNT2 MET MET CAV2 CAV2 CAV1 CAV1 SMAD2 SMAD2 HOXD10 HOXD10 PRKCG PRKCG MAPK11 MAPK11 MAPK12 MAPK12 MAPK13 MAPK13 MAPK14 MAPK14 RRAS RRAS SOS1 SOS1 PTPN11 PTPN11 TWIST2 TWIST2 STAT3 STAT3 NANOG NANOG ITGA2 ITGA2 LOC101364428 LOC101364428 ITGB3 ITGB3 WNT3 WNT3 MTOR MTOR WNT9B WNT9B VAV2 VAV2 DROSHA DROSHA FZD3 FZD3 CDC42 CDC42 HSPG2 HSPG2 WNT4 WNT4 HIF1A HIF1A FLNB FLNB FASLG FASLG PLCE1 PLCE1 ARHGEF12 ARHGEF12 CBL CBL GPC1 GPC1 CAV3 CAV3 IGF1 IGF1 MRAS MRAS PIK3CB PIK3CB PRKACB PRKACB HSPB2 HSPB2 PTPN6 PTPN6 CAMK2B CAMK2B FZD4 FZD4 SDC4 SDC4 TIMP3 TIMP3 SDC2 SDC2 MAP2K1 MAP2K1 FLNA FLNA TNF TNF LOC101367134 LOC101367134 TWIST1 TWIST1 LUM LUM FZD10 FZD10 DCN DCN RRAS2 RRAS2 TGFB2 TGFB2 HPSE2 HPSE2 PRKCA PRKCA ITPR2 ITPR2 WNT7B WNT7B PIK3R1 PIK3R1 TLR4 TLR4 LOC101385580 LOC101385580 LOC101362126 LOC101362126 EZR EZR FZD8 FZD8 MSN MSN CTNNB1 CTNNB1 VTN VTN LOC101366544 LOC101366544 LOC101367407 LOC101367407 LOC101377259 LOC101377259 VAV1 VAV1 RAF1 RAF1 LOC105757317 LOC105757317 ITPR1 ITPR1 LOC101371484 LOC101371484 LOC101366870 LOC101366870 NRAS NRAS FGF2 FGF2 CD63 CD63 ESR1 ESR1 LOC101363541 LOC101363541 DDX5 DDX5 IGF1R IGF1R PPP1R12A PPP1R12A LOC101374328 LOC101374328 SRC SRC VEGFA VEGFA ARHGEF1 ARHGEF1 ITPR3 ITPR3 FAS FAS CDKN1A CDKN1A ROCK1 ROCK1 MYC MYC PDCD4 PDCD4 PLCG1 PLCG1 FZD7 FZD7 LOC101364724 LOC101364724 CASP3 CASP3 BRAF BRAF CTTN CTTN EGFR EGFR RPS6KB2 RPS6KB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HPSEHeparanase isoform X1. (540 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
HCLS1Hematopoietic lineage cell-specific protein. (478 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
ITGAVIntegrin alpha-V isoform X1; Belongs to the integrin alpha chain family. (1053 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
COL1A2Collagen alpha-2(I) chain. (1367 aa)
FZD1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (648 aa)
ACTBActin, cytoplasmic 1 isoform X2. (375 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa)
TLR2Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
FGFR1Fibroblast growth factor receptor. (820 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
ERBB2Receptor protein-tyrosine kinase. (1281 aa)
COL1A1Collagen alpha-1(I) chain. (1460 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
MMP272 kDa type IV collagenase. (661 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
TGFB1Transforming growth factor beta-1. (287 aa)
PXNPaxillin; Belongs to the paxillin family. (557 aa)
ARAFSerine/threonine-protein kinase A-Raf. (606 aa)
ELK1ETS domain-containing protein Elk-1. (435 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
FLNCfilamin-C isoform X1. (2719 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1657 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (597 aa)
RHOATransforming protein RhoA isoform X1. (193 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
THBS1Thrombospondin-1 isoform X1. (1170 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (507 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
GPC3Glypican-3 isoform X1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
RDXRadixin isoform X1. (604 aa)
FN1Fibronectin isoform X1. (2476 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1339 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
FZD6Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
TFAP4Transcription factor AP-4. (337 aa)
NUDT16L1Protein syndesmos isoform X1. (211 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa)
HRASGTPase HRas isoform X1. (189 aa)
IGF2LOW QUALITY PROTEIN: insulin-like growth factor II. (198 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa)
PPP1R12CProtein phosphatase 1 regulatory subunit. (774 aa)
MMP9Matrix metalloproteinase-9. (704 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (590 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (307 aa)
VAV3Guanine nucleotide exchange factor VAV3 isoform X1. (875 aa)
PTK2Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1052 aa)
RPS640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
CD44CD44 antigen. (363 aa)
ANK3Ankyrin-3 isoform X1. (4376 aa)
ITGA5Integrin alpha-5; Belongs to the integrin alpha chain family. (1104 aa)
EIF4BEukaryotic translation initiation factor 4B isoform X1. (610 aa)
TIAM1T-lymphoma invasion and metastasis-inducing protein 1 isoform X1. (1591 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
ANK2Ankyrin-2 isoform X1. (4015 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta. (477 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
PLAUUrokinase-type plasminogen activator. (427 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (724 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
LOC101382346Cathepsin L1-like; Belongs to the peptidase C1 family. (333 aa)
PTCH1Protein patched homolog 1 isoform X1. (1452 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1333 aa)
PLAURUrokinase plasminogen activator surface receptor isoform X1. (338 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
METHepatocyte growth factor receptor. (1382 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
HOXD10Homeobox protein Hox-D10. (410 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
RRASRas-related protein R-Ras. (218 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1333 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
TWIST2Twist-related protein 2. (160 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
NANOGHomeobox protein NANOG. (407 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa)
LOC101364428Cathepsin L1-like; Belongs to the peptidase C1 family. (325 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2559 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform X1. (878 aa)
DROSHARibonuclease 3 isoform X1. (1374 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
CDC42Cell division control protein 42 homolog isoform X1. (191 aa)
HSPG2Basement membrane-specific heparan sulfate proteoglycan core protein. (4510 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (822 aa)
FLNBfilamin-B isoform X1. (2633 aa)
FASLGTumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (277 aa)
PLCE1Phosphoinositide phospholipase C. (2301 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1524 aa)
CBLE3 ubiquitin-protein ligase CBL. (910 aa)
GPC1Glypican-1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
IGF1Insulin-like growth factor I isoform X1. (187 aa)
MRASRas-related protein M-Ras. (208 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa)
HSPB2Heat shock protein beta-2; Belongs to the small heat shock protein (HSP20) family. (182 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (542 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
SDC4Syndecan-4. (202 aa)
TIMP3Metalloproteinase inhibitor 3 isoform X1. (211 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
FLNAfilamin-A. (2646 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
LOC101367134GTPase HRas-like. (177 aa)
TWIST1Twist-related protein 1. (196 aa)
LUMLumican. (338 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
DCNDecorin; May affect the rate of fibrils formation. (360 aa)
RRAS2Ras-related protein R-Ras2 isoform X1. (204 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
HPSE2Inactive heparanase-2. (403 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2639 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
TLR4Toll-like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
LOC101385580Inactive heparanase-2-like. (336 aa)
LOC101362126Cathepsin L1; Belongs to the peptidase C1 family. (334 aa)
EZREzrin isoform X1. (584 aa)
FZD8Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (689 aa)
MSNMoesin. (577 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
VTNLOW QUALITY PROTEIN: vitronectin. (400 aa)
LOC101366544LOW QUALITY PROTEIN: ras-related C3 botulinum toxin substrate 1-like. (145 aa)
LOC101367407Uncharacterized protein LOC101367407. (575 aa)
LOC101377259Ankyrin-1. (1805 aa)
VAV1Proto-oncogene vav isoform X1. (864 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
LOC105757317Mucin-1-like. (774 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2758 aa)
LOC101371484Receptor tyrosine-protein kinase erbB-4. (838 aa)
LOC101366870LOW QUALITY PROTEIN: homeobox protein NANOG-like. (300 aa)
NRASGTPase NRas. (189 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (377 aa)
CD63Tetraspanin. (249 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (597 aa)
LOC101363541LOW QUALITY PROTEIN: inactive heparanase-2-like. (604 aa)
DDX5Probable ATP-dependent RNA helicase DDX5 isoform X1; Belongs to the DEAD box helicase family. (614 aa)
IGF1RTyrosine-protein kinase receptor. (1304 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1029 aa)
LOC101374328Tyrosine-protein phosphatase non-receptor type 11-like. (581 aa)
SRCTyrosine-protein kinase. (553 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (587 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (974 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3 isoform X1. (2674 aa)
FASTumor necrosis factor receptor superfamily member 6. (319 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (161 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
PDCD4Programmed cell death protein 4 isoform X1. (469 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
LOC101364724Cathepsin L1-like; Belongs to the peptidase C1 family. (334 aa)
CASP3Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa)
BRAFSerine/threonine-protein kinase B-raf. (772 aa)
CTTNSrc substrate cortactin. (539 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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