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HPSE | Heparanase isoform X1. (540 aa) | ||||
WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) | ||||
PAK1 | Non-specific serine/threonine protein kinase. (544 aa) | ||||
HCLS1 | Hematopoietic lineage cell-specific protein. (478 aa) | ||||
PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) | ||||
ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (800 aa) | ||||
ITGAV | Integrin alpha-V isoform X1; Belongs to the integrin alpha chain family. (1053 aa) | ||||
HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa) | ||||
CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) | ||||
PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa) | ||||
COL1A2 | Collagen alpha-2(I) chain. (1367 aa) | ||||
FZD1 | Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (648 aa) | ||||
ACTB | Actin, cytoplasmic 1 isoform X2. (375 aa) | ||||
RAC1 | Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa) | ||||
TLR2 | Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa) | ||||
GRB2 | Growth factor receptor-bound protein 2 isoform X1. (217 aa) | ||||
FGFR1 | Fibroblast growth factor receptor. (820 aa) | ||||
SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa) | ||||
PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa) | ||||
ERBB2 | Receptor protein-tyrosine kinase. (1281 aa) | ||||
COL1A1 | Collagen alpha-1(I) chain. (1460 aa) | ||||
MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
MMP2 | 72 kDa type IV collagenase. (661 aa) | ||||
PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa) | ||||
KDR | Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
TGFB1 | Transforming growth factor beta-1. (287 aa) | ||||
PXN | Paxillin; Belongs to the paxillin family. (557 aa) | ||||
ARAF | Serine/threonine-protein kinase A-Raf. (606 aa) | ||||
ELK1 | ETS domain-containing protein Elk-1. (435 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) | ||||
RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) | ||||
HBEGF | Proheparin-binding EGF-like growth factor. (208 aa) | ||||
WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa) | ||||
FLNC | filamin-C isoform X1. (2719 aa) | ||||
SMO | Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa) | ||||
IQGAP1 | Ras GTPase-activating-like protein IQGAP1. (1657 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) | ||||
PRKACA | cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa) | ||||
FZD9 | Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (597 aa) | ||||
RHOA | Transforming protein RhoA isoform X1. (193 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
THBS1 | Thrombospondin-1 isoform X1. (1170 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) | ||||
PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (507 aa) | ||||
WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) | ||||
WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) | ||||
GPC3 | Glypican-3 isoform X1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa) | ||||
RDX | Radixin isoform X1. (604 aa) | ||||
FN1 | Fibronectin isoform X1. (2476 aa) | ||||
WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa) | ||||
ERBB3 | Receptor tyrosine-protein kinase erbB-3. (1339 aa) | ||||
ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (801 aa) | ||||
ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa) | ||||
WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) | ||||
FZD6 | Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa) | ||||
WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) | ||||
WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa) | ||||
IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa) | ||||
CAMK2A | Calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa) | ||||
PDPK1 | 3-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa) | ||||
TFAP4 | Transcription factor AP-4. (337 aa) | ||||
NUDT16L1 | Protein syndesmos isoform X1. (211 aa) | ||||
SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa) | ||||
HRAS | GTPase HRas isoform X1. (189 aa) | ||||
IGF2 | LOW QUALITY PROTEIN: insulin-like growth factor II. (198 aa) | ||||
WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa) | ||||
PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa) | ||||
IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) | ||||
PPP1R12C | Protein phosphatase 1 regulatory subunit. (774 aa) | ||||
MMP9 | Matrix metalloproteinase-9. (704 aa) | ||||
FZD5 | Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (590 aa) | ||||
SDC1 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (307 aa) | ||||
VAV3 | Guanine nucleotide exchange factor VAV3 isoform X1. (875 aa) | ||||
PTK2 | Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1052 aa) | ||||
RPS6 | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa) | ||||
MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa) | ||||
FRS2 | Fibroblast growth factor receptor substrate 2. (508 aa) | ||||
CD44 | CD44 antigen. (363 aa) | ||||
ANK3 | Ankyrin-3 isoform X1. (4376 aa) | ||||
ITGA5 | Integrin alpha-5; Belongs to the integrin alpha chain family. (1104 aa) | ||||
EIF4B | Eukaryotic translation initiation factor 4B isoform X1. (610 aa) | ||||
TIAM1 | T-lymphoma invasion and metastasis-inducing protein 1 isoform X1. (1591 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) | ||||
ANK2 | Ankyrin-2 isoform X1. (4015 aa) | ||||
CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta. (477 aa) | ||||
WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) | ||||
PLAU | Urokinase-type plasminogen activator. (427 aa) | ||||
WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) | ||||
WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa) | ||||
GAB1 | GRB2-associated-binding protein 1 isoform X1. (724 aa) | ||||
FZD2 | Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa) | ||||
LOC101382346 | Cathepsin L1-like; Belongs to the peptidase C1 family. (333 aa) | ||||
PTCH1 | Protein patched homolog 1 isoform X1. (1452 aa) | ||||
SOS2 | Son of sevenless homolog 2 isoform X1. (1333 aa) | ||||
PLAUR | Urokinase plasminogen activator surface receptor isoform X1. (338 aa) | ||||
WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) | ||||
MET | Hepatocyte growth factor receptor. (1382 aa) | ||||
CAV2 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa) | ||||
CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) | ||||
SMAD2 | Mothers against decapentaplegic homolog. (467 aa) | ||||
HOXD10 | Homeobox protein Hox-D10. (410 aa) | ||||
PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (364 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (367 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (366 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
RRAS | Ras-related protein R-Ras. (218 aa) | ||||
SOS1 | Son of sevenless homolog 1 isoform X1. (1333 aa) | ||||
PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa) | ||||
TWIST2 | Twist-related protein 2. (160 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (770 aa) | ||||
NANOG | Homeobox protein NANOG. (407 aa) | ||||
ITGA2 | Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa) | ||||
LOC101364428 | Cathepsin L1-like; Belongs to the peptidase C1 family. (325 aa) | ||||
ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (784 aa) | ||||
WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2559 aa) | ||||
WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) | ||||
VAV2 | Guanine nucleotide exchange factor VAV2 isoform X1. (878 aa) | ||||
DROSHA | Ribonuclease 3 isoform X1. (1374 aa) | ||||
FZD3 | Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) | ||||
CDC42 | Cell division control protein 42 homolog isoform X1. (191 aa) | ||||
HSPG2 | Basement membrane-specific heparan sulfate proteoglycan core protein. (4510 aa) | ||||
WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) | ||||
HIF1A | Hypoxia-inducible factor 1-alpha isoform X1. (822 aa) | ||||
FLNB | filamin-B isoform X1. (2633 aa) | ||||
FASLG | Tumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (277 aa) | ||||
PLCE1 | Phosphoinositide phospholipase C. (2301 aa) | ||||
ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1524 aa) | ||||
CBL | E3 ubiquitin-protein ligase CBL. (910 aa) | ||||
GPC1 | Glypican-1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa) | ||||
CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) | ||||
IGF1 | Insulin-like growth factor I isoform X1. (187 aa) | ||||
MRAS | Ras-related protein M-Ras. (208 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa) | ||||
PRKACB | cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa) | ||||
HSPB2 | Heat shock protein beta-2; Belongs to the small heat shock protein (HSP20) family. (182 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa) | ||||
CAMK2B | Calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (542 aa) | ||||
FZD4 | Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) | ||||
SDC4 | Syndecan-4. (202 aa) | ||||
TIMP3 | Metalloproteinase inhibitor 3 isoform X1. (211 aa) | ||||
SDC2 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa) | ||||
MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa) | ||||
FLNA | filamin-A. (2646 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) | ||||
LOC101367134 | GTPase HRas-like. (177 aa) | ||||
TWIST1 | Twist-related protein 1. (196 aa) | ||||
LUM | Lumican. (338 aa) | ||||
FZD10 | Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) | ||||
DCN | Decorin; May affect the rate of fibrils formation. (360 aa) | ||||
RRAS2 | Ras-related protein R-Ras2 isoform X1. (204 aa) | ||||
TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) | ||||
HPSE2 | Inactive heparanase-2. (403 aa) | ||||
PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa) | ||||
ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2639 aa) | ||||
WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) | ||||
PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) | ||||
TLR4 | Toll-like receptor 4; Belongs to the Toll-like receptor family. (833 aa) | ||||
LOC101385580 | Inactive heparanase-2-like. (336 aa) | ||||
LOC101362126 | Cathepsin L1; Belongs to the peptidase C1 family. (334 aa) | ||||
EZR | Ezrin isoform X1. (584 aa) | ||||
FZD8 | Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (689 aa) | ||||
MSN | Moesin. (577 aa) | ||||
CTNNB1 | Catenin beta-1 isoform X1. (781 aa) | ||||
VTN | LOW QUALITY PROTEIN: vitronectin. (400 aa) | ||||
LOC101366544 | LOW QUALITY PROTEIN: ras-related C3 botulinum toxin substrate 1-like. (145 aa) | ||||
LOC101367407 | Uncharacterized protein LOC101367407. (575 aa) | ||||
LOC101377259 | Ankyrin-1. (1805 aa) | ||||
VAV1 | Proto-oncogene vav isoform X1. (864 aa) | ||||
RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa) | ||||
LOC105757317 | Mucin-1-like. (774 aa) | ||||
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2758 aa) | ||||
LOC101371484 | Receptor tyrosine-protein kinase erbB-4. (838 aa) | ||||
LOC101366870 | LOW QUALITY PROTEIN: homeobox protein NANOG-like. (300 aa) | ||||
NRAS | GTPase NRas. (189 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (377 aa) | ||||
CD63 | Tetraspanin. (249 aa) | ||||
ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (597 aa) | ||||
LOC101363541 | LOW QUALITY PROTEIN: inactive heparanase-2-like. (604 aa) | ||||
DDX5 | Probable ATP-dependent RNA helicase DDX5 isoform X1; Belongs to the DEAD box helicase family. (614 aa) | ||||
IGF1R | Tyrosine-protein kinase receptor. (1304 aa) | ||||
PPP1R12A | Protein phosphatase 1 regulatory subunit. (1029 aa) | ||||
LOC101374328 | Tyrosine-protein phosphatase non-receptor type 11-like. (581 aa) | ||||
SRC | Tyrosine-protein kinase. (553 aa) | ||||
VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (587 aa) | ||||
ARHGEF1 | Rho guanine nucleotide exchange factor 1. (974 aa) | ||||
ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3 isoform X1. (2674 aa) | ||||
FAS | Tumor necrosis factor receptor superfamily member 6. (319 aa) | ||||
CDKN1A | Cyclin-dependent kinase inhibitor 1. (161 aa) | ||||
ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) | ||||
PDCD4 | Programmed cell death protein 4 isoform X1. (469 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) | ||||
FZD7 | Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) | ||||
LOC101364724 | Cathepsin L1-like; Belongs to the peptidase C1 family. (334 aa) | ||||
CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa) | ||||
BRAF | Serine/threonine-protein kinase B-raf. (772 aa) | ||||
CTTN | Src substrate cortactin. (539 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1209 aa) | ||||
RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa) |