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| | CCNG1 | cyclin-G1; Belongs to the cyclin family. (295 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | RECK | Reversion-inducing cysteine-rich protein with Kazal motifs isoform X1. (971 aa) |
| | GLS | Glutaminase kidney isoform, mitochondrial isoform X1. (678 aa) |
| | ABL1 | Tyrosine-protein kinase. (1150 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (552 aa) |
| | E2F1 | Transcription factor E2F1. (431 aa) |
| | VIM | Vimentin isoform X1; Belongs to the intermediate filament family. (466 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) |
| | EFNA5 | ephrin-A5; Belongs to the ephrin family. (228 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | SIRT1 | NAD-dependent protein deacetylase sirtuin-1 isoform X1. (740 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | CDCA5 | Sororin. (253 aa) |
| | FSCN1 | Fascin. (493 aa) |
| | GRB2 | Growth factor receptor-bound protein 2 isoform X1. (217 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (798 aa) |
| | DICER1 | Endoribonuclease Dicer isoform X1; Belongs to the helicase family. Dicer subfamily. (1923 aa) |
| | E2F2 | Transcription factor E2F2. (442 aa) |
| | LOC101385960 | Heterogeneous nuclear ribonucleoprotein K-like. (466 aa) |
| | DNMT3A | DNA (Cytosine-5)-methyltransferase 3A isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (909 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1281 aa) |
| | IGF2BP1 | Insulin-like growth factor 2 mRNA-binding protein 1 isoform X1. (577 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | EFNA2 | ephrin-A2; Belongs to the ephrin family. (214 aa) |
| | APC2 | Adenomatous polyposis coli protein 2. (2267 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (808 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (595 aa) |
| | SHC4 | SHC-transforming protein 4. (630 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | EP300 | Histone acetyltransferase p300. (2421 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | CDC25C | M-phase inducer phosphatase 3. (525 aa) |
| | HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa) |
| | MARCKS | Myristoylated alanine-rich C-kinase substrate. (333 aa) |
| | BCL2 | Apoptosis regulator Bcl-2. (235 aa) |
| | CDC25B | M-phase inducer phosphatase 2 isoform X1. (574 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | DNMT1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1649 aa) |
| | RHOA | Transforming protein RhoA isoform X1. (193 aa) |
| | CDC25A | M-phase inducer phosphatase 1 isoform X1. (524 aa) |
| | BMF | Bcl-2-modifying factor. (184 aa) |
| | THBS1 | Thrombospondin-1 isoform X1. (1170 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | CRKL | Crk-like protein. (303 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (507 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa) |
| | RDX | Radixin isoform X1. (604 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (216 aa) |
| | APC | Adenomatous polyposis coli protein isoform X1. (2844 aa) |
| | ERBB3 | Receptor tyrosine-protein kinase erbB-3. (1339 aa) |
| | GLS2 | Glutaminase liver isoform, mitochondrial isoform X1. (602 aa) |
| | ZEB1 | Zinc finger E-box-binding homeobox 1 isoform X1. (1126 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) |
| | BCL2L2 | Bcl-2-like protein 2. (193 aa) |
| | ZFPM2 | Zinc finger protein ZFPM2 isoform X1. (1151 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1098 aa) |
| | EFNA1 | ephrin-A1 isoform X1; Belongs to the ephrin family. (206 aa) |
| | EFNA3 | ephrin-A3 isoform X1; Belongs to the ephrin family. (238 aa) |
| | UBE2I | SUMO-conjugating enzyme UBC9 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | CREBBP | CREB-binding protein isoform X1. (2433 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | CRK | Adapter molecule crk isoform X1. (304 aa) |
| | MCL1 | Induced myeloid leukemia cell differentiation protein Mcl-1 isoform X1. (350 aa) |
| | RPTOR | Regulatory-associated protein of mTOR isoform X1. (1335 aa) |
| | FOXP1 | Forkhead box protein P1 isoform X1. (693 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa) |
| | MMP9 | Matrix metalloproteinase-9. (704 aa) |
| | PTGS2 | Prostaglandin G/H synthase 2. (604 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa) |
| | CD44 | CD44 antigen. (363 aa) |
| | ITGA5 | Integrin alpha-5; Belongs to the integrin alpha chain family. (1104 aa) |
| | HDAC1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa) |
| | SLC7A1 | High affinity cationic amino acid transporter 1. (629 aa) |
| | PLAU | Urokinase-type plasminogen activator. (427 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa) |
| | HNRNPK | Heterogeneous nuclear ribonucleoprotein K isoform X1. (464 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer. (211 aa) |
| | SOS2 | Son of sevenless homolog 2 isoform X1. (1333 aa) |
| | NOTCH3 | Neurogenic locus notch homolog protein 3. (2322 aa) |
| | MET | Hepatocyte growth factor receptor. (1382 aa) |
| | EZH2 | Histone-lysine N-methyltransferase EZH2 isoform X1. (751 aa) |
| | ABCC1 | Multidrug resistance-associated protein 1. (1531 aa) |
| | TRIM71 | E3 ubiquitin-protein ligase TRIM71. (869 aa) |
| | HOXD10 | Homeobox protein Hox-D10. (410 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | IRS2 | Insulin receptor substrate 2. (1327 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | IRS1 | Insulin receptor substrate 1. (1233 aa) |
| | PIM1 | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa) |
| | LOC101365942 | Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (543 aa) |
| | SOS1 | Son of sevenless homolog 1 isoform X1. (1333 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1056 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | NOTCH1 | Neurogenic locus notch homolog protein 1. (2567 aa) |
| | CCNE2 | G1/S-specific cyclin-E2; Belongs to the cyclin family. (404 aa) |
| | ABCB1 | Multidrug resistance protein 1 isoform X1. (1280 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B. (198 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (784 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2559 aa) |
| | FZD3 | Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | TPM1 | Tropomyosin alpha-1 chain isoform X1; Belongs to the tropomyosin family. (284 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (733 aa) |
| | DDIT4 | DNA damage-inducible transcript 4 protein. (231 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | E2F3 | Transcription factor E2F3 isoform X1. (468 aa) |
| | SOX4 | Transcription factor SOX. (472 aa) |
| | MMP16 | Matrix metalloproteinase-16. (607 aa) |
| | TIMP3 | Metalloproteinase inhibitor 3 isoform X1. (211 aa) |
| | PDGFA | Platelet-derived growth factor subunit A isoform X1; Belongs to the PDGF/VEGF growth factor family. (211 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa) |
| | TNC | Tenascin isoform X1. (2201 aa) |
| | LOC101367134 | GTPase HRas-like. (177 aa) |
| | NOTCH4 | Neurogenic locus notch homolog protein 4 isoform X1. (1996 aa) |
| | HMGA2 | High mobility group protein HMGI-C. (109 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa) |
| | CCND2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) |
| | NOTCH2 | Neurogenic locus notch homolog protein 2. (2471 aa) |
| | LOC101384402 | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (514 aa) |
| | HMOX1 | Heme oxygenase 1. (322 aa) |
| | TNN | tenascin-N. (1296 aa) |
| | TNR | tenascin-R. (1358 aa) |
| | EZR | Ezrin isoform X1. (584 aa) |
| | CCNE1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa) |
| | LOC101376217 | Induced myeloid leukemia cell differentiation protein Mcl-1 homolog. (197 aa) |
| | STMN1 | Stathmin; Belongs to the stathmin family. (149 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1090 aa) |
| | SERPINB5 | Serpin B5 isoform X1; Belongs to the serpin family. (387 aa) |
| | PDGFB | Platelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (242 aa) |
| | RASSF1 | Ras association domain-containing protein 1 isoform X1. (344 aa) |
| | SPRY2 | Protein sprouty homolog 2. (315 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | EFNA4 | ephrin-A4 isoform X1; Belongs to the ephrin family. (206 aa) |
| | SHC1 | SHC-transforming protein 1 isoform X1. (609 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (492 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (806 aa) |
| | BMI1 | Polycomb complex protein BMI-1 isoform X1. (326 aa) |
| | ZEB2 | Zinc finger E-box-binding homeobox 2 isoform X1. (1217 aa) |
| | HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1136 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (587 aa) |
| | DNMT3B | DNA (Cytosine-5)-methyltransferase 3B isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (877 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (161 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) |
| | PDCD4 | Programmed cell death protein 4 isoform X1. (469 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa) |
| | ST14 | Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (827 aa) |
| | TNXB | tenascin-X. (3794 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1209 aa) |
