Your Input: | |||||
CDH1 | Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa) | ||||
CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) | ||||
BAD | Bcl2-associated agonist of cell death. (168 aa) | ||||
GRB2 | Growth factor receptor-bound protein 2 isoform X1. (217 aa) | ||||
ERBB2 | Receptor protein-tyrosine kinase. (1281 aa) | ||||
MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (161 aa) | ||||
APC2 | Adenomatous polyposis coli protein 2. (2267 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
ARAF | Serine/threonine-protein kinase A-Raf. (606 aa) | ||||
ELK1 | ETS domain-containing protein Elk-1. (435 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) | ||||
CASP9 | Caspase-9 isoform X1; Belongs to the peptidase C14A family. (451 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) | ||||
DDB2 | DNA damage-binding protein 2 isoform X1. (426 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) | ||||
PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (507 aa) | ||||
APC | Adenomatous polyposis coli protein isoform X1. (2844 aa) | ||||
AXIN1 | Axin-1. (867 aa) | ||||
PDPK1 | 3-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa) | ||||
GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) | ||||
HRAS | GTPase HRas isoform X1. (189 aa) | ||||
PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa) | ||||
AXIN2 | Axin-2 isoform X1. (842 aa) | ||||
LOC101376741 | Forkhead box protein O3. (453 aa) | ||||
BAK1 | Bcl-2 homologous antagonist/killer. (211 aa) | ||||
SOS2 | Son of sevenless homolog 2 isoform X1. (1333 aa) | ||||
PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) | ||||
GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) | ||||
SOS1 | Son of sevenless homolog 1 isoform X1. (1333 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa) | ||||
ILK | Integrin-linked protein kinase isoform X1. (452 aa) | ||||
POLK | DNA polymerase kappa. (870 aa) | ||||
MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa) | ||||
GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha isoform X1. (165 aa) | ||||
BAX | Apoptosis regulator BAX isoform X1. (192 aa) | ||||
LOC101367134 | GTPase HRas-like. (177 aa) | ||||
TCF7L1 | Transcription factor 7-like 1. (586 aa) | ||||
PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) | ||||
CTNNB1 | Catenin beta-1 isoform X1. (781 aa) | ||||
RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa) | ||||
CTNNA1 | Catenin alpha-1 isoform X1. (929 aa) | ||||
NRAS | GTPase NRas. (189 aa) | ||||
LOC101375473 | LOW QUALITY PROTEIN: uncharacterized protein LOC101375473. (703 aa) | ||||
CDKN1A | Cyclin-dependent kinase inhibitor 1. (161 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) | ||||
EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1210 aa) | ||||
CTNNA2 | Catenin alpha-2 isoform X1. (953 aa) | ||||
LEF1 | Lymphoid enhancer-binding factor 1 isoform X1. (413 aa) | ||||
MLH1 | DNA mismatch repair protein Mlh1 isoform X1. (759 aa) | ||||
TCF7L2 | Transcription factor 7-like 2 isoform X1. (621 aa) | ||||
BRAF | Serine/threonine-protein kinase B-raf. (772 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1209 aa) |