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| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | BCL2L1 | Bcl-2-like protein 1 isoform X1. (233 aa) |
| | E2F1 | Transcription factor E2F1. (431 aa) |
| | HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | LOC101363382 | Glutathione S-transferase P. (229 aa) |
| | LOC101363675 | Glutathione S-transferase P-like; Belongs to the GST superfamily. (228 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | FZD1 | Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (648 aa) |
| | ACTB | Actin, cytoplasmic 1 isoform X2. (375 aa) |
| | BAD | Bcl2-associated agonist of cell death. (168 aa) |
| | GRB2 | Growth factor receptor-bound protein 2 isoform X1. (217 aa) |
| | E2F2 | Transcription factor E2F2. (442 aa) |
| | ARID1A | AT-rich interactive domain-containing protein 1A isoform X1. (2282 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (161 aa) |
| | SHC2 | SHC-transforming protein 2. (586 aa) |
| | APC2 | Adenomatous polyposis coli protein 2. (2267 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | TXNRD3 | Thioredoxin reductase 3 isoform X1. (629 aa) |
| | ARID2 | AT-rich interactive domain-containing protein 2. (1836 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | DPF1 | Zinc finger protein neuro-d4 isoform X1. (424 aa) |
| | TGFB1 | Transforming growth factor beta-1. (287 aa) |
| | SHC4 | SHC-transforming protein 4. (630 aa) |
| | ARAF | Serine/threonine-protein kinase A-Raf. (606 aa) |
| | ELK1 | ETS domain-containing protein Elk-1. (435 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | ACTL6A | Actin-like protein 6A isoform X1; Belongs to the actin family. (434 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | DVL2 | Segment polarity protein dishevelled homolog DVL-2 isoform X1. (734 aa) |
| | TGFA | Protransforming growth factor alpha isoform X1. (160 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | KEAP1 | Kelch-like ECH-associated protein 1. (624 aa) |
| | ACTL6B | Actin-like protein 6B; Belongs to the actin family. (426 aa) |
| | FZD9 | Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (597 aa) |
| | TGFB3 | Transforming growth factor beta-3. (461 aa) |
| | SMARCC1 | SWI/SNF complex subunit SMARCC1. (1050 aa) |
| | RB1 | Retinoblastoma-associated protein. (936 aa) |
| | DDB2 | DNA damage-binding protein 2 isoform X1. (426 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | LOC101377598 | Glutathione S-transferase theta-4; Belongs to the GST superfamily. (241 aa) |
| | LOC101377874 | Glutathione S-transferase theta-1 isoform X1; Belongs to the GST superfamily. (240 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | LOC101377307 | Glutathione S-transferase theta-1-like; Belongs to the GST superfamily. (242 aa) |
| | SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa) |
| | LOC101378163 | Glutathione S-transferase theta-1-like isoform X1; Belongs to the GST superfamily. (240 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (507 aa) |
| | SMARCD1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D. (515 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa) |
| | APC | Adenomatous polyposis coli protein isoform X1. (2844 aa) |
| | SMARCC2 | SWI/SNF complex subunit SMARCC2 isoform X1. (1244 aa) |
| | CDK4 | Cyclin-dependent kinase 4 isoform X1; Belongs to the protein kinase superfamily. (340 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | FZD6 | Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa) |
| | AXIN1 | Axin-1. (867 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) |
| | NFE2L2 | Nuclear factor erythroid 2-related factor 2 isoform X1. (605 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | IGF2 | LOW QUALITY PROTEIN: insulin-like growth factor II. (198 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa) |
| | FZD5 | Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (590 aa) |
| | AXIN2 | Axin-2 isoform X1. (842 aa) |
| | SMARCD2 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2. (531 aa) |
| | MGST2 | Microsomal glutathione S-transferase 2. (146 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | DVL3 | Segment polarity protein dishevelled homolog DVL-3 isoform X1. (716 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | MGST1 | Microsomal glutathione S-transferase 1. (155 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa) |
| | GAB1 | GRB2-associated-binding protein 1 isoform X1. (724 aa) |
| | GSTM3 | Glutathione S-transferase. (226 aa) |
| | FZD2 | Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa) |
| | DVL1 | Segment polarity protein dishevelled homolog DVL-1 isoform X1. (693 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer. (211 aa) |
| | SOS2 | Son of sevenless homolog 2 isoform X1. (1333 aa) |
| | MGST3 | Microsomal glutathione S-transferase 3. (152 aa) |
| | WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) |
| | MET | Hepatocyte growth factor receptor. (1382 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | LOC101386898 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D. (483 aa) |
| | LOC101367574 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3-like. (309 aa) |
| | FRAT1 | Proto-oncogene FRAT1. (280 aa) |
| | FRAT2 | GSK-3-binding protein FRAT2. (233 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) |
| | SHC3 | SHC-transforming protein 3. (587 aa) |
| | SOS1 | Son of sevenless homolog 1 isoform X1. (1333 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | GSTA4 | Glutathione S-transferase A4; Belongs to the GST superfamily. (222 aa) |
| | LOC101375310 | Glutathione S-transferase A2; Belongs to the GST superfamily. (223 aa) |
| | LOC101379552 | Glutathione S-transferase. (251 aa) |
| | LOC101379260 | Glutathione S-transferase A1-like; Belongs to the GST superfamily. (232 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2559 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | PBRM1 | Protein polybromo-1 isoform X1. (1725 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1117 aa) |
| | FZD3 | Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | POLK | DNA polymerase kappa. (870 aa) |
| | PHF10 | PHD finger protein 10 isoform X1. (451 aa) |
| | E2F3 | Transcription factor E2F3 isoform X1. (468 aa) |
| | FZD4 | Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | SMARCA2 | Probable global transcription activator SNF2L2. (1525 aa) |
| | TXNRD2 | Thioredoxin reductase 2, mitochondrial. (525 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha isoform X1. (165 aa) |
| | BAX | Apoptosis regulator BAX isoform X1. (192 aa) |
| | LOC101367134 | GTPase HRas-like. (177 aa) |
| | TCF7L1 | Transcription factor 7-like 1. (586 aa) |
| | FZD10 | Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) |
| | HMOX1 | Heme oxygenase 1. (322 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa) |
| | FZD8 | Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (689 aa) |
| | GSTO2 | Glutathione S-transferase omega-2 isoform X1; Belongs to the GST superfamily. (243 aa) |
| | CTNNB1 | Catenin beta-1 isoform X1. (781 aa) |
| | LOC101376063 | LOW QUALITY PROTEIN: glutathione S-transferase Mu 1; Belongs to the GST superfamily. (220 aa) |
| | GSTO1 | Glutathione S-transferase omega-1 isoform X1; Belongs to the GST superfamily. (241 aa) |
| | SMARCE1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1. (399 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa) |
| | LOC101379696 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1. (294 aa) |
| | SMARCA4 | Transcription activator BRG1 isoform X1. (1683 aa) |
| | DPF3 | Zinc finger protein DPF3. (378 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | ARID1B | AT-rich interactive domain-containing protein 1B. (2106 aa) |
| | CSNK1A1 | Casein kinase I isoform alpha isoform X1; Belongs to the protein kinase superfamily. (365 aa) |
| | SHC1 | SHC-transforming protein 1 isoform X1. (609 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1304 aa) |
| | BRD7 | Bromodomain-containing protein 7 isoform X1. (652 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (161 aa) |
| | NQO1 | NAD(P)H dehydrogenase [quinone] 1. (273 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) |
| | FZD7 | Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) |
| | LEF1 | Lymphoid enhancer-binding factor 1 isoform X1. (413 aa) |
| | TCF7L2 | Transcription factor 7-like 2 isoform X1. (621 aa) |
| | BRAF | Serine/threonine-protein kinase B-raf. (772 aa) |
| | TXNRD1 | Thioredoxin reductase 1, cytoplasmic; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (930 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein 5. (1451 aa) |
| | LOC101365279 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1. (426 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1209 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa) |
